Neurologic Examination

Publication Title: 
AACN clinical issues

Patients with severe traumatic brain injury resulting in increased intracranial pressure refractory to first-tier interventions challenge the critical care team. After exhausting these initial interventions, critical care practitioners may utilize barbiturate-induced coma in an attempt to reduce the intracranial pressure. Titrating appropriate levels of barbiturate is imperative. Underdosing the drug may fail to control the intracranial pressure, whereas overdosing may lead to untoward effects such as hypotension and cardiac compromise.

Author(s): 
Bader, Mary Kay
Arbour, Richard
Palmer, Sylvain
Publication Title: 
The Journal of the American Board of Family Practice

BACKGROUND: Sexual problems are common but infrequently diagnosed. They are classified into four major categories: (1) sexual desire disorders, (2) sexual arousal disorders, (3) orgasmic disorders, and (4) sexual pain disorders. METHODS: MEDLINE files from 1966 to the present were searched using the specific sexual dysfunctions as key words along with the general key word "sexual dysfunction" to review the published literature. Additional articles came from the reference lists of dysfunction-specific reviews.

Author(s): 
Halvorsen, J. G.
Metz, M. E.
Publication Title: 
La Presse Médicale
Author(s): 
Aboulker, P.
Chertok, L.
Publication Title: 
The Journal of the American Board of Family Practice / American Board of Family Practice

BACKGROUND: Sexual problems are common but infrequently diagnosed. They are classified into four major categories: (1) sexual desire disorders, (2) sexual arousal disorders, (3) orgasmic disorders, and (4) sexual pain disorders. METHODS: MEDLINE files from 1966 to the present were searched using the specific sexual dysfunctions as key words along with the general key word "sexual dysfunction" to review the published literature. Additional articles came from the reference lists of dysfunction-specific reviews.

Author(s): 
Halvorsen, J. G.
Metz, M. E.
Publication Title: 
AACN clinical issues

Patients with severe traumatic brain injury resulting in increased intracranial pressure refractory to first-tier interventions challenge the critical care team. After exhausting these initial interventions, critical care practitioners may utilize barbiturate-induced coma in an attempt to reduce the intracranial pressure. Titrating appropriate levels of barbiturate is imperative. Underdosing the drug may fail to control the intracranial pressure, whereas overdosing may lead to untoward effects such as hypotension and cardiac compromise.

Author(s): 
Bader, Mary Kay
Arbour, Richard
Palmer, Sylvain
Publication Title: 
L'Encéphale

Conversion disorder refers to the occurrence of neurological-like symptoms or deficits that are neither intentionally produced nor simulated. While it cannot be explained by an organic disease, it is often related to psychological events. CASE REPORT: We report the case of a 33-year-old patient with a fluctuating hysterical tetraplegia, which had started three years earlier. After the failure or the exhaustion of several biological (psychotropic medication, transcranial magnetic stimulation) and psychotherapeutic strategies, treatment with electroconvulsive therapy (ECT) was conducted.

Author(s): 
Gaillard, A.
Gaillard, R.
Mouaffak, F.
Radtchenko, A.
Lôo, H.
Publication Title: 
The American Journal of Tropical Medicine and Hygiene

The qinghaosu (artemisinin) group of drugs is the most important new class of antimalarials developed in the last fifty years. Although there has been no clinical evidence of neurotoxicity, an unusual pattern of damage to specific brain-stem nuclei has been reported in experimental animals receiving high doses of arteether or artemether.

Author(s): 
Kissinger, E.
Hien, T. T.
Hung, N. T.
Nam, N. D.
Tuyen, N. L.
Dinh, B. V.
Mann, C.
Phu, N. H.
Loc, P. P.
Simpson, J. A.
White, N. J.
Farrar, J. J.
Publication Title: 
Malaria Journal

BACKGROUND: Mefloquine and artesunate combination therapy is the recommended first-line treatment for uncomplicated malaria throughout much of south-east Asia. Concerns have been raised about the potential central nervous system (CNS) effects of both drug components and there are no detailed reports in very young children. METHODS: Children, aged between three months and five years, with acute uncomplicated Plasmodium falciparum malaria were randomized to either 7 days of artesunate monotherapy or the same schedule of artesunate plus mefloquine on day 7 and 8.

Author(s): 
Ambler, Michael T.
Dubowitz, Lilly M.
Arunjerdja, Ratree
Hla, Eh Paw
Thwai, Kyaw Lay
Viladpainguen, Jacher
Singhasivanon, Pratap
Luxemburger, Christine
Nosten, François
McGready, Rose
Publication Title: 
Neurology

BACKGROUND: Vitamin D deficiency has potential adverse effects on neurocognitive health and subcortical function. However, no studies have examined the association between vitamin D status, dementia, and cranial MRI indicators of cerebrovascular disease (CVD). METHODS: Cross-sectional investigation of 25-hydroxyvitamin D [25(OH)D], dementia, and MRI measures of CVD in elders receiving home care (aged 65-99 years) from 2003 to 2007. RESULTS: Among 318 participants, the mean age was 73.5 +/- 8.1 years, 231 (72.6%) were women, and 109 (34.3%) were black.

Author(s): 
Buell, J. S.
Dawson-Hughes, B.
Scott, T. M.
Weiner, D. E.
Dallal, G. E.
Qui, W. Q.
Bergethon, P.
Rosenberg, I. H.
Folstein, M. F.
Patz, S.
Bhadelia, R. A.
Tucker, K. L.
Publication Title: 
Behavioural Brain Research

In this study we transplanted bone marrow mononuclear cells (BM-MNCs) or microglia into rats that had undergone permanent cerebral ischemia and observed the distribution or morphology of transplanted cells in vivo. In addition, we compared the effects of BM-MNCs and microglia on infarct volume, brain water content, and functional outcome after permanent cerebral ischemia. BM-MNCs and microglia were obtained from femur and brain, respectively, of newborn rats.

Author(s): 
Jiang, Chao
Wang, Jianping
Yu, Lie
Ou, Chunying
Liu, Xi
Zhao, Xiaochun
Wang, Jian

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