Pain Perception

Publication Title: 
Physiotherapy Theory and Practice

The aim of this manuscript was to investigate the effectiveness of conservative therapy for phantom limb pain (PLP). In this systematic review, CINAHL, AMED, the Cochrane database of systematic reviews, PEDro, psychology and behavioral sciences collection, and MEDLINE were systematically searched for appropriate randomized controlled trials (RCTs). Selected papers were assessed for risk of bias, and evidence was graded using the GRADE approach. Twelve RCTs met initial inclusion/exclusion criteria, of which five were of sufficient quality for final inclusion.

Batsford, Sarah
Ryan, Cormac G.
Martin, Denis J.
Publication Title: 
Journal of Physiology, Paris

BACKGROUND AND OBJECTIVE: Several studies reported that hypnosis can modulate pain perception and tolerance by affecting cortical and subcortical activity in brain regions involved in these processes. We conducted an Activation Likelihood Estimation (ALE) meta-analysis on functional neuroimaging studies of pain perception under hypnosis to identify brain activation-deactivation patterns occurring during hypnotic suggestions aiming at pain reduction, including hypnotic analgesic, pleasant, or depersonalization suggestions (HASs).

Del Casale, Antonio
Ferracuti, Stefano
Rapinesi, Chiara
De Rossi, Pietro
Angeletti, Gloria
Sani, Gabriele
Kotzalidis, Georgios D.
Girardi, Paolo
Publication Title: 
PloS One

Empathy allows us to understand and react to other people's feelings and sensations; we can more accurately judge another person's situation when we are aware of his/her emotions. Empathy for pain is a good working model of the behavioral and neural processes involved in empathy in general. Although the influence of perspective-taking processes (notably "Self" vs. "Other") on pain rating has been studied, the impact of the degree of familiarity with the person representing the "Other" perspective has not been previously addressed.

Bucchioni, Giulia
Lelard, Thierry
Ahmaidi, Said
Godefroy, Olivier
Krystkowiak, Pierre
Mouras, Harold
Publication Title: 

Hypnosis modulates pain perception but the associated brain mechanisms in chronic pain conditions are poorly understood. Brain activity evoked by painful repetitive pin-prick stimulation of the left mental nerve region was investigated with use of fMRI in 19 patients with painful temporomandibular disorders (TMD) during hypnotic hypoalgesia and hyperalgesia and a control condition. Pain intensity and unpleasantness of the painful stimulation was scored on a 0-10 Numerical Rating Scale (NRS).

Abrahamsen, Randi
Dietz, Martin
Lodahl, Sanne
Roepstorff, Andreas
Zachariae, Robert
Østergaard, Leif
Svensson, Peter
Publication Title: 
PloS One

Implementing a recall paradigm without hypnosis, we use functional MRI (fMRI) to explore and compare nociceptive and centrally-driven pain experiences. We posit that a trace of a recent nociceptive event can be used to create sensory-re-experiencing of pain that can be qualified in terms of intensity and vividness. Fifteen healthy volunteers received three levels of thermal stimuli (warm, low pain and high pain) and subsequently were asked to recall and then rate this experience.

Fairhurst, Merle
Fairhurst, Katherine
Berna, Chantal
Tracey, Irene
Publication Title: 
Neurophysiologie Clinique = Clinical Neurophysiology

We here review behavioral, neuroimaging and electrophysiological studies of hypnosis as a state, as well as hypnosis as a tool to modulate brain responses to painful stimulations. Studies have shown that hypnotic processes modify internal (self awareness) as well as external (environmental awareness) brain networks. Brain mechanisms underlying the modulation of pain perception under hypnotic conditions involve cortical as well as subcortical areas including anterior cingulate and prefrontal cortices, basal ganglia and thalami.

Vanhaudenhuyse, A.
Laureys, S.
Faymonville, M.-E.
Publication Title: 
Pain Medicine (Malden, Mass.)

OBJECTIVE: Mixed evidence exists regarding whether irritable bowel syndrome (IBS) patients show increased somatic pain perception compared with controls. The current study used a deep, tonic somatic pain stimulus (ischemic pain) to evaluate somatic hypersensitivity in IBS patients. METHODS: A total of 27 diarrhea-predominant and 15 constipation-predominant IBS patients, and 29 controls participated in the study.

Zhou, QiQi
Fillingim, Roger B.
Riley, Joseph L.
Verne, G. Nicholas
Publication Title: 
Molecular Pain

BACKGROUND: Electroacupuncture (EA) is currently one of the most popular acupuncture modalities. However, the continuous stimulation characteristic of EA treatment presents challenges to the use of conventional functional Magnetic Resonance Imaging (fMRI) approaches for the investigation of neural mechanisms mediating treatment response because of the requirement for brief and intermittent stimuli in event related or block designed task paradigms.

Zyloney, Carolyn E.
Jensen, Karin
Polich, Ginger
Loiotile, Rita E.
Cheetham, Alexandra
LaViolette, Peter S.
Tu, Peichi
Kaptchuk, Ted J.
Gollub, Randy L.
Kong, Jian
Publication Title: 
Journal of Electromyography and Kinesiology: Official Journal of the International Society of Electrophysiological Kinesiology

Spinal manipulation (SMT) is commonly used for treating individuals experiencing musculoskeletal pain. The mechanisms of SMT remain unclear; however, pain sensitivity testing may provide insight into these mechanisms. The purpose of this systematic review is to examine the literature on the hypoalgesic effects of SMT on pain sensitivity measures and to quantify these effects using meta-analysis. We performed a systematic search of articles using CINAHL, MEDLINE, PsycINFO, and SPORTDiscus from each databases' inception until May 2011.

Coronado, Rogelio A.
Gay, Charles W.
Bialosky, Joel E.
Carnaby, Giselle D.
Bishop, Mark D.
George, Steven Z.
Publication Title: 
The Clinical Journal of Pain

OBJECTIVES: We propose a theoretical framework for the behavioral modulation of pain based on constructivism, positing that task engagement, such as listening for errors in a musical passage, can establish a construction of reality that effectively replaces pain as a competing construction. Graded engagement produces graded reductions in pain as indicated by reduced psychophysiological arousal and subjective pain report.

Bradshaw, David H.
Chapman, C. Richard
Jacobson, Robert C.
Donaldson, Gary W.


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