Sea Bream

Publication Title: 
Molecular Immunology

Neutrophils are major cells participants in innate host responses. They are short-lived leukocytes, although microbial products activate intracellular signaling cascades that prolong their survival by inhibiting constitutive apoptosis. To gain insight into the phylogeny of this important cell type, we examined the ability of toll-like receptor agonists to extend the lifespan of gilthead seabream (Sparus aurata L.) acidophilic granulocytes, which are the functional equivalent of mammalian neutrophils.

Author(s): 
Sepulcre, MarÌa P.
LÛpez-MuÒoz, Azucena
Angosto, Diego
GarcÌa-Alcazar, Alicia
Meseguer, JosÈ
Mulero, Victoriano
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