Orchiectomy

Publication Title: 
Maturitas

CONTEXT AND OBJECTIVE: The aim of this study was to describe hot flushes in men with prostate cancer, and their treatment methods. METHOD: A systematic review was conducted of the literature indexed between 1966 and 2009 on the MEDLINE, the ISI Web of Knowledge, Cinahl and PsycINFO. Of 252 articles identified, 32 were selected for consideration of their complete texts, of which five were subject to detailed analysis.

Author(s): 
Frisk, Jessica
Publication Title: 
Maturitas

CONTEXT AND OBJECTIVE: The aim of this study was to describe hot flushes in men with prostate cancer, and their treatment methods. METHOD: A systematic review was conducted of the literature indexed between 1966 and 2009 on the MEDLINE, the ISI Web of Knowledge, Cinahl and PsycINFO. Of 252 articles identified, 32 were selected for consideration of their complete texts, of which five were subject to detailed analysis.

Author(s): 
Frisk, Jessica
Publication Title: 
Journal of Sex & Marital Therapy

A case report of young male patient with erotomania following seminoma and orchiectomy is described in this article. The probable dynamics that lead to this delusion are then discussed. This case report demonstrates the cooperation between the oncology ward and the psychiatric liaison service.

Author(s): 
Mazeh, D.
Merimsky, O.
Melamed, Y.
Inbar, M.
Publication Title: 
Journal of Pharmacobio-Dynamics

Following in vivo treatment with carrageenan, sex-related differences in alteration of hepatic drug metabolism were found in the rat. In adult male rats, marked decreases were observed in hepatic 9000 x g supernatant cytochrome P-450 content and in the biotransformation of hexobarbital, aminopyrine, ethylmorphine, and meperidine. Hexobarbital hypnosis was significantly prolonged by carrageenan treatment in intact and testectomized animals as compared to their respective controls.

Author(s): 
Ishikawa, M.
Sasaki, K.
Ozaki, M.
Takayanagi, Y.
Sasaki, K.
Publication Title: 
Physiology & Behavior

Adult voles show sexual differences in their behavioral responses to estrogen. To determine whether this sexual dimorphism is related to early androgen exposure as it is in other rodents, female voles were treated neonatally with testosterone. In addition, males were castrated neonatally or treated perinatally with either the antiandrogen, flutamide or with the antiaromatase, ATD. When androgenized females were treated with estrogen in adulthood, they exhibited normal sexual behaviors.

Author(s): 
Petersen, S. L.
Publication Title: 
Cancer Research

Androgen-dependent human LNCaP 104-S tumor xenografts progressed to androgen-independent relapsed tumors (104-Rrel) in athymic mice after castration. The growth of 104-Rrel tumors was suppressed by testosterone. However, 104-Rrel tumors adapted to androgen and regrew as androgen-stimulated 104-Radp tumors. Androgen receptor expression in tumors and serum prostate-specific antigen increased during progression from 104-S to 104-Rrel but decreased during transition from 104-Rrel to 104-Radp. Expression of genes related to liver X receptor (LXR) signaling changed during progression.

Author(s): 
Chuu, Chih-Pin
Hiipakka, Richard A.
Kokontis, John M.
Fukuchi, Junichi
Chen, Rou-Yu
Liao, Shutsung
Publication Title: 
FASEB journal: official publication of the Federation of American Societies for Experimental Biology

Brassinosteroids are plant-derived polyhydroxylated derivatives of 5a-cholestane, structurally similar to cholesterol-derived animal steroid hormones and insect ecdysteroids, with no known function in mammals. 28-Homobrassinolide (HB), a steroidal lactone with potent plant growth-promoting property, stimulated protein synthesis and inhibited protein degradation in L6 rat skeletal muscle cells (EC(50) 4 μM) mediated in part by PI3K/Akt signaling pathway.

Author(s): 
Esposito, Debora
Komarnytsky, Slavko
Shapses, Sue
Raskin, Ilya
Publication Title: 
Brazilian Oral Research

Osteoporosis, a disease characterized by progressive bone loss, has been the target of several studies in the past few years. It results in a much higher risk for fractures and might cause slower bone lesion healing. The aim of this work was to study the effects of Risedronate (allopathic medicine) and Calcarea phosphorica 6CH (homeopathic medicine) on the repair of bone lesions in male rats with osteoporosis induced by castration. Eighty-four three-month-old rats were used divided into four groups of twenty-one animals each.

Author(s): 
Werkman, Cristina
Senra, Giselle Segnini
da Rocha, Rosilene Fernandes
Brandão, Adriana Aigotti Haberbeck
Publication Title: 
Endocrine Research

The sexual dimorphism of life span and caloric restriction effects in numerous species suggest that estradiol (E2) is protective against oxidative damage. The only direct test of E2's protective effect in mice against in vivo oxidative stress to date may have been confounded by E2's direct chemical action as an antioxidant because it was administered at very high dosages. Therefore, we have identified a low yet physiologically effective dose of E2. We then administered this dose using subcutaneous time-release pellets to ovariectomized mice.

Author(s): 
Bokov, Alex F.
Ko, Daijin
Richardson, Arlan
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

OBJECTIVE: To present a case in which the initial diagnosis of spinal metastasis secondary to prostate cancer was established from findings of the digital rectal examination (DRE) and serum prostate-specific antigen (PSA) analysis. CLINICAL FEATURES: A 79-yr-old black male was seen after suffering from low back pain for 1 month. Urinary frequency and nocturia were associated symptoms. Abnormal findings on the DRE and serum PSA determination suggested a preliminary diagnosis of spinal metastases secondary to prostate cancer.

Author(s): 
Johnson, T. L.

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