Rosaceae

Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

AIM: The aim of the present study was to investigate the usefulness of rose essential oil as a supplementary and adjunctive therapy for the relief of renal colic, specifically because rose essential oil is soothing and can act as a muscle relaxant. MATERIALS: Eighty patients who were diagnosed with renal colic in the emergency room were included in the study, with ages ranging from 19 to 64 years.

Author(s): 
Ayan, Murat
Tas, Ufuk
Sogut, Erkan
Suren, Mustafa
Gurbuzler, Levent
Koyuncu, Feridun
Publication Title: 
Journal of Agricultural and Food Chemistry

Four wild berry species, Amelanchier alnifolia, Viburnum trilobum, Prunus virginiana, and Shepherdia argentea, all integral to the traditional subsistence diet of Native American tribal communities, were evaluated to elucidate phytochemical composition and bioactive properties related to performance and human health. Biological activity was screened using a range of bioassays that assessed the potential for these little-known dietary berries to affect diabetic microvascular complications, hyperglycemia, pro-inflammatory gene expression, and metabolic syndrome symptoms.

Author(s): 
Burns Kraft, Tristan F.
Dey, Moul
Rogers, Randy B.
Ribnicky, David M.
Gipp, David M.
Cefalu, William T.
Raskin, Ilya
Lila, Mary Ann
Publication Title: 
Pharmaceutical Research

PURPOSE: Results from our oral cavity chemoprevention trial demonstrated appreciable interpatient variations regarding chemopreventive efficacy of a freeze dried black raspberry (FBR) gel. We speculated these data reflected individual patient-related differences in absorption, target tissue uptake and local compound metabolism of key FBR compounds (anthocyanins). Accordingly, this study assessed the distribution of anthocyanins from the 10% (w/w) FBR gel in saliva, oral tissues and plasma.

Author(s): 
Ugalde, Carlos M.
Liu, Zhongfa
Ren, Chen
Chan, Kenneth K.
Rodrigo, Kapila A.
Ling, Yhonghua
Larsen, Peter E.
Chacon, Guillermo E.
Stoner, Gary D.
Mumper, Russell J.
Fields, Henry W.
Mallery, Susan R.
Publication Title: 
Journal of Agricultural and Food Chemistry

The quality of botanical food is increasingly assessed by the content of multiple bioactive compounds. This study reports, for the first time, an HPLC fingerprinting method for the quality evaluation of Rubus suavissimus leaves possessing multiple bioactivities. Five constituents, gallic acid, rutin, ellagic acid, rubusoside, and steviol monoside, were quantified and used in developing qualitative chromatographic fingerprints. The limits of detection and quantification ranged from 0.29 to 37.86 mug/mL.

Author(s): 
Chou, Guixin
Xu, Shun-Jun
Liu, Dong
Koh, Gar Yee
Zhang, Jian
Liu, Zhijun
Publication Title: 
Journal of Agricultural and Food Chemistry

The aqueous extraction process of the leaves of Rubus suavissimus often brings in a large amount of nonactive polysaccharides as part of the constituents. To purify this water extract for potential elevated bioactivity, an alcohol precipitation (AP) consisting of gradient regimens was applied, and its resultants were examined through colorimetric and HPLC analyses. AP was effective in partitioning the aqueous crude extract into a soluble supernatant and an insoluble precipitant, and its effect varied significantly with alcohol regimens.

Author(s): 
Koh, Gar Yee
Chou, Guixin
Liu, Zhijun
Publication Title: 
Journal of Agricultural and Food Chemistry

Wild berries are integral dietary components for Alaska Native people and a rich source of polyphenolic metabolites that can ameliorate metabolic disorders such as obesity and diabetes. In this study, five species of wild Alaskan berries (Vaccinium ovalifolium , Vaccinium uliginosum , Rubus chamaemorus , Rubus spectabilis , and Empetrum nigrum) were screened for bioactivity through a community-participatory research method involving three geographically distinct tribal communities.

Author(s): 
Kellogg, Joshua
Wang, Jinzhi
Flint, Courtney
Ribnicky, David
Kuhn, Peter
De Mejia, Elvira González
Raskin, Ilya
Lila, Mary Ann
Publication Title: 
PloS One

BACKGROUND: Biofilms contribute to the pathogenesis of many forms of Staphylococcus aureus infection. Treatment of these infections is complicated by intrinsic resistance to conventional antibiotics, thus creating an urgent need for strategies that can be used for the prevention and treatment of biofilm-associated infections. METHODOLOGY/PRINCIPAL FINDINGS: This study demonstrates that a botanical natural product composition (220D-F2) rich in ellagic acid and its derivatives can limit S. aureus biofilm formation to a degree that can be correlated with increased antibiotic susceptibility.

Author(s): 
Quave, Cassandra L.
Estévez-Carmona, Miriam
Compadre, Cesar M.
Hobby, Gerren
Hendrickson, Howard
Beenken, Karen E.
Smeltzer, Mark S.
Publication Title: 
Biological & Pharmaceutical Bulletin

A 35% EtOH extract of the fruits of Chaenomeles sinensis, long utilized as a folk medicine for cough, significantly inhibited the pruritogenic agent compound 48/80 (COM)-induced scratching behavior in mice. Antipruritic activity-guided fractionation and purification yielded active quercetin, apigenin, and catechin derivatives, which exhibited significant inhibitory effects on COM-induced scratching behavior. To the best of our knowledge, apigenin (5), apigenin 7-glucronide (6), and apigenin 4'-methoxy-7-glucronide (acacetin 7-glucronide) (7) were isolated from the fruits of C.

Author(s): 
Oku, Hisae
Ueda, Yoshimi
Ishiguro, Kyoko
Publication Title: 
Biological & Pharmaceutical Bulletin

The Rubus species has been used in folk medicine to treat several ailments, including infectious and dolorous diseases. In this work we evaluate the phytochemical and analgesic activity of hydroalcoholic extract (HE), some fractions (hexane, dichloromethane, ethyl acetate and butanolic), as well as a pure compound denoted as 28-methoxytormentic acid (1) obtained from aerial parts of R. rosaefolius. The compounds were isolated and identified by chromatographic and spectroscopic analysis.

Author(s): 
Kanegusuku, Márcia
Sbors, Danúbia
Bastos, Eliza Stefanelo
de Souza, Márcia Maria de
Cechinel-Filho, Valdir
Yunes, Rosendo Augusto
Delle Monache, Franco
Niero, Rivaldo
Publication Title: 
Molecules (Basel, Switzerland)

The fruit of Chaenomeles speciosa is a traditional Chinese medicine used for the treatment of dyspepsia and various inflammatory diseases. In the present study, we evaluated the potential radical scavenging capacity, and activity against nitrous oxide, inflammatory cytokines production and neuramindase (NA) of its isolates.

Author(s): 
Zhang, Li
Cheng, Yong-Xian
Liu, Ai-Lin
Wang, Hai-Di
Wang, Ya-Ling
Du, Guan-hua

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