Thermosensing

Publication Title: 
Cell

Both poikilotherms and homeotherms live longer at lower body temperatures, highlighting a general role of temperature reduction in lifespan extension. However, the underlying mechanisms remain unclear. One prominent model is that cold temperatures reduce the rate of chemical reactions, thereby slowing the rate of aging. This view suggests that cold-dependent lifespan extension is simply a passive thermodynamic process. Here, we challenge this view in C. elegans by showing that genetic programs actively promote longevity at cold temperatures.

Author(s): 
Xiao, Rui
Zhang, Bi
Dong, Yongming
Gong, Jianke
Xu, Tao
Liu, Jianfeng
Xu, X. Z. Shawn
Publication Title: 
Cancer Chemotherapy and Pharmacology

PURPOSE: Chemoneuropathy remains a painful, burdensome complication of cancer treatment for patients receiving a range of chemotherapeutics, yet the cause and persistence of this condition are not fully documented. This study was designed to quantify the longevity of and contributions to neuropathy following treatment with the plant alkaloids paclitaxel and vincristine.

Author(s): 
Boyette-Davis, Jessica A.
Cata, Juan P.
Driver, Larry C.
Novy, Diane M.
Bruel, Brian M.
Mooring, Deidre L.
Wendelschafer-Crabb, Gwen
Kennedy, William R.
Dougherty, Patrick M.
Publication Title: 
Zeitschrift Für Die Gesamte Experimentelle Medizin
Author(s): 
von EIFF, A. W.
Publication Title: 
Psychological Review
Author(s): 
Hilgard, E. R.
Publication Title: 
The Journal of Nervous and Mental Disease

A quantitative investigation of the EEG during hypnosis was made by analyzing the analogue power frequency spectrum of one group of subjects in the awake and hypnotized conditions, and another group (random sample) in the awake condition. Individuals of the first group were thoroughly experienced in self-hypnosis and highly hypnotizable, whereas those of the second group had never been hypnotized and were low in waking suggestibility.

Author(s): 
Teb?cis, A. K.
Provins, K. A.
Farnbach, R. W.
Pentony, P.
Publication Title: 
The International Journal of Clinical and Experimental Hypnosis

Pain reports and amplitudes of painful argon laser-induced brain potentials were obtained for 10 high and 10 low hypnotizable volunteers following placebo and a randomized sequence of four hypnotically induced conditions of (a) neutral hypnosis, (b) deep relaxation, (c) pleasant dissociated "out of body" imagery, and (d) focused analgesia of the hand. Both high and low hypnotizable subjects exhibited significant reductions of reported pain during conditions of neutral hypnosis, relaxation, dissociated imagery, and focused analgesia.

Author(s): 
Zachariae, R.
Bjerring, P.
Publication Title: 
Psychosomatic Medicine

OBJECTIVE: To investigate the cross-sectional associations among self-reported weekly strenuous exercise bouts, anxiety sensitivity, and their interaction with pain catastrophizing and pain responses to the cold pressor task (CPT) in healthy, ethnically diverse young adults (n = 79). Exercise involvement has been shown to have hypoalgesic effects and cognitive factors may partially explain this effect. Particularly, alterations in pain catastrophizing have been found to mediate the positive pain outcomes of multidisciplinary treatments incorporating exercise.

Author(s): 
Goodin, Burel R.
McGuire, Lynanne M.
Stapleton, Laura M.
Quinn, Noel B.
Fabian, Lacy A.
Haythornthwaite, Jennifer A.
Edwards, Robert R.
Publication Title: 
Zeitschrift Für Rheumatologie

Superficial heat and cold are commonly used therapeutic methods in patients with rheumatoid arthritis. Both procedures have analgesic effect. In 30 inpatients with rheumatoid arthritis the pain threshold was measured before and after warm bath and ice massage. Rheumatoid patients had significantly lower pain threshold compared to the healthy subjects in normal circumstances. Heat and cold remarkably raise the pain threshold right after the application. The pain threshold is also raised 10 and 30 min after cryotherapy, but not after the warm bath.

Author(s): 
Curković, B.
Vitulić, V.
Babić-Naglić, D.
Dürrigl, T.
Publication Title: 
Oral Diseases

OBJECTIVE: Keratocystic odontogenic tumors (KOTs) can be treated with Carnoy's solution, although this treatment modality is not free from complications. It is important to verify the incidence of complications after the use of Carnoy's solution and compare these with the literature. MATERIALS AND METHODS: This study verified the effects of a complementary treatment for KOTs and assessed the incidence of such complications as recurrence, infection, sequestrum formation, mandibular fracture, dehiscence, and neuropathy.

Author(s): 
Ribeiro Junior, O.
Borba, A. M.
Alves, C. a. F.
de Gouveia, M. M.
Coracin, F. L.
Guimarães Júnior, J.
Publication Title: 
Cancer Chemotherapy and Pharmacology

PURPOSE: Chemoneuropathy remains a painful, burdensome complication of cancer treatment for patients receiving a range of chemotherapeutics, yet the cause and persistence of this condition are not fully documented. This study was designed to quantify the longevity of and contributions to neuropathy following treatment with the plant alkaloids paclitaxel and vincristine.

Author(s): 
Boyette-Davis, Jessica A.
Cata, Juan P.
Driver, Larry C.
Novy, Diane M.
Bruel, Brian M.
Mooring, Deidre L.
Wendelschafer-Crabb, Gwen
Kennedy, William R.
Dougherty, Patrick M.

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