Phosphinic Acids

Publication Title: 

RATIONALE: A recent in-vitro study demonstrated that the potent disulfide reducing agent, DL-dithiothreitol (DTT), may alter the structural stability of the GABA(B) receptor, probably inactivating the disulfide bonds between four cysteine residues located in the GABA(B1(a)) receptor structure. OBJECTIVES: The present study was designed to evaluate whether DTT treatment was capable of antagonizing some behavioral effects of pharmacological stimulation of the GABA(B) receptor.

Carai, Mauro A. M.
Vacca, Giovanni
Serra, Salvatore
Colombo, Giancarlo
Froestl, Wolfgang
Gessa, Gian Luigi
Subscribe to RSS - Phosphinic Acids