Skin Transplantation

Publication Title: 
Canadian Medical Association Journal

Hypnosis was used to alter body image in an attempt to enable a woman to retain a skin homograft from an unrelated male donor. The man also acted as a nonhypnotized control by receiving a homograft from the hypnotized woman. Oneinch square full-thickness skin homografts were exchanged between the upper arms of the two volunteers. The homograft on the arm of the woman is still viable after eight months; the homograft on the man was rejected within two weeks.

Author(s): 
Fogel, S.
Knight, C. R.
Publication Title: 
The International Journal of Clinical and Experimental Hypnosis
Author(s): 
Wiggins, S. L.
Brown, C. W.
Publication Title: 
Laboratory Animal Care
Author(s): 
Gruber, R. P.
Amato, J. J.
Publication Title: 
British Journal of Plastic Surgery

The use of hypnotherapy to modify the reactions of 13 patients undergoing pedicle flap operations is described. The morale and mental approach of these patients was improved. Premedication and hypnotic drug requirements were reduced to nil following hypnotic training. Analgesic medication was also reduced, not being required at all following nearly two-thirds of the operations.

Author(s): 
Scott, D. L.
Publication Title: 
Anaesthesia
Author(s): 
Scott, D. L.
Publication Title: 
Burns: Journal of the International Society for Burn Injuries

BACKGROUND: Pain is a major issue after burns even when large doses of opioids are prescribed. The study focused on the impact of a pain protocol using hypnosis on pain intensity, anxiety, clinical course, and costs. METHODS: All patients admitted to the ICU, aged >18 years, with an ICU stay >24h, accepting to try hypnosis, and treated according to standardized pain protocol were included. Pain was scaled on the Visual Analog Scale (VAS) (mean of daily multiple recordings), and basal and procedural opioid doses were recorded.

Author(s): 
Berger, Mette M.
Davadant, Maryse
Marin, Christian
Wasserfallen, Jean-Blaise
Pinget, Christophe
Maravic, Philippe
Koch, Nathalie
Raffoul, Wassim
Chiolero, René L.
Publication Title: 
The Journal of Experimental Medicine

It is known that vitamin A and its metabolite, retinoic acid (RA), are essential for host defense. However, the mechanisms for how RA controls inflammation are incompletely understood. The findings presented in this study show that RA signaling occurs concurrent with the development of inflammation. In models of vaccination and allogeneic graft rejection, whole body imaging reveals that RA signaling is temporally and spatially restricted to the site of inflammation.

Author(s): 
Pino-Lagos, Karina
Guo, Yanxia
Brown, Chrysothemis
Alexander, Matthew P.
Elgueta, Raúl
Bennett, Kathryn A.
De Vries, Victor
Nowak, Elizabeth
Blomhoff, Rune
Sockanathan, Shanthini
Chandraratna, Roshantha A.
Dmitrovsky, Ethan
Noelle, Randolph J.
Publication Title: 
Immunity

Peripheral tolerance orchestrated by regulatory T cells, dendritic cells (DCs), and mast cells (MCs) has been studied in several models including skin allograft tolerance. We now define a role for MCs in controlling DC behavior ("conditioning") to facilitate tolerance. Under tolerant conditions, we show that MCs mediated a marked increase in tumor necrosis factor (TNFα)-dependent accumulation of graft-derived DCs in the dLN compared to nontolerant conditions.

Author(s): 
de Vries, Victor C.
Pino-Lagos, Karina
Nowak, Elizabeth C.
Bennett, Kathy A.
Oliva, Carla
Noelle, Randolph J.
Publication Title: 
Acta Chirurgiae Plasticae

The cosmetic and functional result in postburn scar deformities is influenced by following factors: 1. The type of patient's central nervous system and his response to burn injury. 2. Depth and site of burn areas. 3. Early excision and grafting. 4. Infection complications, their severity and location. 5. Fixation of dressings should be done using elastic materials and applied for so long until stabilisation of scars is completed. Elastic materials should be combined with rigid pressure and pressure massage. 6. Congenital predisposition of the patient to hypertrophic scarring.

Author(s): 
Bláha, J.
Pondĕlicek, I.
Publication Title: 
Journal of Burn Care & Research: Official Publication of the American Burn Association

The postoperative management of full-thickness burns of the neck can be a challenge for burn therapists despite the availability of many treatment modalities to minimize scar hypertrophy and contracture. Interventions include pressure appliances, massage, exercise, and positioning devices. The objective of this study was to identify factors associated with the development of neck contractures and optimal treatment strategies for their prevention.

Author(s): 
Sharp, Patricia A.
Dougherty, Mary E.
Kagan, Richard J.

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