Reproducibility of Results

Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Evidence suggests yoga is a safe and effective intervention for the management of physical and psychosocial symptoms associated with musculoskeletal conditions. However, heterogeneity in the components and reporting of clinical yoga trials impedes both the generalization of study results and the replication of study protocols. The aim of this Delphi survey was to address these issues of heterogeneity, by developing a list of recommendations of key components for the design and reporting of yoga interventions for musculoskeletal conditions.

Author(s): 
Ward, Lesley
Stebbings, Simon
Sherman, Karen J.
Cherkin, Daniel
Baxter, G. David
Publication Title: 
Journal of Community Health

The purpose of this study was to identify the perceptions of nurses toward the effectiveness and safety, as well as their recommendations for and personal use of complementary and alternative medical therapies. A, random sample of 1000 nurses throughout the United States were surveyed using a three-wave mailing. About half of the respondents perceived there was conclusive evidence or preponderance of evidence that five therapies were effective: biofeedback, chiropractic, meditation/relaxation, multi-vitamins, and massage therapy.

Author(s): 
Brolinson, P. G.
Price, J. H.
Ditmyer, M.
Reis, D.
Publication Title: 
Journal of the American Pharmacists Association: JAPhA

OBJECTIVE: To assess actions of community pharmacists in response to their patients' concurrent use of prescription medications and complementary and alternative medicine (CAM). DESIGN: Nonexperimental, cross-sectional mail survey. SETTING: Texas. PARTICIPANTS: 107 community pharmacists. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Pharmacists' self-reported rate of patient inquiry about CAM use and actions taken in response to CAM use.

Author(s): 
Brown, Carolyn M.
Barner, Jamie C.
Shah, Sonalee
Publication Title: 
Psychological Bulletin

We report the results of meta-analyses on 3 types of free-response study: (a) ganzfeld (a technique that enhances a communication anomaly referred to as "psi"); (b) nonganzfeld noise reduction using alleged psi-enhancing techniques such as dream psi, meditation, relaxation, or hypnosis; and (c) standard free response (nonganzfeld, no noise reduction). For the period 1997-2008, a homogeneous data set of 29 ganzfeld studies yielded a mean effect size of 0.142 (Stouffer Z = 5.48, p = 2.13 x 10(-8)).

Author(s): 
Storm, Lance
Tressoldi, Patrizio E.
Di Risio, Lorenzo
Publication Title: 
Journal of Community Health

The purpose of this study was to identify the perceptions of nurses toward the effectiveness and safety, as well as their recommendations for and personal use of complementary and alternative medical therapies. A, random sample of 1000 nurses throughout the United States were surveyed using a three-wave mailing. About half of the respondents perceived there was conclusive evidence or preponderance of evidence that five therapies were effective: biofeedback, chiropractic, meditation/relaxation, multi-vitamins, and massage therapy.

Author(s): 
Brolinson, P. G.
Price, J. H.
Ditmyer, M.
Reis, D.
Publication Title: 
Journal of the American Pharmacists Association: JAPhA

OBJECTIVE: To assess actions of community pharmacists in response to their patients' concurrent use of prescription medications and complementary and alternative medicine (CAM). DESIGN: Nonexperimental, cross-sectional mail survey. SETTING: Texas. PARTICIPANTS: 107 community pharmacists. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Pharmacists' self-reported rate of patient inquiry about CAM use and actions taken in response to CAM use.

Author(s): 
Brown, Carolyn M.
Barner, Jamie C.
Shah, Sonalee
Publication Title: 
Acta Cytologica

ISSUES: Optical digital imaging and its related technologies have applications in cytopathology that encompass training and education, image analysis, diagnosis, report documentation and archiving, and telecommunications. Telecytology involves the use of telecommunications to transmit cytology images for the purposes of diagnosis, consultation or education.

Author(s): 
O'Brien, M. J.
Takahashi, M.
Brugal, G.
Christen, H.
Gahm, T.
Goodell, R. M.
Karakitsos, P.
Knesel, E. A.
Kobler, T.
Kyrkou, K. A.
Labbe, S.
Long, E. L.
Mango, L. J.
McGoogan, E.
Oberholzer, M.
Reith, A.
Winkler, C.
Publication Title: 
Journal of Vascular Surgery

Large databases can be a rich source of clinical and administrative information on broad populations. These datasets are characterized by demographic and clinical data for over 1000 patients from multiple institutions. Since they are often collected and funded for other purposes, their use for secondary analysis increases their utility at relatively low costs. Advantages of large databases as a source include the very large numbers of available patients and their related medical information. Disadvantages include lack of detailed clinical information and absence of causal descriptions.

Author(s): 
Nguyen, Louis L.
Barshes, Neal R.
Publication Title: 
Critical Care Medicine

OBJECTIVE: Because the results of a meta-analysis are used to formulate the highest level recommendation in clinical practice guidelines, clinicians should be mindful of problems inherent in this technique. Rather than reviewing meta-analysis in abstract, general terms, we believe readers can gain a more concrete understanding of the problems through a detailed examination of one meta-analysis.

Author(s): 
Tobin, Martin J.
Jubran, Amal
Publication Title: 
Journal of Chemical Information and Modeling

We report the development and implementation of a cheminformatics tool which aids in the design of compounds during exploratory chemistry and lead optimization. The Heterocyclic Regioisomer Enumeration and MDDR Search (HREMS) tool allows medicinal chemists to build greater structural diversity into their synthetic planning by enabling a systematic, automated enumeration of heterocyclic regioisomers of target structures.

Author(s): 
Tyagarajan, Sriram
Lowden, Christopher T.
Peng, Zhengwei
Dykstra, Kevin D.
Sherer, Edward C.
Krska, Shane W.

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