Predictive Value of Tests

Publication Title: 
Acta Cytologica

ISSUES: Optical digital imaging and its related technologies have applications in cytopathology that encompass training and education, image analysis, diagnosis, report documentation and archiving, and telecommunications. Telecytology involves the use of telecommunications to transmit cytology images for the purposes of diagnosis, consultation or education.

Author(s): 
O'Brien, M. J.
Takahashi, M.
Brugal, G.
Christen, H.
Gahm, T.
Goodell, R. M.
Karakitsos, P.
Knesel, E. A.
Kobler, T.
Kyrkou, K. A.
Labbe, S.
Long, E. L.
Mango, L. J.
McGoogan, E.
Oberholzer, M.
Reith, A.
Winkler, C.
Publication Title: 
Current Medical Research and Opinion

OBJECTIVE: This review addresses the relationship between attention-deficit/hyperactivity disorder (ADHD) and substance use disorders (SUDs), with an emphasis on factors that determine the potential for psychostimulant abuse. Strategies for identification and treatment of patients with ADHD who are at risk for, or have, co-morbid SUD are also addressed. RESEARCH DESIGN AND METHODS: The article was based on a qualitative review of current literature addressing co-morbid ADHD and SUD.

Author(s): 
Kollins, Scott H.
Publication Title: 
Journal of Gastroenterology and Hepatology

Irritable bowel syndrome (IBS), a chronic gastrointestinal disorder, affects from 3-20% of the US population, depending on sociocultural and comorbid factors. IBS is characterized by a symptom complex of abdominal pain and abnormal bowel habits that present as diarrhea or constipation, and general physical weakness in the absence of abnormal morphological, histological or inflammatory markers. The main diagnostic Rome III criteria as established by international professional organizations are based on exclusion criteria and the occurrence and rate of symptoms.

Author(s): 
Grundmann, Oliver
Yoon, Saunjoo L.
Publication Title: 
Journal of Gastroenterology and Hepatology

Irritable bowel syndrome (IBS), a chronic gastrointestinal disorder, affects from 3-20% of the US population, depending on sociocultural and comorbid factors. IBS is characterized by a symptom complex of abdominal pain and abnormal bowel habits that present as diarrhea or constipation, and general physical weakness in the absence of abnormal morphological, histological or inflammatory markers. The main diagnostic Rome III criteria as established by international professional organizations are based on exclusion criteria and the occurrence and rate of symptoms.

Author(s): 
Grundmann, Oliver
Yoon, Saunjoo L.
Publication Title: 
Asia Pacific Journal of Clinical Nutrition

To identify protective dietary predictors amongst long-lived elderly people (N= 785), the "Food Habits in Later Life "(FHILL) study was undertaken among five cohorts in Japan, Sweden, Greece and Australia. Between 1988 and 1991, baseline data on food intakes were collected. There were 785 participants aged 70 and over that were followed up to seven years.

Author(s): 
Darmadi-Blackberry, Irene
Wahlqvist, Mark L.
Kouris-Blazos, Antigone
Steen, Bertil
Lukito, Widjaja
Horie, Yoshimitsu
Horie, Kazuyo
Publication Title: 
The Journal of Thoracic and Cardiovascular Surgery

OBJECTIVE: With the increasing longevity of heart transplant recipients, the long-term effects of cyclosporine on renal function have become more evident. Highly sensitive, early, and effective monitoring of posttransplant renal function is still being researched. This study aimed to evaluate the prognostic value of cystatin C for patients after heart transplantation. METHODS: Seventy-three long-term recipients of a heart transplant more than 5 years before the study start were included in the analysis with a follow-up of 4 years.

Author(s): 
Kniepeiss, Daniela
Wagner, Doris
Wirnsberger, Gerhard
Roller, Regina E.
Wasler, Andr‰
Iberer, Florian
Tscheliessnigg, Karl-Heinz
Publication Title: 
Molecular Psychiatry

Telomeres are DNA-protein complexes that cap linear DNA strands, protecting DNA from damage. When telomeres critically shorten, cells become susceptible to senescence and apoptosis. Telomerase, a cellular ribonucleoprotein enzyme, rebuilds the length of telomeres and promotes cellular viability. Leukocyte telomeres are reportedly shortened in major depression, but telomerase activity in depression has not been previously reported.

Author(s): 
Wolkowitz, O. M.
Mellon, S. H.
Epel, E. S.
Lin, J.
Reus, V. I.
Rosser, R.
Burke, H.
Compagnone, M.
Nelson, J. C.
Dhabhar, F. S.
Blackburn, E. H.
Publication Title: 
The Journal of Bone and Joint Surgery. American Volume

BACKGROUND: The experience of undergoing surgery is known to induce a short-term, fight-or-flight physiological stress response. As an optimum immune response at the site of surgery would enhance tissue repair, we examined surgical stress-induced immune cell redistribution profiles as predictors, and potential mediators, of short and long-term postoperative recovery. We tested the a priori hypothesis that predefined adaptive immune cell redistribution profiles observed during surgery will predict enhanced postoperative recovery.

Author(s): 
Rosenberger, Patricia H.
Ickovics, Jeannette R.
Epel, Elissa
Nadler, Eric
Jokl, Peter
Fulkerson, John P.
Tillie, Jean M.
Dhabhar, Firdaus S.
Publication Title: 
Molecular Psychiatry

Telomeres are DNA-protein complexes that cap linear DNA strands, protecting DNA from damage. When telomeres critically shorten, cells become susceptible to senescence and apoptosis. Telomerase, a cellular ribonucleoprotein enzyme, rebuilds the length of telomeres and promotes cellular viability. Leukocyte telomeres are reportedly shortened in major depression, but telomerase activity in depression has not been previously reported.

Author(s): 
Wolkowitz, O. M.
Mellon, S. H.
Epel, E. S.
Lin, J.
Reus, V. I.
Rosser, R.
Burke, H.
Compagnone, M.
Nelson, J. C.
Dhabhar, F. S.
Blackburn, E. H.
Publication Title: 
International Journal of Legal Medicine

Clinical risk factors have a low predictive value on suicide. This may explain the increasing interest in potential neurobiological correlates and specific heritable markers of suicide vulnerability. This review aims to present the current neurobiological findings that have been shown to be implicated in suicide completers and to discuss how postmortem studies may be useful in characterizing these individuals.

Author(s): 
Costanza, Alessandra
D'Orta, Isabella
Perroud, Nader
Burkhardt, Sandra
Malafosse, Alain
Mangin, Patrice
La Harpe, Romano

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