Powders

Publication Title: 
Regulatory toxicology and pharmacology: RTP

Ginger (Zingiber officinale Roscoe, Zingiberacae) is one of the most commonly used spices around the world and a traditional medicinal plant that has been widely used in Chinese, Ayurvedic and Unani-Tibb medicines for several thousand years. However, there was still lack of systemic safety evaluation. We conducted a 35-day toxicity study on ginger in rats. Both male and female rats were daily treated with ginger powder at the dosages of 500, 1000 and 2000 mg/kg body weight by a gavage method for 35 days.

Author(s): 
Rong, Xianglu
Peng, Gang
Suzuki, Takuya
Yang, Qinglin
Yamahara, Johji
Li, Yuhao
Publication Title: 
African journal of traditional, complementary, and alternative medicines: AJTCAM / African Networks on Ethnomedicines

Validated modified lycopodium spore method has been developed for simple and rapid quantification of herbal powdered drugs. Lycopodium spore method was performed on ingredients of Shatavaryadi churna, an ayurvedic formulation used as immunomodulator, galactagogue, aphrodisiac and rejuvenator. Estimation of diagnostic characters of each ingredient of Shatavaryadi churna individually was carried out. Microscopic determination, counting of identifying number, measurement of area, length and breadth of identifying characters were performed using Leica DMLS-2 microscope.

Author(s): 
Kumar, Puspendra
Jha, Shivesh
Naved, Tanveer
Publication Title: 
Journal of Ethnopharmacology

The effects of Abana, an Ayurvedic remedy, administered orally to rabbits was studied for its effects on isolated atria and intestine. Administration of Abana for 3 days increased the basal amplitude and reduced the responses of atria to isoprenaline and norepinephrine. Combined treatment with Abana and isoprenaline reduced this effect. It is possible that Abana treatment for 3 days has an action similar to that of chronic administration of isoprenaline (down regulation of beta receptors). A similar down regulation of beta receptors of smooth muscle of rabbit intestine also seems to occur.

Author(s): 
Pasnani, J. S.
Hemavathi, K. G.
Gulati, O. D.
Rajani, A. P.
Publication Title: 
Vascular Pharmacology

In the present study, we have investigated the efficacy of Indian ayurvedic herbal formulation Triphala on monosodium urate crystal-induced inflammation in mice; an experimental model for gouty arthritis and compared it with that of the non-steroidal anti-inflammatory drug, Indomethacin. The anti-arthritic effect of Triphala was evaluated by measuring changes in the paw volume, lysosomal enzyme activities, lipid peroxidation, anti-oxidant status and inflammatory mediator TNF-alpha in control and monosodium urate crystal-induced mice.

Author(s): 
Sabina, E. P.
Rasool, M.
Publication Title: 
Regulatory toxicology and pharmacology: RTP

Ginger (Zingiber officinale Roscoe, Zingiberacae) is one of the most commonly used spices around the world and a traditional medicinal plant that has been widely used in Chinese, Ayurvedic and Unani-Tibb medicines for several thousand years. However, there was still lack of systemic safety evaluation. We conducted a 35-day toxicity study on ginger in rats. Both male and female rats were daily treated with ginger powder at the dosages of 500, 1000 and 2000 mg/kg body weight by a gavage method for 35 days.

Author(s): 
Rong, Xianglu
Peng, Gang
Suzuki, Takuya
Yang, Qinglin
Yamahara, Johji
Li, Yuhao
Publication Title: 
Journal of Basic and Clinical Physiology and Pharmacology

We investigated the protective effect of Withania somnifera root powder (used in ayurvedic medicine in India) on gentamicin (GEN) induced nephrotoxicity in male Wistar rats. The root powder was administered orally to rats for 14 days before GEN treatment and thereafter with GEN for 8 days.

Author(s): 
Jeyanthi, Thangavel
Subramanian, Perumal
Publication Title: 
Phytomedicine: International Journal of Phytotherapy and Phytopharmacology

Bacopa monnieri (BM) an herb, found throughout the Indian subcontinent in wet, damp and marshy areas is used in Ayurvedic system of medicine for improving intellect/memory, treatment of anxiety and neuropharmacological disorders. Although extensively given to children as a memory enhancer, no data exists on its ability to modulate neuronal oxidative stress in prepubertal animal models.

Author(s): 
Shinomol, George K.
Muralidhara, null
Publication Title: 
Pharmaceutical Biology

CONTEXT: Withania somnifera (Linn.) Dunal (Solanaceae) has long been used as an herb in Ayurvedic and indigenous medicine and has received intense attention in recent years for its chemopreventive properties. OBJECTIVE: The present study focuses on the effect of W. somnifera root powder on the behavioral and radiological changes in collagen-induced arthritic rats. MATERIALS AND METHODS: The rats were randomly divided into five groups: normal control, arthritic control, arthritic rats treated with W.

Author(s): 
Gupta, Apurva
Singh, Surendra
Publication Title: 
African journal of traditional, complementary, and alternative medicines: AJTCAM / African Networks on Ethnomedicines

Validated modified lycopodium spore method has been developed for simple and rapid quantification of herbal powdered drugs. Lycopodium spore method was performed on ingredients of Shatavaryadi churna, an ayurvedic formulation used as immunomodulator, galactagogue, aphrodisiac and rejuvenator. Estimation of diagnostic characters of each ingredient of Shatavaryadi churna individually was carried out. Microscopic determination, counting of identifying number, measurement of area, length and breadth of identifying characters were performed using Leica DMLS-2 microscope.

Author(s): 
Kumar, Puspendra
Jha, Shivesh
Naved, Tanveer
Publication Title: 
Forschende Komplementärmedizin (2006)

BACKGROUND: According to traditional European naturopathy garlic is an agent that increases perfusion. In studies with healthy subjects and in-vitro research garlic has shown influences on erythrocyte and thrombocyte aggregation as well as on vasoregulation. However, data on its effects in clinical populations are still lacking. Garlic may be useful for systemic sclerosis which is characterised by impaired perfusion that often cannot sufficiently be influenced by standard treatment.

Author(s): 
Rapp, Alexander
Grohmann, Gerald
Oelzner, Peter
Uehleke, Bernhard
Uhlemann, Christine

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