Serenoa

Publication Title: 
The New England Journal of Medicine

BACKGROUND: Saw palmetto is used by over 2 million men in the United States for the treatment of benign prostatic hyperplasia and is commonly recommended as an alternative to drugs approved by the Food and Drug Administration. METHODS: In this double-blind trial, we randomly assigned 225 men over the age of 49 years who had moderate-to-severe symptoms of benign prostatic hyperplasia to one year of treatment with saw palmetto extract (160 mg twice a day) or placebo.

Author(s): 
Bent, Stephen
Kane, Christopher
Shinohara, Katsuto
Neuhaus, John
Hudes, Esther S.
Goldberg, Harley
Avins, Andrew L.
Publication Title: 
Complementary Therapies in Medicine

BACKGROUND: Saw palmetto is commonly used by men for lower-urinary tract symptoms. Despite its widespread use, very little is known about the potential toxicity of this dietary supplement. METHODS: The Saw palmetto for Treatment of Enlarged Prostates (STEP) study was a randomized clinical trial performed among 225 men with moderate-to-severe symptoms of benign prostatic hyperplasia, comparing a standardized extract of the saw palmetto berry (160 mg twice daily) with a placebo over a 1-year period.

Author(s): 
Avins, Andrew L.
Bent, Stephen
Staccone, Suzanne
Badua, Evelyn
Padula, Amy
Goldberg, Harley
Neuhaus, John
Hudes, Esther
Shinohara, Katusto
Kane, Christopher
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: Benign prostatic hyperplasia (BPH), a nonmalignant enlargement of the prostate, can lead to obstructive and irritative lower urinary tract symptoms (LUTS). The pharmacologic use of plants and herbs (phytotherapy) for the treatment of LUTS associated with BPH is common. The extract of the berry of the American saw palmetto, or dwarf palm plant, Serenoa repens (also known by its botanical name of Sabal serrulatum), is one of several phytotherapeutic agents available for the treatment of BPH.

Author(s): 
Tacklind, James
MacDonald, Roderick
Rutks, Indy
Wilt, Timothy J.
Publication Title: 
Planta Medica

Twenty-four herbal dietary supplement powder and extract reference standards provided by the National Institute of Standards and Technology (NIST) were investigated using three different commercially available DNA extraction kits to evaluate DNA availability for downstream nucleotide-based applications. The material included samples of Camellia, Citrus, Ephedra, Ginkgo, Hypericum, Serenoa, And Vaccinium. Protocols from Qiagen, MoBio, and Phytopure were used to isolate and purify DNA from the NIST standards. The resulting DNA concentration was quantified using SYBR Green fluorometry.

Author(s): 
Cimino, Matthew T.
Publication Title: 
Integrative Cancer Therapies

The use of dietary supplements for various ailments enjoys unprecedented popularity. As part of this trend, Sabal serrulata (saw palmetto) constitutes the complementary treatment of choice with regard to prostate health. In homeopathy, Sabal serrulata is commonly prescribed for prostate problems ranging from benign prostatic hyperplasia to prostate cancer.

Author(s): 
MacLaughlin, Brian W.
Gutsmuths, Babett
Pretner, Ewald
Jonas, Wayne B.
Ives, John
Kulawardane, Don Victor
Amri, Hakima
Publication Title: 
Planta Medica

Twenty-four herbal dietary supplement powder and extract reference standards provided by the National Institute of Standards and Technology (NIST) were investigated using three different commercially available DNA extraction kits to evaluate DNA availability for downstream nucleotide-based applications. The material included samples of Camellia, Citrus, Ephedra, Ginkgo, Hypericum, Serenoa, And Vaccinium. Protocols from Qiagen, MoBio, and Phytopure were used to isolate and purify DNA from the NIST standards. The resulting DNA concentration was quantified using SYBR Green fluorometry.

Author(s): 
Cimino, Matthew T.
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