Retinoblastoma

Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Plants are the valuable source of natural products with important medicinal properties. Most of the approved anti cancer drugs have a natural product origin or are natural products. Retinoblastoma is the most common ocular cancer of children. Although chemotherapy is the preferred mode of therapy, a successful treatment for retinoblastoma requires enucleation. Chebulagic acid (CA) from Terminalia chebula was shown to have anti-proliferative properties in the studies on cancerous cell lines.

Author(s): 
Kumar, Naresh
Gangappa, D.
Gupta, Geetika
Karnati, Roy
Publication Title: 
Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology

PURPOSE: This report proposes hypnosis as a valid alternative to general anaesthesia for immobilisation and set-up in certain cases in paediatric radiotherapy. METHODS: We report three cases of children who underwent radiotherapy in 1994 and were treated using hypnosis for set-up during irradiation.

Author(s): 
Bertoni, F.
Bonardi, A.
Magno, L.
Mandracchia, S.
Martinelli, L.
Terraneo, F.
Tonoli, S.
Publication Title: 
Cancer Biotherapy & Radiopharmaceuticals

Our previous studies have shown that high-mobility group box 1 (HMGB1) could physically associate with the retinoblastoma (RB) protein via an LXCXE (leucine-X-cysteine-X-glutamic; X=any amino acid) motif. An identical LXCXE motif is present in the HMGB1-3 protein sequences, whereas a near-consensus LXCXD (leucine-X-cysteine-X-asparagine; X=any amino acid) motif is found in the HMGB4 protein.

Author(s): 
Wang, Li-Li
Meng, Qing-Hui
Jiao, Yang
Xu, Jia-Ying
Ge, Chun-Min
Zhou, Ju-Ying
Rosen, Eliot M.
Wang, Hai-Chao
Fan, Sai-Jun
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