Publication Title: 
Rheumatology (Oxford, England)

OBJECTIVE: To critically evaluate the evidence regarding complementary and alternative medicines (CAMs) taken orally or applied topically for the treatment of FM. METHODS: Randomized controlled trials of FM using CAMs, in comparison with other treatments or placebo, published in English up to March 2009, were eligible for inclusion. They were identified using systematic searches of bibliographic databases and manual searching of reference lists.

De Silva, Vijitha
El-Metwally, Ashraf
Ernst, Edzard
Lewith, George
Macfarlane, Gary J.
Arthritis Research Campaign working group on complementary and alternative medicines
Publication Title: 
Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MÈtabolisme

We examined the effects of diets based on a low isoflavone or a high isoflavone soy protein isolates in normal, growth-hormone receptor knockout and Ames dwarf, and Prop 1 (df) mice that are hypoinsulinemic, insulin-sensitive, and exceptionally long-lived, as well as in growth hormone transgenic mice that are hyperinsulinemic, insulin-resistant, dyslipidemic, and short-lived. Soybean diets tended to normalize plasma cholesterol levels in dwarf and transgenic mice, while low isoflavone diet reduced plasma triglycerides in most of the examined genotypes.

Bartke, A.
Peluso, M. R.
Moretz, N.
Wright, C.
Bonkowski, M.
Winters, T. A.
Shanahan, M. F.
Kopchick, J. J.
Banz, W. J.
Publication Title: 
PloS One

The "organic food" market is the fastest growing food sector, yet it is unclear whether organically raised food is nutritionally superior to conventionally grown food and whether consuming organic food bestows health benefits. In order to evaluate potential health benefits of organic foods, we used the well-characterized fruit fly Drosophila melanogaster as a model system. Fruit flies were raised on a diets consisting of extracts of either conventionally or organically raised produce (bananas, potatoes, raisins, soy beans).

Chhabra, Ria
Kolli, Santharam
Bauer, Johannes H.
Publication Title: 
The Journal of Membrane Biology

Soy isoflavone's (genistein and daidzein in particular) biological significance has been thoroughly studied for decades, so we started from the premise that refreshed investigation approach in this field should consider identification of their new molecular targets. In addition to recently described epigenetic aspects of polyphenole action, the cell membrane constituents-mediated effects of soy isoflavones are worthy of special attention.

Ajdûanovi?, Vladimir
Medigovi?, Ivana
éivanovi?, Jasmina
Moji?, Marija
Miloöevi?, Verica
Publication Title: 
BioFactors (Oxford, England)

Natural leaves and flowers containing numerous aroma chemicals are widely used in aromatherapy since ancient times. In addition to their pleasant smells, aroma chemicals might have some beneficial health effects. Aroma extracts, isolated from coffee beans, soybeans, and mung beans by steam distillation under mild conditions (55 degrees C and 85 mm Hg) were examined for their antioxidative activities. The inhibitory effect of these extracts toward hexanal/hexanoic acid conversion was measured in the testing solution over prolonged time periods.

Lee, K. G.
Mitchell, A.
Shibamoto, T.
Publication Title: 
Zentralblatt Für Gynäkologie

After a introduction concerning complementary medicine, naturopathy and phytotherapy a general view of soy isoflavones as phytoestrogens will be given. In german speaking countries the term and topic naturopathy has a tradition of 150 years regarding theoretical development and practical use among lay people and health professionals in European culture. In contrary the term complementary medicine has been used for approximately 15 years in englisch speaking countries as a kind of collective name for European and Non-European medical cultures and traditions.

Melzer, J.
Brignoli, R.
Saller, R.
Publication Title: 
The Journal of Nutrition

Soy intake reduces cholesterol levels. However, both the identity of the soy component or components that contribute to this reduction and the cellular mechanism producing this reduction are unknown. Soy consists of protein, lipids, fiber, and phytochemicals including isoflavones. We propose that the isoflavone component of soy mediates this effect, at least in part, by affecting cellular sterol homeostasis.

Mullen, Eimear
Brown, Rachel M.
Osborne, Timothy F.
Shay, Neil F.
Publication Title: 
American Journal of Physiology. Heart and Circulatory Physiology

The antiatherogenic effects of soy isoflavone consumption have been demonstrated in a variety of studies. However, the mechanisms involved remain poorly defined. Adhesion of monocytes to vascular endothelial cells is a key step within the inflammatory cascade that leads to atherogenesis. Many factors, including the physical forces associated with blood flow, regulate this process.

Chacko, Balu K.
Chandler, Robert T.
Mundhekar, Ameya
Khoo, Nicholas
Pruitt, Heather M.
Kucik, Dennis F.
Parks, Dale A.
Kevil, Christopher G.
Barnes, Stephen
Patel, Rakesh P.
Publication Title: 
BMC neuroscience

BACKGROUND: Epidemiological studies have associated estrogen replacement therapy with a lower risk of developing Alzheimer's disease, but a higher risk of developing breast cancer and certain cardiovascular disorders. The neuroprotective effect of estrogen prompted us to determine potential therapeutic impact of soy-derived estrogenic compounds. Transgenic C. elegans, that express human beta amyloid (Abeta), were fed with soy derived isoflavones genistein, daidzein and glycitein (100 microg/ml) and then examined for Abeta-induced paralysis and the levels of reactive oxygen species.

Gutierrez-Zepeda, Astrid
Santell, Ross
Wu, Zhixin
Brown, Marishka
Wu, Yanjue
Khan, Ikhlas
Link, Christopher D.
Zhao, Baolu
Luo, Yuan
Publication Title: 
Cancer Research

Soy isoflavones are promising dietary agents for prevention of breast cancer. Isoflavones bind estrogen receptors (ER) and may variably act as either estrogen agonists or antagonists depending on the estrogen environment. In this study, we used a postmenopausal primate model to evaluate interactive effects of dietary soy isoflavones and estrogen on risk markers for breast cancer.

Wood, Charles E.
Register, Thomas C.
Franke, Adrian A.
Anthony, Mary S.
Cline, J. Mark


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