Thyroid Neoplasms

Publication Title: 
Cancer

BACKGROUND: Among patients with well differentiated papillary thyroid carcinoma who generally have an excellent prognosis and a near-normal lifespan, there exist subsets of patients who have significant risk for morbidity and mortality from this disease. It is important to define the patterns of disease progression and the clinical outcome of such patients to develop effective surveillance and treatment strategies.

Author(s): 
Vassilopoulou-Sellin, R.
Schultz, P. N.
Haynie, T. P.
Publication Title: 
Journal of Clinical Anesthesia

STUDY OBJECTIVE: To investigate whether the type of anesthetic agent administered affects the antitussive effect of remifentanil. DESIGN: Prospective randomized study. SETTING: Operating room of a university hospital. PATIENTS: 78 ASA physical status 1 and 2 women, aged 20 to 65 years, who were scheduled to undergo a thyroidectomy. INTERVENTIONS: Patients were randomly assigned to three groups to receive anesthesia with propofol (Group P), sevoflurane (Group S), or desflurane (Group D). The main anesthetics were titrated to maintain a target Bispectral Index for hypnosis of 40 to 60.

Author(s): 
Lee, Jae Hoon
Choi, Seung Ho
Choi, Yong Seon
Lee, Bahn
Yang, Shi Joon
Lee, Jeong-Rim
Publication Title: 
Thyroid: Official Journal of the American Thyroid Association

BACKGROUND: To report on the incidence and predictors of use of complementary and alternative medicine (CAM) among patients with thyroid cancer. METHODS: Data were collected using a web-based online anonymous survey under Institutional Review Board approval from Boston University. This report is based on 1327 responses from subjects with thyroid cancer. Patient factors were compared by univariate and multivariate analyses. RESULTS: After excluding multivitamin and prayer use, 74% (n=941) used CAM. Respondents were primarily over age 40, white, and female and held a college degree.

Author(s): 
Rosen, Jennifer E.
Gardiner, Paula
Saper, Robert B.
Filippelli, Amanda C.
White, Laura F.
Pearce, Elizabeth N.
Gupta-Lawrence, Rebecca L.
Lee, Stephanie L.
Publication Title: 
Thyroid: Official Journal of the American Thyroid Association

BACKGROUND: To report on the incidence and predictors of use of complementary and alternative medicine (CAM) among patients with thyroid cancer. METHODS: Data were collected using a web-based online anonymous survey under Institutional Review Board approval from Boston University. This report is based on 1327 responses from subjects with thyroid cancer. Patient factors were compared by univariate and multivariate analyses. RESULTS: After excluding multivitamin and prayer use, 74% (n=941) used CAM. Respondents were primarily over age 40, white, and female and held a college degree.

Author(s): 
Rosen, Jennifer E.
Gardiner, Paula
Saper, Robert B.
Filippelli, Amanda C.
White, Laura F.
Pearce, Elizabeth N.
Gupta-Lawrence, Rebecca L.
Lee, Stephanie L.
Publication Title: 
Endocrine

To report on the incidence and use of kelp among patients with thyroid cancer. Data were collected using a web-based online anonymous survey under Institutional Review Board approval from Boston University. This report is based on 27 responses from subjects with thyroid cancer who use kelp. Demographic factors and complementary and alternative use were included. Respondents were primarily over age 40, white, female and have at least a high school education. The top five modalities were multivitamins, special diets, herbal supplements, prayer for health reasons and herbal tea.

Author(s): 
Rosen, Jennifer E.
Gardiner, Paula
Saper, Robert B.
Pearce, Elizabeth N.
Hammer, Kallista
Gupta-Lawrence, Rebecca L.
Lee, Stephanie L.
Publication Title: 
Thyroid: Official Journal of the American Thyroid Association

BACKGROUND: To report on the incidence and predictors of use of complementary and alternative medicine (CAM) among patients with thyroid cancer. METHODS: Data were collected using a web-based online anonymous survey under Institutional Review Board approval from Boston University. This report is based on 1327 responses from subjects with thyroid cancer. Patient factors were compared by univariate and multivariate analyses. RESULTS: After excluding multivitamin and prayer use, 74% (n=941) used CAM. Respondents were primarily over age 40, white, and female and held a college degree.

Author(s): 
Rosen, Jennifer E.
Gardiner, Paula
Saper, Robert B.
Filippelli, Amanda C.
White, Laura F.
Pearce, Elizabeth N.
Gupta-Lawrence, Rebecca L.
Lee, Stephanie L.
Publication Title: 
Thyroid: Official Journal of the American Thyroid Association

BACKGROUND: Salivary dysfunction is the most common side effect associated with (131)I therapy in patients with differentiated thyroid cancer. The purpose of this study was to evaluate the effect of parotid gland (PG) massage on radioisotope accumulation in the salivary gland. METHODS: Sixty patients were included in this study. Using Tc-99m pertechnetate, two salivary scans were performed in all patients. In 30 patients, PG massage was performed between the two salivary gland scans, whereas in the other 30 patients no massage was performed between the two scans.

Author(s): 
Kim, Hae Won
Ahn, Byeong-Cheol
Lee, Sang-Woo
Lee, Jaetae
Publication Title: 
Thyroid: Official Journal of the American Thyroid Association

BACKGROUND: To report on the incidence and predictors of use of complementary and alternative medicine (CAM) among patients with thyroid cancer. METHODS: Data were collected using a web-based online anonymous survey under Institutional Review Board approval from Boston University. This report is based on 1327 responses from subjects with thyroid cancer. Patient factors were compared by univariate and multivariate analyses. RESULTS: After excluding multivitamin and prayer use, 74% (n=941) used CAM. Respondents were primarily over age 40, white, and female and held a college degree.

Author(s): 
Rosen, Jennifer E.
Gardiner, Paula
Saper, Robert B.
Filippelli, Amanda C.
White, Laura F.
Pearce, Elizabeth N.
Gupta-Lawrence, Rebecca L.
Lee, Stephanie L.
Publication Title: 
Thyroid: Official Journal of the American Thyroid Association

BACKGROUND: The incidence of thyroid cancer is four to five times higher in women than in men, suggesting a role for estrogen (E₂) in the pathogenesis of thyroid proliferative disease (TPD) that comprises cancer and goiter. The objective of this study was to investigate the antiestrogenic activity of 3,3'-diindolylmethane (DIM), a bioactive compound derived from cruciferous vegetables, in patients with TPD. METHODS: In this limited phase I clinical trial study, patients found to have TPD were administered 300 mg of DIM per day for 14 days.

Author(s): 
Rajoria, Shilpi
Suriano, Robert
Parmar, Perminder Singh
Wilson, Yushan Lisa
Megwalu, Uchechukwu
Moscatello, Augustine
Bradlow, H. Leon
Sepkovic, Daniel W.
Geliebter, Jan
Schantz, Stimson P.
Tiwari, Raj K.
Publication Title: 
PloS One

BACKGROUND: Thyroid cancer is the most common endocrine related cancer with increasing incidences during the past five years. Current treatments for thyroid cancer, such as surgery or radioactive iodine therapy, often require patients to be on lifelong thyroid hormone replacement therapy and given the significant recurrence rates of thyroid cancer, new preventive modalities are needed.

Author(s): 
Rajoria, Shilpi
Suriano, Robert
George, Andrea
Shanmugam, Arulkumaran
Schantz, Stimson P.
Geliebter, Jan
Tiwari, Raj K.

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