Saliva

Publication Title: 
Acupuncture in Medicine: Journal of the British Medical Acupuncture Society

BACKGROUND: Irradiation-induced xerostomia seriously reduces quality of life for patients with head and neck cancer (HNC). Anecdotal evidence suggests that acupuncture may be beneficial. OBJECTIVE: To systematically review evidence on clinical effectiveness and safety of acupuncture in irradiation-induced xerostomia in patients with HNC. METHODS: A detailed search was performed to identify randomised controlled trials (RCTs) and systematic reviews of RCTs on acupuncture in irradiation-induced xerostomia, using AMED, BNIA, CINAHL, Cochrane, Embase, HPSI, PsycInfo and Medline.

Author(s): 
O'Sullivan, E. M.
Higginson, I. J.
Publication Title: 
Oral Oncology

INTRODUCTION: Salivary gland hypofunction is a common and permanent adverse effect of radiotherapy to the head and neck. Randomised trials of available treatment modalities have produced unclear results and offer little reliable guidance for clinicians to inform evidence-based therapy. We have undertaken this systematic review and meta-analysis to estimate the effectiveness of available interventions for radiotherapy-induced xerostomia and hyposalivation.

Author(s): 
Mercadante, Valeria
Al Hamad, Arwa
Lodi, Giovanni
Porter, Stephen
Fedele, Stefano
Publication Title: 
Journal of Ethnopharmacology

The aqueous extract from Terminalia chebula was tested for its ability to inhibit the growth and some physiological functions of Streptococcus mutans. The extract strongly inhibited the growth, sucrose induced adherence and glucan induced aggregation of S. mutans. Mouthrinsing with a 10% solution of the extract inhibited the salivary bacterial count and salivary glycolysis.

Author(s): 
Jagtap, A. G.
Karkera, S. G.
Publication Title: 
Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research

Plant-derived medicines have been a part of our traditional health care system, and the antimicrobial properties of plant-derived compounds are well documented. The purpose of this study is to evaluate the effect of an aqueous extract of Terminalia chebula (a medicinal plant) on salivary samples and its potential for use as an anticaries agent in the form of mouthwash. A concentrated aqueous extract was prepared from the fruit of T. chebula . A mouth rinse of 10% concentration was prepared by diluting the extract in sterile distilled water.

Author(s): 
Carounanidy, Usha
Satyanarayanan, R.
Velmurugan, A.
Publication Title: 
Oral Health & Preventive Dentistry

PURPOSE: The aim of the present study was to assess the effectiveness of Terminalia chebula aqueous extract rinse on salivary pH and Streptococcus mutans. Mouthrinses have been in use from time immemorial as a supplement for routine oral hygiene practice. Although a large number of mouthrinses are currently available, many of them possess certain drawbacks, which has necessitated the search for alternate agents. MATERIALS AND METHODS: Ten per cent of T. chebula extract was prepared. A purposive sample of 30 subjects was selected and randomly divided into extract and control groups.

Author(s): 
Nayak, Sushma S.
Kumar, B. R. Ashok
Ankola, Anil V.
Hebbal, Mamata
Publication Title: 
The Ceylon Medical Journal

INTRODUCTION: Different systems of traditional medicine of the Indian subcontinent, have used Acacia chundra Willd, Adhatoda vasica Nees., Mimusops elengi L., Piper nigrum L., Pongamia pinnata L. Pirerre, Quercus infectoria Olivier., Syzygium aromaticum L., Terminalia chebula Retz., Zingiber officinale Roscoe., individually or in combinations, to cure oral diseases. OBJECTIVE: To investigate the oral hygiene and gingival health benefits of toothpaste formulated with a mixture of the above herbs (15% w/w).

Author(s): 
Jayashankar, S.
Panagoda, G. J.
Amaratunga, E. a. P. D.
Perera, K.
Rajapakse, P. S.
Publication Title: 
Journal of the Indian Society of Pedodontics and Preventive Dentistry

OBJECTIVES: Dental caries is the most prevalent oral disease. Streptococcus mutans plays a major role in the occurrence of dental caries. Many antibacterial agents have been developed against dental caries. However, they lack the qualities of an ideal agent. Thus presently, antibacterial activity of herbal agents is being extensively studied. MATERIALS AND METHODS: In the present study, ethanol extract of Terminalia chebula was prepared and mouthrinse was formulated.

Author(s): 
Nayak, S. S.
Ankola, A. V.
Metgud, S. C.
Bolmal, U.
Publication Title: 
Phytotherapy research: PTR

A double blind, randomized, controlled study with three parallel treatment groups was done to evaluate the efficacy of a Terminalia chebula 10% mouth rinse compared with chlorhexidine 0.12% mouth rinse, applied two times daily for 2 weeks, in the treatment of dental plaque and gingivitis. Seventy-eight patients were included in the study. The efficacy variables were periodontal indices on days 0, 7 and 14 after commencement of therapy. Twenty six patients received chlorhexidine mouth rinse, twenty six Terminalia chebula mouth rinse and twenty six received saline solution.

Author(s): 
Gupta, Devanand
Bhaskar, D. J.
Gupta, Rajendra Kumar
Karim, Bushra
Gupta, Vipul
Punia, Himanshu
Batra, Manu
Jain, Ankita
Agarwal, Amit
Singh, Pradeep
Publication Title: 
The Ceylon Medical Journal

INTRODUCTION: Plant derived preparations have been essential components for maintenance of oral hygiene and the treatment of oral diseases globally since ancient times. Acacia chundra Willd, Adhatoda vasica Nees., Mimusops elengi L., Piper nigrum L., Pongamia pinnate L. Pirerre, Quercus infectoria Olivier., Syzygium aromaticum L., Terminalia chebula Retz., Zingiber offici-nale Roscoe., individually or in combination, have been used for this purpose because of their beneficial effects.

Author(s): 
Howshigan, J.
Perera, K.
Samita, S.
Rajapakse, P. S.
Publication Title: 
Psychological Science

We compared how evaluations by out-group members and evaluations by in-group members affected participants' stress responses--their neuroendocrine reactivity, cognitive appraisals, and observed anxiety--and how participants' implicit racial bias moderated these responses. Specifically, White participants completed measures of racial bias prior to the experiment. During the experiment, participants performed speech and serial subtraction tasks in front of White or Black interviewers.

Author(s): 
Mendes, Wendy Berry
Gray, Heather M.
Mendoza-Denton, Rodolfo
Major, Brenda
Epel, Elissa S.

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