Nanotechnology

Publication Title: 
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy

Biologically inspired experimental process in synthesising nanoparticles is of great interest in present scenario. Biosynthesis of nanoparticles is considered to be one of the best green techniques in synthesising metal nanoparticles. Here, an in situ green biogenic synthesis of gold nanoparticles using aqueous extracts of Terminalia chebula as reducing and stabilizing agent is reported. Gold nanoparticles were confirmed by surface plasmon resonance in the range of 535 nm using UV-visible spectrometry.

Author(s): 
Kumar, Kesarla Mohan
Mandal, Badal Kumar
Sinha, Madhulika
Krishnakumar, Varadhan
Publication Title: 
International Journal of Cancer. Journal International Du Cancer

Ovarian cancer ranks fifth in cancer fatalities among American women. Although curable at early stages with surgery, most women are diagnosed with symptoms of late-stage metastatic disease. Moreover, none of the current diagnostic techniques are clinically recommended for at-risk women as they preferentially target low-grade tumors (which do not affect longevity) and fail to capture early signatures of more lethal serous tumors which originate in the fimbrae region of the fallopian tubes. Hence, the early detection of ovarian cancer is challenging given the current strategy.

Author(s): 
Damania, Dhwanil
Roy, Hemant K.
Kunte, Dhananja
Hurteau, Jean A.
Subramanian, Hariharan
Cherkezyan, Lusik
Krosnjar, Nela
Shah, Maitri
Backman, Vadim
Publication Title: 
The Keio Journal of Medicine

Rapid progress is being made in our ability to modify the aging process. Rather than serving as a period of debility and decreasing health, for many people, the later years of life are becoming a period of continued productivity, independence and good health. Progress is also being made in increasing average lifespan. The leading causes of death (cardiovascular disease, cancer, lung disease, diabetes) are the end result of decades-long processes. With current knowledge, it is possible to delay the onset of these diseases.

Author(s): 
Grossman, Terry
Publication Title: 
Therapeutic Delivery

The Institute of Holistic Medical Sciences (IHMS, Kottayam, Kerala, India); the Institute of Macromolecular Science and Engineering (IMSE, Kottayam, Kerala, India) and Mathew Ayurveda und Venen Klinik (MUVK, Klegenfurt, Austria) have jointly conducted a 3-day world conference on Nanomedicine and Drug Delivery (WCN 2011) in Kottayam, Kerala, India from 11-13 March 2011. Application of nanotechnology for treatment, diagnosis, monitoring and control of biological systems has been referred to as 'nanomedicine' by the NIH.

Author(s): 
Ninan, Neethu
Thomas, Sabu
George, Anne
Sebastian, Mathew
Publication Title: 
Journal of Biochemistry and Molecular Biology

The study of whole patterns of changes in protein expression and their modifications, or proteomics, presents both technological advances as well as formidable challenges to biological researchers. Nutrition research and the food sciences in general will be strongly influenced by the new knowledge generated by the proteomics approach. This review examines the different aspects of proteomics technologies, while emphasizing the value of consideration of "traditional" aspects of protein separation.

Author(s): 
Barnes, Stephen
Kim, Helen
Publication Title: 
FASEB journal: official publication of the Federation of American Societies for Experimental Biology

The aim of this research was to validate transcription magnetic resonance (MR) imaging (MRI) for gene transcript targeting in acute neurological disorders in live subjects. We delivered three MR probe variants with superparamagnetic iron oxide nanoparticles (SPION, a T2 susceptibility agent) linked to a phosphorothioate-modified oligodeoxynucleotide (sODN) complementary to c-fos mRNA (SPION-cfos) or beta-actin mRNA (SPION-beta-actin) and to sODN with random sequence (SPION-Ran).

Author(s): 
Liu, Christina H.
Huang, Shuning
Cui, Jiankun
Kim, Young R.
Farrar, Christian T.
Moskowitz, Michael A.
Rosen, Bruce R.
Liu, Philip K.
Publication Title: 
Zhong Xi Yi Jie He Xue Bao = Journal of Chinese Integrative Medicine

The ancient theory and technology which are related to preventive treatment of disease by dietetic regulation and coordinating meridian according to 25 tones have been developed in the early 21st century. It is proved in sonocytology by nanotechnology that cells are able to produce noise, and the noise will change at first when the cells have any disorders. This theory is in accordance with the one in Huangdi Neijing. The nanotechnology can be introduced into the basic research of traditional Chinese medicine and may contribute to the modernization of traditional Chinese medicine.

Author(s): 
Gao, Ye-Tao
Shi, Shan-Quan
Pan, Hui-Wei
Publication Title: 
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae

Nanobiological technology is an important research field in nanotechnology and has extensive applications in medicine. Although initiated lately, application of nanobiological technology in medicine is advancing in good pace in China, mainly involves in fields including nano-scale pharmaceutical carrier, nanoscale diagnostic technology, nanobiomaterials, and nano-scale traditional Chinese medicine.

Author(s): 
Zhang, Yang-de
Publication Title: 
Zhong Xi Yi Jie He Xue Bao = Journal of Chinese Integrative Medicine

The past decade has witnessed the remarkable progress on nanotechnology and nanoherb. With the globally rapid development of nanotechnology, we are considering to construct new nanoformula systems of traditional Chinese medicine (TCM) by using porous materials, multilayered core-shell particles or nanoparticles containing various multifunctional parts.

Author(s): 
Ling, Chang-quan
Su, Yong-hua
Publication Title: 
International Journal of Nanomedicine

BACKGROUND: San-Huang-Xie-Xin-Tang (SHXXT) decoction, a traditional Chinese medicine containing Rhei rhizome, Coptidis rhizome, and Scutellariae radix, is widely used in hepatoprotective therapy. However, preparation of the decoction requires addition of boiling water that causes loss of numerous effective components. METHODS: To improve the bioavailability of the decoction, nanoscale SHXXT was developed. Chloroform-induced liver injury and hepatic stellate cell activity in mice were used to demonstrate the hepatoprotective characteristics of nanoscale SHXXT decoction.

Author(s): 
Huang, Sherry
Chang, Shu-Jen
Yang, Miffy
Chen, Justin Jin-Ching
Chang, Walter H.
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