Nociceptive Pain

Publication Title: 
Current Opinion in Supportive and Palliative Care

PURPOSE OF REVIEW: Pain is a significant concern in people with chronic wounds. A systematized approach is recommended for the management of wound-associated pain with the objectives to address pain relief, increase function, and restore overall quality of life. RECENT FINDINGS: Combinations of pharmacological agents are often recommended based on varying degree of pain severity, coexisting nociceptive and neuropathic pain, and chronic inflammation related to wound-associated pain.

Author(s): 
Woo, Kevin Y.
Abbott, Laura K.
Librach, Lawrence
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: Chronic pain is frequent in persons living with spinal cord injury (SCI). Conventionally, the pain is treated pharmacologically, yet long-term pain medication is often refractory and associated with side effects. Non-pharmacological interventions are frequently advocated, although the benefit and harm profiles of these treatments are not well established, in part because of methodological weaknesses of available studies.

Author(s): 
Boldt, Inga
Eriks-Hoogland, Inge
Brinkhof, Martin W. G.
de Bie, Rob
Joggi, Daniel
von Elm, Erik
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: Chronic pain is frequent in persons living with spinal cord injury (SCI). Conventionally, the pain is treated pharmacologically, yet long-term pain medication is often refractory and associated with side effects. Non-pharmacological interventions are frequently advocated, although the benefit and harm profiles of these treatments are not well established, in part because of methodological weaknesses of available studies.

Author(s): 
Boldt, Inga
Eriks-Hoogland, Inge
Brinkhof, Martin W. G.
de Bie, Rob
Joggi, Daniel
von Elm, Erik
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: Chronic pain is frequent in persons living with spinal cord injury (SCI). Conventionally, the pain is treated pharmacologically, yet long-term pain medication is often refractory and associated with side effects. Non-pharmacological interventions are frequently advocated, although the benefit and harm profiles of these treatments are not well established, in part because of methodological weaknesses of available studies.

Author(s): 
Boldt, Inga
Eriks-Hoogland, Inge
Brinkhof, Martin W. G.
de Bie, Rob
Joggi, Daniel
von Elm, Erik
Publication Title: 
Pain

Recent functional brain connectivity studies have contributed to our understanding of the neurocircuitry supporting pain perception. However, evoked-pain connectivity studies have employed cutaneous and/or brief stimuli, which induce sensations that differ appreciably from the clinical pain experience. Sustained myofascial pain evoked by pressure cuff affords an excellent opportunity to evaluate functional connectivity change to more clinically relevant sustained deep-tissue pain.

Author(s): 
Kim, Jieun
Loggia, Marco L.
Edwards, Robert R.
Wasan, Ajay D.
Gollub, Randy L.
Napadow, Vitaly
Publication Title: 
African journal of traditional, complementary, and alternative medicines: AJTCAM / African Networks on Ethnomedicines

Aconiti Brachypodi Radix, belonging to the genus of Aconitum (Family Ranunculaceae), are used clinically as anti-rheumatic, anti-inflammatory and anti-nociceptive in traditional medicine of China. However, its mechanism and influence on nociceptive threshold are unknown and need further investigation. The analgesic effects of ethanolic extract of Aconiti Brachypodi Radix (EABR) were thus studied in vivo and in vitro. Three pain models in mice were used to assess the effect of EABR on nociceptive threshold.

Author(s): 
Ren, Wei
Yuan, Lin
Li, Jun
Huang, Xian-Ju
Chen, Su
Zou, Da-Jiang
Liu, Xiangming
Yang, Xin-Zhou
Publication Title: 
Journal of Oral & Facial Pain and Headache

AIMS: To clarify the antiallodynic effects of the α2-adrenergic receptor antagonist mirtazapine compared with those of gabapentin and pregabalin in a rat model of orofacial neuropathic pain. METHODS: Mirtazapine (10, 30, and 100 μg), gabapentin (10, 30, and 100 μg), and pregabalin (3, 10, and 30 μg) were administered intrathecally to eight male Sprague-Dawley rats with orofacial neuropathic pain induced by chronic constriction injury of the infraorbital nerve that had been carried out 2 weeks previously.

Author(s): 
Nakai, Kunihiro
Nakae, Aya
Hashimoto, Ryota
Mashimo, Takashi
Hosokawa, Ko
Publication Title: 
Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række

BACKGROUND: Chronic pain following spinal cord injury is common, and may result in a substantially reduced quality of life. The aim of the paper is to provide an overview of pain conditions resulting from spinal cord injuries and an update on therapy options. METHOD: The article is based on literature searches in PubMed review articles for the period 2006-2011, using the search phrases «pain and spinal cord injury/injuries», «chronic pain and spinal cord injury/injuries» and «neuropathic pain and spinal cord injury/injuries».

Author(s): 
Rekand, Tiina
Hagen, Ellen Merete
Grønning, Marit
Publication Title: 
Life Sciences

AIMS: The purpose of this study was to examine whether the use of intraperitoneal or intrathecal amitriptyline combined with electroacupuncture modifies the tail-flick reflex and incision pain in rats that normally do not have analgesia to electroacupuncture in the tail-flick test (non-responder rats).

Author(s): 
Fais, Rafael S.
Reis, G. M.
Rossaneis, A. C.
Silveira, J. W. S.
Dias, Q. M.
Prado, W. A.
Publication Title: 
European Journal of Physical and Rehabilitation Medicine

One of the objectives of the Professional Practice Committee (PPC) of the Physical and Rehabilitation Medicine (PRM) Section of the Union of European Medical Specialists (UEMS) is the development of the field of competence of PRM physicians in Europe. To achieve this objective, UEMS PRM Section PPC has adopted a systematic action plan of preparing a series of papers describing the role of PRM physicians in a number of disabling health conditions, based on the evidence of effectiveness of PRM interventions.

Author(s): 
Oral, A.
Ilieva, E. M.
Küçükdeveci, A. A.
Varela, E.
Valero, R.
Berteanu, M.
Christodoulou, N.
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