Seizures

Publication Title: 
BMJ clinical evidence

INTRODUCTION: About 3% of people will be diagnosed with epilepsy during their lifetime, but about 70% of people with epilepsy eventually go into remission. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the benefits and risks of starting anti-epileptic drug treatment following a single seizure? What are the effects of monotherapy in newly diagnosed partial epilepsy, and in newly diagnosed generalised epilepsy (tonic clonic type)?

Author(s): 
Marson, Anthony G.
Maguire, Melissa
Ramaratnam, Sridharan
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: This is an updated version of the original Cochrane review published in The Cochrane Library, Issue 1, 2002.Yoga may induce relaxation and stress reduction, and influence the electroencephalogram and the autonomic nervous system, thereby controlling seizures. Yoga would be an attractive therapeutic option for epilepsy if proved effective.

Author(s): 
Panebianco, Mariangela
Sridharan, Kalpana
Ramaratnam, Sridharan
Publication Title: 
Seizure

PURPOSE: The aim of this meta-analysis is to evaluate and synthesize the available evidence from the previous 20 years regarding the utility of psychological interventions in the management of psychogenic non-epileptic seizures (PNES). METHOD: Studies were retrieved from MEDLINE via OvidSP and PsychINFO. Selection criteria included controlled and before-after non-controlled studies including case series, using seizure frequency as an outcome measurement. Studies were required to assess one or more types of psychological intervention for the treatment of PNES in adults.

Author(s): 
Carlson, Perri
Nicholson Perry, Kathryn
Publication Title: 
Epilepsy & Behavior: E&B

OBJECTIVE: The purpose of this Cochrane Review was to establish the evidence base for treatment of psychogenic nonepileptic seizures. METHODS: Six hundred eight references were identified using a search strategy designed with the support of the Cochrane Review Epilepsy Group library. The search employed Medline and PsychInfo, and included hand searches of relevant journals (Seizure, Epilepsia, Epilepsy &Behavior, Epilepsy Research). RESULTS: Three studies were found that met the inclusion criteria; two used hypnosis and one used paradoxical therapy.

Author(s): 
Brooks, Jayne L.
Goodfellow, Laura
Bodde, Nynke M. G.
Aldenkamp, Albert
Baker, Gus A.
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: Psychogenic non-epileptic seizures (NES) have the outward appearance of epilepsy in the absence of physiological or electroencephalographic correlates. Non-epileptic seizures can occur in isolation or in combination with epileptic seizures.

Author(s): 
Baker, G. A.
Brooks, J. L.
Goodfellow, L.
Bodde, N.
Aldenkamp, A.
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: Psychogenic non-epileptic seizures, also known as non-epileptic attack disorder (NEAD), have the outward appearance of epilepsy in the absence of physiological or electroencephalographic correlates. Non-epileptic seizures can occur in isolation or in combination with epileptic seizures.

Author(s): 
Martlew, Jayne
Pulman, Jennifer
Marson, Anthony G.
Publication Title: 
Journal of Pediatric Hematology/Oncology

Acupuncture has been used therapeutically in China for thousands of years and is growing in prominence in Europe and the United States. In a recent review of complementary and alternative medicine use in the US population, an estimated 2.1 million people or 1.1% of the population sought acupuncture care during the past 12 months. Four percent of the US population used acupuncture at any time in their lives. We reviewed 31 different published journal articles, including 23 randomized controlled clinical trials and 8 meta-analysis/systematic reviews.

Author(s): 
Jindal, Vanita
Ge, Adeline
Mansky, Patrick J.
Publication Title: 
The journal of ECT

Electroconvulsive therapy (ECT) is one of the most effective methods for managing treatment-resistant depression. Although the proposed mechanisms of action have thus far mainly been investigated at the cellular level, recent observations and developments in the field of molecular biology and genomics have provided novel insights in the actual molecular underpinnings of dynamic alterations in gene expression, particularly in response to environmental exposures, and experience-dependent plasticity, both of which are highly relevant to ECT.

Author(s): 
de Jong, Job O. Z.
Arts, Baer
Boks, Marco P.
Sienaert, Pascal
van den Hove, Daniel L. A.
Kenis, Gunter
van Os, Jim
Rutten, Bart P. F.
Publication Title: 
Neurobiology of Disease

Sexual differentiation of the developing brain organizes the neural architecture differently between males and females, and the main influence on this process is exposure to gonadal steroids during sensitive periods of prenatal and early postnatal development. Many molecular and cellular processes are influenced by steroid hormones in the developing brain, including gene expression, cell birth and death, neurite outgrowth and synaptogenesis, and synaptic activity.

Author(s): 
Kight, Katherine E.
McCarthy, Margaret M.
Publication Title: 
Medicina Nei Secoli

A short Italian text dating the end of XVIII century examines the problem of convulsions of women relating them to the ancient topic of love sickness. Ancient Greek and Roman medical and non medical literature, together with literary texts are used by the author Giovanni Pirani to draw the picture of a moral illness strictly related to a physical dimension.

Author(s): 
Gazzaniga, Valentina

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