Steroids

Publication Title: 
Journal of Neurology

Carpal tunnel syndrome (CTS) is a common disorder, for which various conservative treatment options are available. The objective of this study is to determine the efficacy of the various conservative treatment options for relieving the symptoms of CTS. Computer-aided searches of MEDLINE (1/1966 to 3/2000), EMBASE (1/1988 to 2/2000) and the Cochrane Controlled Trials Register (2000, issue 1) were conducted, together with reference checking.

Author(s): 
Gerritsen, Annette A. M.
de Krom, Marc C. T. F. M.
Struijs, Margaretha A.
Scholten, Rob J. P. M.
de Vet, Henrica C. W.
Bouter, Lex M.
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: Non-surgical treatment for carpal tunnel syndrome is frequently offered to those with mild to moderate symptoms. The effectiveness and duration of benefit from non-surgical treatment for carpal tunnel syndrome remain unknown. OBJECTIVES: To evaluate the effectiveness of non-surgical treatment (other than steroid injection) for carpal tunnel syndrome versus a placebo or other non-surgical, control interventions in improving clinical outcome.

Author(s): 
O'Connor, D.
Marshall, S.
Massy-Westropp, N.
Publication Title: 
Journal of Neurology

Carpal tunnel syndrome (CTS) is a common disorder, for which various conservative treatment options are available. The objective of this study is to determine the efficacy of the various conservative treatment options for relieving the symptoms of CTS. Computer-aided searches of MEDLINE (1/1966 to 3/2000), EMBASE (1/1988 to 2/2000) and the Cochrane Controlled Trials Register (2000, issue 1) were conducted, together with reference checking.

Author(s): 
Gerritsen, Annette A. M.
de Krom, Marc C. T. F. M.
Struijs, Margaretha A.
Scholten, Rob J. P. M.
de Vet, Henrica C. W.
Bouter, Lex M.
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: Non-surgical treatment for carpal tunnel syndrome is frequently offered to those with mild to moderate symptoms. The effectiveness and duration of benefit from non-surgical treatment for carpal tunnel syndrome remain unknown. OBJECTIVES: To evaluate the effectiveness of non-surgical treatment (other than steroid injection) for carpal tunnel syndrome versus a placebo or other non-surgical, control interventions in improving clinical outcome.

Author(s): 
O'Connor, D.
Marshall, S.
Massy-Westropp, N.
Publication Title: 
British Journal of Sports Medicine

BACKGROUND: A variety of therapeutic interventions is available for restoring motion and diminishing pain in patients with frozen shoulder. An overview article concerning the evidence for the effectiveness of these interventions is lacking. OBJECTIVE: To provide an evidence-based overview regarding the effectiveness of conservative and surgical interventions to treat the frozen shoulder. METHODS: The Cochrane Library, PubMed, Embase, Cinahl and Pedro were searched for relevant systematic reviews and randomised clinical trials (RCTs).

Author(s): 
Favejee, M. M.
Huisstede, B. M. A.
Koes, B. W.
Publication Title: 
Cancer Nursing

BACKGROUND: Transarterial chemoembolization (TACE) is an established treatment in managing liver primary neoplasms or liver metastases. Postembolization syndrome (PES) is a common adverse event defined as fever without associated sepsis, pain in the right upper quadrant, and nausea and/or vomiting. OBJECTIVE: This integrative review aims to identify effective management strategies for PES or one of its characterizing symptoms (fever, pain, and nausea and/or vomiting). METHODS: Searches of electronic databases MEDLINE, EMBASE, and CINAHL were conducted.

Author(s): 
Blackburn, Helen
West, Sandra
Publication Title: 
Molecular Psychiatry

Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor.

Author(s): 
Baron-Cohen, S.
Auyeung, B.
N¯rgaard-Pedersen, B.
Hougaard, D. M.
Abdallah, M. W.
Melgaard, L.
Cohen, A. S.
Chakrabarti, B.
Ruta, L.
Lombardo, M. V.
Publication Title: 
Medical Hypotheses

Music is well known for its effect on human behavior especially of their bonding and empathy towards others. Music provokes one's emotion and activates mirror neurons and reward system. It also regulates social hormones such as steroid hormones or peptides, and increases empathy, pro-sociality and altruism. As a result, it improves one's reproductive success.

Author(s): 
Fukui, Hajime
Toyoshima, Kumiko
Publication Title: 
The International Journal of Clinical and Experimental Hypnosis
Author(s): 
Maher-Loughnan, G. P.
Publication Title: 
Ciba Foundation Symposium

Certain endogenous steroids are modulators of GABAA receptors. Tetrahydroprogesterone (THP, 5 alpha-pregnan-3 alpha-ol-20-one) and tetrahydrodeoxy-corticosterone (THDOC, 5 alpha-pregnane-3 alpha, 21-diol-20-one) behave as allosteric agonists of GABAA receptors whereas pregnenolone sulphate acts as an antagonist. THP and THDOC modulate ligand binding to GABAA receptors like barbiturates; they potentiate binding of the GABAA receptor agonist muscimol and the benzodiazepine flunitrazepam and they allosterically inhibit binding of the convulsant t-butylbicyclophosphorothionate.

Author(s): 
Majewska, M. D.

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