Zhurnal Vysshe? Nervno? Deiatelnosti Imeni I P Pavlova
The electrical activity of the right and left sensorimotor and premotor cortical areas and right and left medulary reticular formation was recorded during "animal hypnosis" in rabbits. In this state, the spectral power of potentials (predominantly, in the delta-range) recorded from the left reticular formation was higher than that recorded from the right side. The value of the function of coherence between the right and left reticular recordings was decreased to 0.1-0.2 in the whole frequency range.
BACKGROUND: Many general anesthetics are thought to produce a loss of wakefulness, in part, by enhancing gamma-aminobutyric acid (GABA) neurotransmission. However, GABAergic neurotransmission in the pontine reticular formation promotes wakefulness. This study tested the hypotheses that (1) relative to wakefulness, isoflurane decreases GABA levels in the pontine reticular formation; and (2) pontine reticular formation administration of drugs that increase or decrease GABA levels increases or decreases, respectively, isoflurane induction time.
Journal of Manipulative and Physiological Therapeutics
Pathways for visual (sensory) information into the CNS are explained. The hypothesized areas where this sensory information begins to initiate the motor program include the periarcuate area, superior colliculus, and the areas of the motor program such as the Cortex, superior colliculus and reticular formation, along with the control exerted on the systems via the cerebellum and vestibular nuclei. The information demonstrates that the co-ordinated movements of eye-head-neck towards a goal, involves a number of parallel independently active neural centres which initiate the movements.