Peripheral Arterial Disease

Publication Title: 
PloS One

Research supports the use of supervised exercise training as a primary therapy for improving the functional status of people with peripheral arterial disease (PAD). Several reviews have focused on reporting the outcomes of exercise interventions, but none have critically examined the quality of intervention reporting. Adequate reporting of the exercise protocols used in randomised controlled trials (RCTs) is central to interpreting study findings and translating effective interventions into practice.

Author(s): 
Tew, Garry A.
Brabyn, Sally
Cook, Liz
Peckham, Emily
Publication Title: 
Biomedical and environmental sciences: BES

Major and profound changes have taken place in China over the past 30 years. Rapid socioeconomic progress has exerted a great impact on lifestyle, ranging from food, clothing, working and living conditions, and means of transportation to leisure activities and entertainment. At the same time, new health problems have emerged, and health services are facing new challenges. Presently, cardiovascular diseases (CVD) are among the top health problems of the Chinese people, and pose a serious challenge to all engaged in the prevention and control of these diseases.

Author(s): 
Hu, Sheng Shou
Kong, Ling Zhi
Gao, Run Lin
Zhu, Man Lu
Wang, Wen
Wang, Yong Jun
Wu, Zhao Su
Chen, Wei Wei
Liu, Ming Bo
Editorial Board
Publication Title: 
Atherosclerosis

BACKGROUND: Peripheral artery disease (PAD) is a debilitating condition involving atherosclerosis. Although saturated, monounsaturated and polyunsaturated fatty acids have strong associations with atherosclerosis, it is unclear if diets high in these fatty acids affect PAD. METHODS: We studied 6352 adults aged 40 years and older who participated in the U.S. National Health and Nutrition Examination Survey between 1999 and 2004. Ankle brachial index (ABI) was assessed by standardized blood pressure measurements, and we defined PAD as an ABI<0.9.

Author(s): 
Naqvi, Asghar Z.
Davis, Roger B.
Mukamal, Kenneth J.
Publication Title: 
Angiology

We compared apoptosis, cellular oxidative stress, and inflammation of cultured endothelial cells treated with sera from 130 patients with peripheral artery disease (PAD) and a control group of 36 patients with high burden of comorbid conditions and cardiovascular risk factors. Second, we compared circulating inflammatory, antioxidant capacity, and vascular biomarkers between the groups. The groups were not significantly different (P > .05) on apoptosis, hydrogen peroxide, hydroxyl radical antioxidant capacity, and nuclear factor κ-light-chain enhancer of activated B cells.

Author(s): 
Gardner, Andrew W.
Parker, Donald E.
Montgomery, Polly S.
Sosnowska, Danuta
Casanegra, Ana I.
Esponda, Omar L.
Ungvari, Zoltan
Csiszar, Anna
Sonntag, William E.
Publication Title: 
Vascular

Substantial lower-limb edema affects the majority of patients who undergo peripheral bypass surgery. Edema has impairing effects on the microvascular and the macrovascular circulation, causes discomfort and might delay the rehabilitation process of the patient. However, the pathophysiology of this edema is not well understood. The Cochrane Library and Medline were used to retrieve literature on edema following peripheral bypass surgery. Factors other than local wound healing alone are suggested in the literature to play a role, given the severity and duration of this edema.

Author(s): 
te Slaa, A.
Dolmans, D. E. J. G. J.
Ho, G. H.
Moll, F. L.
van der Laan, L.
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