Osteoarthritis

Publication Title: 
Current Opinion in Rheumatology

PURPOSE OF REVIEW: This review considers the role of physical therapies in osteoarthritis management, highlighting key findings from systematic reviews and randomized controlled trials published in the last 2 years. RECENT FINDINGS: Three new trials question the role of manual therapy for hip and knee osteoarthritis.

Author(s): 
Bennell, Kim L.
Buchbinder, Rachelle
Hinman, Rana S.
Publication Title: 
Journal of Traditional and Complementary Medicine

To evaluate whether the use of traditional Chinese medicine (TCM; zh?ng y?) influences symptoms or functional outcomes in patients with osteoarthritis (OA) of the knee ( x? gu?n jié yán). A systematic review of randomized control trials was conducted. Searches for studies in PubMed that were performed between 1965 and August 2013, and retrieved studies were subjected to reference screening.

Author(s): 
Hou, Pu-Wei
Fu, Pin-Kuei
Hsu, Hsin-Cheng
Hsieh, Ching-Liang
Publication Title: 
Osteoarthritis and Cartilage

OBJECTIVE: The purpose of this narrative review was to highlight recent research in the rehabilitation of people with osteoarthritis (OA) by summarizing findings from selected key systematic reviews and randomized controlled trials (RCTs). METHODS: A systematic search was conducted using the PubMed, Physiotherapy Evidence Database (PEDro) and Cochrane databases from April 1st 2014 to March 31st 2015. A selection of these is discussed based on study quality, relevance, contribution to new knowledge or controversial findings.

Author(s): 
Bennell, K. L.
Hall, M.
Hinman, R. S.
Publication Title: 
Journal of Ayurveda and Integrative Medicine

The potential of Ayurvedic philosophy and medicines needs to be recognized and converted into real life treatment paradigm. This article describes a comprehensive therapeutic approach used in Ayurveda and modern medicine to treat arthritis. We present concise summary of various controlled drug trials carried out by us to validate standardized Ayurvedic drugs using modern medicine protocol to treat Rheumatoid Arthritis and Osteoarthritis knees. Several of the latter are published.

Author(s): 
Chopra, Arvind
Saluja, Manjit
Tillu, Girish
Publication Title: 
Alternative Medicine Review: A Journal of Clinical Therapeutic

OBJECTIVE: The objective of this paper is to review the literature regarding Withania somnifera (ashwagandha, WS) a commonly used herb in Ayurvedic medicine. Specifically, the literature was reviewed for articles pertaining to chemical properties, therapeutic benefits, and toxicity.

Author(s): 
Mishra, L. C.
Singh, B. B.
Dagenais, S.
Publication Title: 
Rheumatology International

Ayurveda is one of the fastest growing systems within complementary and alternative medicine. However, the evidence for its effectiveness is unsatisfactory. The aim of this work was to review and meta-analyze the effectiveness and safety of different Ayurvedic interventions in patients with osteoarthritis (OA). 138 electronic databases were searched through August 2013. Randomized controlled trials, randomized crossover studies, cluster-randomized trials, and non-randomized controlled clinical trials were eligible. Adults with pre-diagnosed OA were included as participants.

Author(s): 
Kessler, Christian S.
Pinders, Lea
Michalsen, Andreas
Cramer, Holger
Publication Title: 
Ayu

Reported case was a 63-year-old female with end-stage osteoarthritis (OA) (Sandhigata Vata) of the left knee joint accompanied by exostoses. Radiology (X-ray) report confirmed it as a Kellgren-Lawrence grade III or less with exostoses. At the beginning, the Knee Society Rating System scores of pain, movement and stability were poor, and function score was fair. Srilankan traditional and Ayurveda medicine treatment was given in three regimens for 70 days.

Author(s): 
Perera, Pathirage Kamal
Perera, Manaram
Kumarasinghe, Nishantha
Publication Title: 
Nature Genetics

Osteoarthritis is the most common form of arthritis and is a major cause of pain and disability in the elderly. To search for sequence variants that confer risk of osteoarthritis of the hand, we carried out a genome-wide association study (GWAS) in subjects with severe hand osteoarthritis, using variants identified through the whole-genome sequencing of 2,230 Icelanders.

Author(s): 
Styrkarsdottir, Unnur
Thorleifsson, Gudmar
Helgadottir, Hafdis T.
Bomer, Nils
Metrustry, Sarah
Bierma-Zeinstra, S.
Strijbosch, Annelieke M.
Evangelou, Evangelos
Hart, Deborah
Beekman, Marian
Jonasdottir, Aslaug
Sigurdsson, Asgeir
Eiriksson, Finnur F.
Thorsteinsdottir, Margret
Frigge, Michael L.
Kong, Augustine
Gudjonsson, Sigurjon A.
Magnusson, Olafur T.
Masson, Gisli
TREAT-OA Consortium
arcOGEN Consortium
Hofman, Albert
Arden, Nigel K.
Ingvarsson, Thorvaldur
Lohmander, Stefan
Kloppenburg, Margreet
Rivadeneira, Fernando
Nelissen, Rob G. H. H.
Spector, Tim
Uitterlinden, Andre
Slagboom, P. Eline
Thorsteinsdottir, Unnur
Jonsdottir, Ingileif
Valdes, Ana M.
Meulenbelt, Ingrid
van Meurs, Joyce
Jonsson, Helgi
Stefansson, Kari
Publication Title: 
The Proceedings of the Nutrition Society

Companion animals represent an under-utilised resource. The present paper is designed to encourage collaborative studies. Dogs and cats are out-bred animals that are willing to consume a consistent diet for long periods, so are ideal candidates for prospective studies of naturally-occurring disease. In some studies the effect of diet on survival has been substantial.

Author(s): 
Hill, Richard C.
Publication Title: 
Journal of Aging and Physical Activity

Exercise self-efficacy is a powerful predictor of physical activity behavior, which enhances health and well-being for older adults. Social relations have been proposed as influential precursors for exercise self-efficacy. In a longitudinal study of 160 older adults with osteoarthritis (76.9% women), the authors found that social support (but not social strain) significantly predicted exercise self-efficacy in a structural equation model examining cross-sectional data: chi(2) (178, N = 160) = 264.57, p < .01; RMSEA = .06; CFI = .92; TLI = .90.

Author(s): 
Cotter, Kelly A.
Sherman, Aurora M.

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