ETHNOPHARMACOLOGICAL RELEVANCE: Herbal and herbo-mineral preparations are being traditionally used in Indian medicines. The herbo-mineral preparations have several benefits that have been instrumental in their widespread use in treatment of different disorders by traditional medicinal practitioners. These include better stability, lower dosage, ease of storability and sustained availability.
The increasing prevalence of environmental pollution, especially soil contamination with heavy metals has led to their uptake in the human food chains through plant parts. Accumulation and magnification of heavy metals in human tissues through consumption of herbal remedies can cause hazardous impacts on health.
Since ancient times, herbs have been used as natural remedies for curing many physiological disorders. Traditional medicinal literature appreciated their value as nature's gift to mankind for the healing of illnesses. Some of the herbs have also been used for culinary purposes, and few of them have been used in cheese manufacture both as coagulating agents and flavor ingredients. Scientific investigations regarding biological activity and toxicity of chemical moieties present in many herbs have been carried out over a period of time.
The galls of Terminala chebula (Gaertn.) Retz. (Combretaceae) are used for the treatment of various diseases in folk medicine and has been found to posses anti-inflammatory, anti-bacterial, anti-helmintic, anti-tyrosinase, and anti-aging activities. Considering the ethano-botanical and diverse pharmacological applications of galls of T. chebula, in this study, we investigate the possible toxic effects of different gall extracts of T. chebula by Brine shrimp (Artemia salina) toxicity assay. The cytotoxicity test of leaf gall extracts (petroleum ether, chloroform, ethanol, and aqueous) of T.