Transplantation, Homologous

Publication Title: 
Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Author(s): 
Iqbal, Munir
Hodge, William
Publication Title: 
Birth Defects Original Article Series
Author(s): 
Makinodan, T.
Publication Title: 
Clinical Orthopaedics and Related Research

Methods for procurement, processing and distribution of allograft tissues have changed rapidly and many of the advances have resulted in widespread use of allograft tissues for reconstruction. However, unlike other types of orthopaedic implants, these human graft tissues are not simple commodities delivered to the surgeon or operating room in prepackaged sterile containers, but rather are more akin to gifts from a donor to a patient in need.

Author(s): 
Nicholas, Richard
Publication Title: 
American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons

The organ donor shortage has been the most important hindrance in getting listed patients transplanted. Living kidney donors who are incompatible with their intended recipients are an untapped resource for expanding the donor pool through participation in transplant exchanges. Chain transplantation takes this concept further, with the potential to benefit even more recipients.

Author(s): 
Butt, F. K.
Gritsch, H. A.
Schulam, P.
Danovitch, G. M.
Wilkinson, A.
Del Pizzo, J.
Kapur, S.
Serur, D.
Katznelson, S.
Busque, S.
Melcher, M. L.
McGuire, S.
Charlton, M.
Hil, G.
Veale, J. L.
Publication Title: 
Canadian Medical Association Journal

Hypnosis was used to alter body image in an attempt to enable a woman to retain a skin homograft from an unrelated male donor. The man also acted as a nonhypnotized control by receiving a homograft from the hypnotized woman. Oneinch square full-thickness skin homografts were exchanged between the upper arms of the two volunteers. The homograft on the arm of the woman is still viable after eight months; the homograft on the man was rejected within two weeks.

Author(s): 
Fogel, S.
Knight, C. R.
Publication Title: 
Journal of Experimental Therapeutics & Oncology

Dipterocarpaceous plants contain various resveratrol oligomers that exhibit a variety of biological activities, such as antibacterial and antitumor effects. Previously, we found that vaticanol C, a resveratrol tetramer, exhibits strong cytotoxicity against various tumor cell lines. In the present study, we examined the antitumor activity of the ethanol extract from the stem bark of Vateria indica, which has been traditionally used for health and healing diseases as Ayurveda in India.

Author(s): 
Mishima, Satoshi
Matsumoto, Kenji
Futamura, Yoshihiro
Araki, Yoko
Ito, Tetsuro
Tanaka, Toshiyuki
Iinuma, Munekazu
Nozawa, Yoshinori
Akao, Yukihiro
Publication Title: 
The Journal of Pharmacology and Experimental Therapeutics

Allogeneic hematopoietic cell transplantation (HCT) is widely used to treat patients with life-threatening malignant and nonmalignant hematological diseases. However, allogeneic HCT often is accompanied by severe and lethal complications from graft-versus-host disease (GVHD), in which activated donor T cells recognize histocompatibility antigenic mismatches and cause significant toxicity in the recipient. In the current study, we tested the hypothesis that activation of cannabinoid receptors on donor-derived T cells may prevent GVHD.

Author(s): 
Pandey, Rupal
Hegde, Venkatesh L.
Nagarkatti, Mitzi
Nagarkatti, Prakash S.
Publication Title: 
The Journal of Experimental Medicine

It is known that vitamin A and its metabolite, retinoic acid (RA), are essential for host defense. However, the mechanisms for how RA controls inflammation are incompletely understood. The findings presented in this study show that RA signaling occurs concurrent with the development of inflammation. In models of vaccination and allogeneic graft rejection, whole body imaging reveals that RA signaling is temporally and spatially restricted to the site of inflammation.

Author(s): 
Pino-Lagos, Karina
Guo, Yanxia
Brown, Chrysothemis
Alexander, Matthew P.
Elgueta, Raúl
Bennett, Kathryn A.
De Vries, Victor
Nowak, Elizabeth
Blomhoff, Rune
Sockanathan, Shanthini
Chandraratna, Roshantha A.
Dmitrovsky, Ethan
Noelle, Randolph J.
Publication Title: 
Vestnik Khirurgii Imeni I. I. Grekova

An experience with functional and physical and physical therapy employed postoperatively in 525 patients with injuries of 752 digital flexor tendons is reported. A primary suture on flexor tendons after the V.I. Rozov technic within the boundaries of the synovial-aponeurotic sheath was put on 252 fingers in 183 patients. Homoplasty of digital flexor tendons was performed in 342 patients (500 fingers), terms of the injury being from 2 months to 15 years.

Author(s): 
Kornilov, N. V.
Gol'dblat, V. I.
Iur'ev, P. V.
Publication Title: 
Vestnik Khirurgii Imeni I. I. Grekova

178 patients with various ligamental injuries were treated according to the technique elaborated at the Institute. To restore ligaments preserved tendon homografts from the long fibular tendon with a remained terminal bone fragment were employed. The techniques of Gay-Growth-Smith and Sitenko underlie the methods of tendinoplasty applied. Following the operation therapeutic exercises, using water basin, massage, mechanotherapy and different kinds of physical therapy were employed differentially. Good results were obtained in a vast majority of patients (91.6%).

Author(s): 
Eretskaia, M. F.
Zhukov, P. P.
Bulatova, O. N.
Roskov, R. V.
Iur'ev, P. V.

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