Selenium Compounds

Publication Title: 
Bulletin Du Cancer

Use of complementary and alternative medicine (CAM) has been reported to be more and more frequent among cancer patients in USA. The aim of this study was to analyze among French cancer patients the prevalence of CAM use, focusing on antioxidants (AO) that could interfere with antitumor agents. Seventy-nine patients, treated by antitumor chemotherapy in oncology day care unit, participated to an interview (medium age ?= ?60 years old).

Author(s): 
Thomas-Schoemann, Audrey
Alexandre, Jérôme
Mongaret, Céline
Azibi, Sonia
Dauphin, Alain
Goldwasser, François
Lemare, Francois
Publication Title: 
The Medical Journal of Malaysia

Neem, Azadirachta indica, is a plant from the family Meliaceae, known as "Pokok Semambu" in Malay community. It has been extensively used in India as traditional Ayurvedic and folklore minedicine for the treatment of various diseases. This study aimed to determine the distribution of selenium in the liver of rats during hepatocarcinogenesis when neem aqueous extract and dietary selenium was supplemented.

Author(s): 
Hanachi, P.
Loh, L. N.
Fauziah, O.
Rafiuz, Z. H.
Tee, S. T.
Lye, C. W.
Lam, T. P.
Publication Title: 
Bioorganic & Medicinal Chemistry

Inhibition of intestinal α-glucosidases and pancreatic α-amylases is an approach to controlling blood glucose and serum insulin levels in individuals with Type II diabetes. The two human intestinal glucosidases are maltase-glucoamylase and sucrase-isomaltase. Each incorporates two family 31 glycoside hydrolases responsible for the final step of starch hydrolysis.

Author(s): 
Jones, Kyra
Sim, Lyann
Mohan, Sankar
Kumarasamy, Jayakanthan
Liu, Hui
Avery, Stephen
Naim, Hassan Y.
Quezada-Calvillo, Roberto
Nichols, Buford L.
Pinto, B. Mario
Rose, David R.
Publication Title: 
ACS nano

Semiconductor quantum dots (Qdots) are a promising new technology with benefits in the areas of medical diagnostics and therapeutics. Qdots generally consist of a semiconductor core, capping shell, and surface coating. The semiconductor core of Qdots is often composed of group II and VI metals (e.g., Cd, Se, Te, Hg) that are known to have toxic properties. Various surface coatings have been shown to stabilize Qdots and thus shield cells from the toxic properties of their core elements.

Author(s): 
Smith, Wesley E.
Brownell, Jessica
White, Collin C.
Afsharinejad, Zahra
Tsai, Jesse
Hu, Xiaoge
Polyak, Stephen J.
Gao, Xiaohu
Kavanagh, Terrance J.
Eaton, David L.
Publication Title: 
Bulletin Du Cancer

Use of complementary and alternative medicine (CAM) has been reported to be more and more frequent among cancer patients in USA. The aim of this study was to analyze among French cancer patients the prevalence of CAM use, focusing on antioxidants (AO) that could interfere with antitumor agents. Seventy-nine patients, treated by antitumor chemotherapy in oncology day care unit, participated to an interview (medium age  =  60 years old).

Author(s): 
Thomas-Schoemann, Audrey
Alexandre, Jérôme
Mongaret, Céline
Azibi, Sonia
Dauphin, Alain
Goldwasser, François
Lemare, Francois
Publication Title: 
Archives of Internal Medicine

BACKGROUND: Selenium is an element necessary for normal cellular function, but it can have toxic effects at high doses. We investigated an outbreak of acute selenium poisoning. METHODS: A case was defined as the onset of symptoms of selenium toxicity in a person within 2 weeks after ingesting a dietary supplement manufactured by "Company A," purchased after January 1, 2008. We conducted case finding, administered initial and 90-day follow-up questionnaires to affected persons, and obtained laboratory data where available.

Author(s): 
MacFarquhar, Jennifer K.
Broussard, Danielle L.
Melstrom, Paul
Hutchinson, Richard
Wolkin, Amy
Martin, Colleen
Burk, Raymond F.
Dunn, John R.
Green, Alice L.
Hammond, Roberta
Schaffner, William
Jones, Timothy F.
Publication Title: 
Archives of Internal Medicine

BACKGROUND: Selenium is an element necessary for normal cellular function, but it can have toxic effects at high doses. We investigated an outbreak of acute selenium poisoning. METHODS: A case was defined as the onset of symptoms of selenium toxicity in a person within 2 weeks after ingesting a dietary supplement manufactured by "Company A," purchased after January 1, 2008. We conducted case finding, administered initial and 90-day follow-up questionnaires to affected persons, and obtained laboratory data where available.

Author(s): 
MacFarquhar, Jennifer K.
Broussard, Danielle L.
Melstrom, Paul
Hutchinson, Richard
Wolkin, Amy
Martin, Colleen
Burk, Raymond F.
Dunn, John R.
Green, Alice L.
Hammond, Roberta
Schaffner, William
Jones, Timothy F.
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