Obesity, Morbid

Publication Title: 
American Journal of Surgery

Obesity is increasing in epidemic proportions world-wide. Even mild degrees of obesity have adverse health effects and are associated with diminished longevity. For this reason aggressive dietary intervention is recommended. Patients with body mass indices exceeding 40 have medically significant obesity in which the risk of serious health consequences is substantial, with concomitant significant reductions in life expectancy. For these patients, sustained weight loss rarely occurs with dietary intervention. For the appropriately selected patients, surgery is beneficial.

Livingston, Edward H.
Publication Title: 
Obesity Reviews: An Official Journal of the International Association for the Study of Obesity

Short-term studies indicate that intentional weight loss (IWL) among obese persons significantly improves health variables that are often precursors or markers of chronic diseases (e.g. heart diseases, type-2 diabetes). Hence, it is logical to assume that IWL among obese persons would lead to increased longevity.

Yang, D.
Fontaine, K. R.
Wang, C.
Allison, D. B.
Publication Title: 
The American Journal of Psychiatry
McDanal, C. E.
Publication Title: 
Acta Anaesthesiologica Scandinavica

Closed-loop control of propofol delivery was instituted in three patients who received a propofol infusion as part of: (Case 1) general "balanced" anesthesia, (Case 2) total intravenous anesthesia, and (Case 3) monitored anesthesia care. The bispectral index was the input variable used in a proportioned, integral and differential controller to determine the infusion rate of propofol required to maintain a stable level of hypnosis (Cases 1 and 2) or sedation (Case 3).

Sakai, T.
Matsuki, A.
White, P. F.
Giesecke, A. H.
Publication Title: 
Acta Anaesthesiologica Scandinavica

BACKGROUND: The objective of anaesthesia is to provide hypnosis, analgesia and adequate conditions during surgery. It is difficult to establish the appropriate dose of general anaesthetic drugs in the morbidly obese patient. Moreover, there are conflicting data concerning adequate anaesthesia levels and the severity of postoperative pain. The aim of this study was to investigate the relationship between the spectral edge frequency (SEF) during general anaesthesia and the severity of immediate postoperative pain following gastric banding surgery in morbidly obese patients.

Gurman, G. M.
Popescu, M.
Weksler, N.
Steiner, O.
Avinoah, E.
Porath, A.
Publication Title: 
British Journal of Anaesthesia

BACKGROUND: The aim of this study was to compare desflurane vs sevoflurane kinetics and dynamics in morbidly obese patients and their recovery profile when no premedication had been used. METHODS: Twenty-eight unpremedicated obese patients were randomly allocated to receive either sevoflurane (n = 14) or desflurane (n = 14) as the main anaesthetic agent. After induction of anaesthesia, either sevoflurane 2% or desflurane 6% was administered for 30 min via a non-rebreathing circuit.

La Colla, L.
Albertin, A.
La Colla, G.
Mangano, A.
Publication Title: 
Anaesthesia and Intensive Care

A 73-year-old morbidly obese female patient (weight 125 kg, height 156 cm) was scheduled for cataract surgery of her right eye. Due to a number of severe co-morbidities general anaesthesia was contraindicated. However the patient was very anxious and requested sedation if the procedure was to be undertaken under local anaesthesia. She responded very positively to the proposal of utilising perioperative hypnosis. Hypnotic induction was achieved with the heavy eyelid technique, putting the patient into trance within 30 seconds.

Kiss, G.
Butler, J.
Publication Title: 
Anesthesia and Analgesia

BACKGROUND: Most pharmacokinetic (PK) models used for propofol administration are based on studies in normal-weight patients. Extrapolation of these models for morbidly obese patients is controversial. Using 2 PK models and a target-controlled infusion system, we determined the predicted propofol effect-site concentration (Ce) needed for induction of anesthesia in morbidly obese subjects using total body weight.

Echevarría, Ghislaine C.
Elgueta, María F.
Donoso, María T.
Bugedo, Diego A.
Cortínez, Luis I.
Muñoz, Hernán R.
Publication Title: 

BACKGROUND: Patient cooperation is crucial for the success of noninvasive positive pressure ventilation (NPPV). This study evaluated the efficacy of medical hypnosis to reduce anticipatory anxiety and acclimatization time in children who are candidates for long-term NPPV. METHODS: Medical hypnosis was performed by a trained nurse. The acclimatization time and long-term compliance with NPPV were evaluated. RESULTS: Hypnosis was performed in nine children aged 2 to 15 years.

Delord, Vincent
Khirani, Sonia
Ramirez, Adriana
Joseph, Erick Louis
Gambier, Clotilde
Belson, Maryse
Gajan, Francis
Fauroux, Brigitte
Publication Title: 
Obesity Surgery

BACKGROUND: Parenteral administration of opioids and NSAIDs has been the mainstay for postoperative pain control in patients undergoing laparoscopic adjustable gastric banding (LAGB). Both classes of drugs, however, are associated with serious adverse effects. An addition of complimentary analgesic techniques may decrease requirement for traditional analgesics, thus reducing the incidence of side-effects. We designed the study to evaluate the effectiveness of Lavender aromatherapy in reducing opioid requirements after LAGB.

Kim, Jung T.
Ren, Christine J.
Fielding, George A.
Pitti, Abhishek
Kasumi, Takeo
Wajda, Michael
Lebovits, Allen
Bekker, Alex


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