Thiobarbituric Acid Reactive Substances

Publication Title: 

Four aqueous extracts from different parts of medicinal plants used in Ayurveda (an ancient Indian Medicine) viz., Momardica charantia Linn (AP1), Glycyrrhiza glabra (AP2), Acacia catechu (AP3), and Terminalia chebula (AP4) were examined for their potential as antioxidants. The antioxidant activity of these extracts was tested by studying the inhibition of radiation induced lipid peroxidation in rat liver microsomes at different doses in the range of 100-600 Gy as estimated by thiobarbituric acid reactive substances (TBARS).

Naik, G. H.
Priyadarsini, K. I.
Satav, J. G.
Banavalikar, M. M.
Sohoni, D. P.
Biyani, M. K.
Mohan, H.
Publication Title: 
Medicinal Chemistry (Shariqah (United Arab Emirates))

Ethanolic extracts of 30 Thai medicinal plants, traditionally used as alternative treatments in diabetes, were evaluated for antioxidative activity by the 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) method. They were evaluated in vitro for oxidative stress by thiobarbituric acid-reactive substance (TBARS) assay in pooled plasma of diabetic patients compared to without treatment of the extracts (control). The extracts were also assayed for protein glycation. The results showed that five plants had strong antioxidant activity: Phyllanthus emblica Linn.

Kusirisin, W.
Srichairatanakool, S.
Lerttrakarnnon, P.
Lailerd, N.
Suttajit, M.
Jaikang, C.
Chaiyasut, C.
Publication Title: 
African journal of traditional, complementary, and alternative medicines: AJTCAM

BACKGROUND: The present study compares the protective properties of aqueous extracts of six medicinal plants, Phyllanthus emblica, Terminalia chebula (black and yellow), Terminalia arjuna, Balsamodendron Mukul and Alium sativum against lipid per-oxidation in mice brain. METHODS: The antioxidant activities were analyzed by lipid per-oxidation assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical assay, total antioxidant activity and metal chelation.

Khan, Asmatullah
Nazar, Halima
Sabir, Syed Mubashar
Irshad, Muhammad
Awan, Shahid Iqbal
Abbas, Rizwan
Akram, Muhammad
Khaliq, Abdul
Rocha, João Batista Texeira
Ahmad, Syed Dilnawaz
Malik, Farnaz
Publication Title: 
International Journal of Molecular Sciences

Essential oils extracted from aromatic plants exhibit important biological activities and have become increasingly important for the development of aromatherapy for complementary and alternative medicine. The essential oil extracted from Cinnamomum cassia Presl (CC-EO) has various functional properties; however, little information is available regarding its anti-tyrosinase and anti-melanogenic activities. In this study, 16 compounds in the CC-EO have been identified; the major components of this oil are cis-2-methoxycinnamic acid (43.06%) and cinnamaldehyde (42.37%).

Chou, Su-Tze
Chang, Wen-Lun
Chang, Chen-Tien
Hsu, Shih-Lan
Lin, Yu-Che
Shih, Ying
Publication Title: 
Indian Journal of Physiology and Pharmacology

Oxidative stress contributes to the process of aging as well as a variety of chronic degenerative diseases. There are indications that psychological stress increases oxidative stress whereas relaxation decreases it. We have measured the concentration of thiobarbituric acid reactive substances (TBARS) in blood as an indicator of oxidative stress at the beginning and at the end of a comprehensive yoga-based lifestyle modification program (YLMP). The data was collected from 104 subjects (59 male, 45 female), 19-71 years of age (mean +/- SD, 41.2 +/- 14.6 years).

Yadav, Raj Kumar
Ray, Rooma Basu
Vempati, Ramaprabhu
Bijlani, Ramesh Lal
Publication Title: 
Asia Pacific Journal of Clinical Nutrition

The antioxidant effect of an aqueous extract of Phaseolus vulgaris pods, an indigenous plant used in Ayurvedic medicine in India, was studied in rats with streptozotocin-induced diabetes. Oral administration of Phaseolus vulgaris pod extract (PPEt; 200 mg/kg body weight) for 45 days resulted in a significant reduction in thiobarbituric acid reactive substances and hydroperoxides.

Venkateswaran, Subramanian
Pari, Leelavinothan
Publication Title: 
International Journal of Experimental Diabetes Research

Diabetes mellitus has been treated orally with herbal remedies based on folk medicine since ancient times. Embelia ribes burm (Myrsinaceae), known commonly as vidanga, was used in Ayurveda for its anthelmintic activity. Ayurveda describes vidanga as pungent, causes increase in digestive fire, and cures flatulence and colic. A single study reported the antihyperglycemic activity of decoction of E. ribes in glucose-induced hyperglycemic albino rabbits. In the present study, the lipid-lowering and antioxidant potential of ethanolic extract of E.

Bhandari, Uma
Kanojia, Raman
Pillai, K. K.
Publication Title: 
PloS One

BACKGROUND AND AIMS: Free radicals are implicated in the aetiology of some gastrointestinal disorders such as gastric ulcer, colorectal cancer and inflammatory bowel disease. In the present study we investigated the antioxidant and genoprotective activity of some rotenoids (i.e. boeravinones) isolated from the roots of Boerhaavia diffusa, a plant used in the Ayurvedic medicine for the treatment of diseases affecting the gastrointestinal tract.

Aviello, Gabriella
Canadanovic-Brunet, Jasna M.
Milic, Natasa
Capasso, Raffaele
Fattorusso, Ernesto
Taglialatela-Scafati, Orazio
Fasolino, Ines
Izzo, Angelo A.
Borrelli, Francesca
Publication Title: 
Liver International: Official Journal of the International Association for the Study of the Liver

BACKGROUND: Cholestasis is a common disease of the liver. Chronic cholestasis eventually leads to hepatic cirrhosis and fibrosis, and rodent chronic cholestasis models are used to study aspects of fibrosis and cirrhosis. Cholestasis-induced liver injury and fibrosis are associated with increased oxidative stress and inflammation. Few pharmacological therapies exist for treatment of cholestasis or cirrhosis, but it is known that humans with better nutritional intake are less likely to develop certain types of cirrhosis.

Donepudi, Ajay C.
Aleksunes, Lauren M.
Driscoll, Maureen V.
Seeram, Navindra P.
Slitt, Angela L.
Publication Title: 
Biological & Pharmaceutical Bulletin

In India, Azadirachta indica is typically known as 'neem tree' and its leaves has long been used in the ayurvedic medical tradition as a treatment for diabetes mellitus. In-depth chromatographic investigation on chloroform extract resulted in identification of one new tetranortriterpenoid. Structural elucidation was established on the basis of spectral data as 24,25,26,27-tetranor-apotirucalla-(apoeupha)-1α-senecioyloxy-3α,7α-dihydroxy-14,20,22-trien-21,23-epoxy named by us as meliacinolin (1).

Perez-Gutierrez, Rosa Martha
Damian-Guzman, Monica


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