Pyrogallol

Publication Title: 
Medicinal Chemistry (Shariqah (United Arab Emirates))

Ethanolic extracts of 30 Thai medicinal plants, traditionally used as alternative treatments in diabetes, were evaluated for antioxidative activity by the 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) method. They were evaluated in vitro for oxidative stress by thiobarbituric acid-reactive substance (TBARS) assay in pooled plasma of diabetic patients compared to without treatment of the extracts (control). The extracts were also assayed for protein glycation. The results showed that five plants had strong antioxidant activity: Phyllanthus emblica Linn.

Author(s): 
Kusirisin, W.
Srichairatanakool, S.
Lerttrakarnnon, P.
Lailerd, N.
Suttajit, M.
Jaikang, C.
Chaiyasut, C.
Publication Title: 
Pharmacognosy Research

BACKGROUND: Terminalia chebula is called the "king of medicines" in Tibet and is always listed first in the Ayurvedic meteria medica because of its extraordinary powers of healing. OBJECTIVE: Identification, isolation and screening of pyrogallol which are responsible for antimicrobial property of fruits of Terminalia chebula. MATERIALS AND METHODS: Ethyl acetate fraction of fruits of Terminalia chebula was subjected to Gas chromatography-mass spectrometry (GC-MS) for the components present in the extract.

Author(s): 
Singh, Geeta
Kumar, Padma
Publication Title: 
Phytomedicine: International Journal of Phytotherapy and Phytopharmacology

Hemidesmus indicus R. Br. (Asclepiadaceae) is a well known drug in Ayurveda system of medicine. In the present study, antioxidant activity of methanolic extract of H. indicus root bark was evaluated in several in vitro and ex vivo models. Further, preliminary phytochemical analysis and TLC fingerprint profile of the extract was established to characterize the extract which showed antioxidant properties. The in vitro and ex vivo antioxidant potential of root bark of H. indicus was evaluated in different systems viz.

Author(s): 
Ravishankara, M. N.
Shrivastava, Neeta
Padh, Harish
Rajani, M.
Publication Title: 
Japanese Journal of Pharmacology

Mace which is the aril of the fruit of Myristica fragrans HOUTT, has been used in Indonesian folk medicine as aromatic stomachics, analgesics, a medicine for rheumatism, etc. The present study was carried out to elucidate the antiinflammatory effect of methanol extract obtained from Mace and its active principles. The methanol extract was extracted with ether, and then the ether soluble fraction was extracted with n-hexane.

Author(s): 
Ozaki, Y.
Soedigdo, S.
Wattimena, Y. R.
Suganda, A. G.
Publication Title: 
Molecules (Basel, Switzerland)

Hypochlorite is a strong oxidant able to induce deleterious effects in biological systems. The goal of this work was to investigate the use of PGR and PYR as probes in assays aimed at evaluating antioxidant activities towards hypochorite and apply it to plant extracts employed in Chilean folk medicine. The consumption of PGR and PYR was evaluated from the decrease in the visible absorbance and fluorescence intensity, respectively. Total phenolic content was determined by the Folin Ciocalteau assay.

Author(s): 
Pérez-Cruz, Fernanda
Cortés, Contanza
Atala, Elias
Bohle, Pamela
Valenzuela, Francisco
Olea-Azar, Claudio
Speisky, Hernán
Aspée, Alexis
Lissi, Eduardo
López-Alarcón, Camilo
Bridi, Raquel
Publication Title: 
Chemical & Pharmaceutical Bulletin

The fingerprint technique has been studied frequently as a useful strategy for quality of traditional Chinese medicine. A novel potency fingerprint that can quantitatively analyze the antioxidant activity of individual constituent and provide the total antioxidant activities of the samples has been developed by high-performance liquid chromatography coupled with ultraviolet and pyrogallol-luminol chemiluminescence detection (HPLC-diode array detection (DAD)-PLD).

Author(s): 
Chang, Yan-Xu
Yan, Dong-Mei
Chen, Lin-Lin
Ding, Xiao-Ping
Qi, Jin
Kang, Li-Yuan
Zhang, Bo-li
Yu, Bo-Yang
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