Pattern Recognition, Automated

Publication Title: 
Scientific Reports

Assessment of hypnotic susceptibility is usually obtained through the application of psychological instruments. A satisfying classification obtained through quantitative measures is still missing, although it would be very useful for both diagnostic and clinical purposes. Aiming at investigating the relationship between the cortical brain activity and the hypnotic susceptibility level, we propose the combined use of two methodologies - Recurrence Quantification Analysis and Detrended Fluctuation Analysis - both inherited from nonlinear dynamics.

Author(s): 
Chiarucci, Riccardo
Madeo, Dario
Loffredo, Maria I.
Castellani, Eleonora
Santarcangelo, Enrica L.
Mocenni, Chiara
Publication Title: 
Journal of Chromatography. A

Traditional Chinese Herbal Medicine (TCHM) contain multiple botanicals, each of which contains many compounds that may be relevant to the medicine's putative activity. Therefore, analytical techniques that look at a suite of compounds, including their respective ratios, provide a more rational approach to the authentication and quality assessment of TCHM.

Author(s): 
Xie, Peishan
Chen, Sibao
Liang, Yi-Zeng
Wang, Xianghong
Tian, Runtao
Upton, Roy
Publication Title: 
IEEE transactions on cybernetics

Discriminating altruism, particularly kin altruism, is a fundamental mechanism of cooperation in nature. Altruistic behavior is not favored by evolution in the circumstances where there are "kin cheaters" that cannot be effectively identified. Using evolutionary iterated prisoner's dilemma, we deduce the condition for discriminating strategies to be evolutionarily stable and show that the competition between groups of different discriminating strategies restrains the percentage of kin cheaters.

Author(s): 
Li, Jiawei
Kendall, Graham
Publication Title: 
Conference proceedings: ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

Research has demonstrated the efficacy of closed-loop control of anesthesia using bispectral index (BIS) as the controlled variable, and the recent development of model-based, patient-adaptive systems has considerably improved anesthetic control. To further explore the use of model-based control in anesthesia, we investigated the application of fuzzy control in the delivery of patient-specific propofol-induced hypnosis. In simulated intraoperative patients, the fuzzy controller demonstrated clinically acceptable performance, suggesting that further study is warranted.

Author(s): 
Moore, Brett L.
Pyeatt, Larry D.
Doufas, Anthony G.
Publication Title: 
Anesthesia and Analgesia

BACKGROUND: Research has demonstrated the efficacy of closed-loop control of anesthesia using bispectral index (BIS) as the controlled variable. Model-based and proportional-integral-derivative (PID) controllers outperform manual control. We investigated the application of reinforcement learning (RL), an intelligent systems control method, to closed-loop BIS-guided, propofol-induced hypnosis in simulated intraoperative patients. We also compared the performance of the RL agent against that of a conventional PID controller.

Author(s): 
Moore, Brett L.
Quasny, Todd M.
Doufas, Anthony G.
Publication Title: 
Anesthesia and Analgesia

Reinforcement learning (RL) is an intelligent systems technique with a history of success in difficult robotic control problems. Similar machine learning techniques, such as artificial neural networks and fuzzy logic, have been successfully applied to clinical control problems. Although RL presents a mathematically robust method of achieving optimal control in systems challenged with noise, nonlinearity, time delay, and uncertainty, no application of RL in clinical anesthesia has been reported.

Author(s): 
Moore, Brett L.
Doufas, Anthony G.
Pyeatt, Larry D.
Publication Title: 
Conference proceedings: ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

In the diagnosis and treatment of epilepsy, long-term monitoring may be required to document and study interictal activities such as interictal spikes. However, visual inspection of the EEG done by an expert is too time consuming and researchers normally resort to automatic detection methods. We describe a new EEG user-guided interictal spike detection algorithm that only requires the user to annotate a few spikes.

Author(s): 
El-Gohary, Mahmoud
McNames, James
Elsas, Siegward
Publication Title: 
NeuroImage

The perirhinal cortex (Brodmann's area 35) is a multimodal area that is important for normal memory function. Specifically, perirhinal cortex is involved in the detection of novel objects and manifests neurofibrillary tangles in Alzheimer's disease very early in disease progression. We scanned ex vivo brain hemispheres at standard resolution (1 mm × 1 mm × 1 mm) to construct pial/white matter surfaces in FreeSurfer and scanned again at high resolution (120 μm × 120 μm × 120 μm) to determine cortical architectural boundaries.

Author(s): 
Augustinack, Jean C.
Huber, Kristen E.
Stevens, Allison A.
Roy, Michelle
Frosch, Matthew P.
van der Kouwe, André J. W.
Wald, Lawrence L.
Van Leemput, Koen
McKee, Ann C.
Fischl, Bruce
Alzheimer's Disease Neuroimaging Initiative
Publication Title: 
Medical image computing and computer-assisted intervention: MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

Availability of multi-modal magnetic resonance imaging (MRI) databases opens up the opportunity to synthesize different MRI contrasts without actually acquiring the images. In theory such synthetic images have the potential to reduce the amount of acquisitions to perform certain analyses. However, to what extent they can substitute real acquisitions in the respective analyses is an open question. In this study, we used a synthesis method based on patch matching to test whether synthetic images can be useful in segmentation and inter-modality cross-subject registration of brain MRI.

Author(s): 
Iglesias, Juan Eugenio
Konukoglu, Ender
Zikic, Darko
Glocker, Ben
Van Leemput, Koen
Fischl, Bruce
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

Chiropractic analysis often incorporates the evaluation of heat distribution patterns observed in skin temperature profiles. Historically, temperature recordings of the spine have been made with a heat detection instrument using a thermocouple design. The advent of refinements in infrared technology, however, have greatly enhanced temperature detection in terms of accuracy and reliability. The present research reflects the development of computer software designed to express the data obtained with a dual channel heat sensing instrument.

Author(s): 
Stewart, M. S.
Riffle, D. W.
Boone, W. R.

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