Neurocognitive Disorders

Publication Title: 
The American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association

A scoping review was conducted to describe how mindfulness is used in physical rehabilitation, identify implications for occupational therapy practice, and guide future research on clinical mindfulness interventions. A systematic search of four literature databases produced 1,524 original abstracts, of which 16 articles were included.

Author(s): 
Hardison, Mark E.
Roll, Shawn C.
Publication Title: 
Behavioural Brain Research

The epigenetic marking of chromatin provides a ubiquitous means for cells to shape and maintain their identity, and to react to environmental stimuli via specific remodeling. Such an epigenetic code of the core components of chromatin, DNA and histone proteins, can thus be stable but is also highly dynamic. In the nervous system, epigenetic codes are critical for basic cellular processes such as synaptic plasticity, and for complex behaviours such as learning and memory.

Author(s): 
Gr‰ff, Johannes
Mansuy, Isabelle M.
Publication Title: 
The American Journal of Clinical Nutrition

BACKGROUND: Fetal alcohol spectrum disorders (FASDs) are conditions characterized by physical anomalies, neurodevelopmental abnormalities, and neurocognitive deficits, including intellectual, executive, and memory deficits. There are no specific biological treatments for FASDs, but rodent models have shown that prenatal or postnatal choline supplementation reduces cognitive and behavioral deficits. Potential mechanisms include phospholipid production for axonal growth and myelination, acetylcholine enhancement, and epigenetic effects.

Author(s): 
Wozniak, Jeffrey R.
Fuglestad, Anita J.
Eckerle, Judith K.
Fink, Birgit A.
Hoecker, Heather L.
Boys, Christopher J.
Radke, Joshua P.
Kroupina, Maria G.
Miller, Neely C.
Brearley, Ann M.
Zeisel, Steven H.
Georgieff, Michael K.
Publication Title: 
The American Journal of Psychiatry

De Clerembault identified a syndrome associated with delusional loving, and it has since been described in association with various diagnoses including paranoia, schizophrenia, affective disorder, and mental retardation. The authors document its coexistence with bipolar disorder and its response to lithium.

Author(s): 
Remington, G.
Book, H.
Publication Title: 
The British Journal of Psychiatry: The Journal of Mental Science

A case of de ClÈrambault syndrome, secondary to paranoid schizophrenia, in a Saudi woman is documented. Cultural factors were found ineffective in modifying or preventing symptoms. Erotomania appeared to arise from the same dynamics as those of the Western patients and to follow the same pattern.

Author(s): 
el-Assra, A.
Publication Title: 
The American Journal of Psychiatry

Twenty-eight patients with erotomanic delusions were compared with 80 patients with other delusions to clarify questions about diagnosis and course of illness in erotomania. The erotomanic patients were a heterogeneous group with respect to both diagnosis and course. They had significantly more manic symptoms than the comparison group and more affective diagnoses than would be expected from the literature; 25% (N = 7) had schizoaffective disorder and 7% (N = 2) had bipolar disorder.

Author(s): 
Rudden, M.
Sweeney, J.
Frances, A.
Publication Title: 
Psychopathology

The concept of erotomania is discussed and the literature surveyed. The aim of the study is to present a long-term personal follow-up evaluation of cases with erotomania-like symptoms. In a material of 1,802 consecutively admitted patients, 6 (0.3%) presented symptoms suggestive of erotomania. They have been personally followed up 2 or 3 times by the authors over a period of 22-35 years. Our sample was characterized by avoidant and/or paranoid premorbid personality traits with difficulties in establishing relationships, and life-long social isolation.

Author(s): 
Retterst¯l, N.
Opjordsmoen, S.
Publication Title: 
The Journal of Clinical Psychiatry

De ClÈrambault's syndrome is said to usually occur in heterosexual women with little overt sexual experience. The authors present five cases of women with considerable sexual experience including, in some instances, homosexual activity and discuss their diagnosis of De ClÈrambault's syndrome in the context of what has been reported in the literature.

Author(s): 
Giannini, A. J.
Slaby, A. E.
Robb, T. O.
Publication Title: 
The British Journal of Psychiatry: The Journal of Mental Science

A case of secondary erotomania co-existent with Capgras' syndrome presented with features that have not been reported before. The case is suggested to be a variant of de ClÈrambault's syndrome. The role of cultural factors in altering the clinical picture is insignificant.

Author(s): 
Zarrouk, E. T.
Publication Title: 
The British Journal of Medical Psychology

In this study of erotic transference the phenomenon is defined in the manner of Freud (1915) and Blum (1973). It involves a circumscribed behaviour which consists of an erotic preoccupation with the therapist which often has the quality of an obsession. It is prolonged, usually for months or years, is relatively immutable, and can be seen as a milder variant of de Clerembault's syndrome. It is suggested that the psychic purpose of the preoccupation is to maintain a threatened sense of self.

Author(s): 
Kotze, B.
Meares, R.

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