Wilson disease is a hereditary disorder caused by mutations of the ATP7B gene, which leads to intoxication with copper as a result of an unbalance of copper homeostasis. The clinical manifestations resulting from this intoxication are related to the affectation of liver and the encephalon in most cases. Several animal models are currently available for the study of the malady. However, in such models no neurological symptoms are observed, which limits their use for the study of pathogenic effects of this disease on the central nervous system.
A survey of the attitudes and practices of general practitioners in Northern Ireland regarding contraception and abortion was carried out in 1994 and 1995 with a randomized sample of 154 physicians. The vast majority of doctors who received requests for contraceptives from their patients fulfilled those request (94%). Overall, 13% of the doctors said a married patient had requested an abortion in the past three months, and 34% had had a similar request from an unmarried patient.
Physicians' religious attributes are unknown, and may affect patient care. The Women Physicians' Health Study (WPHS) is a random sample (n = 4501 respondents, 59% response rate) of US women physicians aged 30-70; the first large, national study of US women physicians. In this study US women physicians were less likely to be Christian than were other Americans (61.2% of women physicians versus 85.1% of the general population), but were more likely to be Jewish (13.2% vs 2.0%), Buddhist (1.4% vs 0.3%), Hindu (3.9% vs 0.4%), or atheist/agnostic (5.9% vs 0.6%).
Older, sedentary, urban-living, ethnic minority women are at high risk for preventable disease, but it is difficult to engage this population in health promotion efforts. This study tested two methods of engaging Hispanic and African American women, who were at high risk for cardiovascular disease, in a 10-week aerobic fitness program. The program was offered to 76 participants, in either a women's health clinic or a church. Attendance was the primary dependent variable and was recorded at each exercise session.
This is an exploratory study using qualitative methods to investigate and highlight psychosocial needs as perceived by individuals who have survived an attempted suicide through self-poisoning. Respondents consisted of a convenience sample of six people (three male and three female). Data were collected through interviews and analysed using the principles of content analysis devised by Field and Morse. Major needs identified include the need to be loved, the need to maintain a high level of self-esteem, the need to have control of one's life and the need to be supported.
The way in which sex may be constructed as safe through its relationship with 'love' is the concern of this study. Interviews with 112 heterosexual women and men from discos and bars in Melbourne, Australia, catering to single adults revealed the pervasive construction of sex within the discourses of 'love' and 'romance'. The relationship of these discourses to unsafe practices is discussed and the article presents an analysis of the normative function of the sex-as-love/sex-as-desire opposition in terms of safe sex and HIV/AIDS prevention.
AIDS education and prevention: official publication of the International Society for AIDS Education
Although there is some evidence that relationship-level factors influence sexual behavior, they have received far less attention than individual-level factors as potential correlates of condom use. This study surveyed 210 undergraduate men and women to examine the association between relationship characteristics and condom use. Higher levels of love, longer relationships and more serious and committed relationships were individually associated with less condom use.
The aim of this study was to test some of the main hypotheses derived from Buss' Sexual Strategies Theory on a representative Spanish sample. These hypotheses refer to the different strategies men and woman seem to adopt when they want to engage in a short-term sexual relationship (fling), or in a long-term one (loving relationship). (The technical term "strategies", unlike its equivalent in everyday language, is not meant to imply something necessarily planned or conscious). Data was obtained by self-report from a representative sample of 1949 Spanish people.
European Journal of Oncology Nursing: The Official Journal of European Oncology Nursing Society
BACKGROUND: Women with recurring ovarian cancer are living longer, due to advances in treatment options. They are now often outpatients, experiencing rapid encounters on treatment days. Whether this shift in care meets women's needs has been scarcely explored scientifically. PURPOSE OF THE STUDY: This study aimed to illuminate the phenomenon of living with recurring ovarian cancer as experienced by women in that condition. METHODS AND SAMPLE: A descriptive phenomenological method was used.
The study compared personal interviews and a postal survey, posing the same questions to two random samples independently drawn from the same population. It sought reasons why respondents began and may subsequently terminate, involvement as voluntary blood donors in Toronto Canada. The priorities of respondents (ordinal rankings) were virtually identical in the two samples, notwithstanding a clear response rate and socio-economic differential between the modes. Differences in item response rates were compatible with explanations involving interviewer bias and question threat.