Rats, Nude

Publication Title: 
International Journal of Radiation Oncology, Biology, Physics

PURPOSE: We investigated the effects of fractionated radiation treatments on the life spans of athymic rats bearing intracerebral brain tumors. METHODS AND MATERIALS: U-251 MG or U-87 MG human glioblastoma cells were implanted into the brains of athymic rats, and the resulting tumors were irradiated once daily with various doses of ionizing radiation for 5 consecutive days or for 10 days with a 2-day break after Day 5. RESULTS: Five daily doses of 1 and 1.5 Gy, and 10 doses of 0.75 and 1 Gy, cured some U-251 MG tumors.

Author(s): 
Ozawa, Tomoko
Faddegon, Bruce A.
Hu, Lily J.
Bollen, Andrew W.
Lamborn, Kathleen R.
Deen, Dennis F.
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