Zhong Xi Yi Jie He Xue Bao = Journal of Chinese Integrative Medicine
OBJECTIVE: To study the mechanism of Shenkangling (SKL), a compound traditional Chinese herbal medicine, combined with prednisone in treating adriamycin-induced nephropathy in rats. METHODS: Sixty-six SD male rats were randomly divided into normal control group, untreated group, prednisone group, SKL group and SKL plus prednisone group. Except the normal control group, rats were injected once via caudal vein with adriamycin (5.5 mg/kg) to induce nephropathy. Then, the rats were administered with prednisone, SKL, prednisone plus SKL or distilled water for 3 weeks, respectively.