Urolithiasis

Publication Title: 
International Braz J Urol: Official Journal of the Brazilian Society of Urology

PURPOSE: Recurrence and persistent side effects of present day treatment for urolithiasis restrict their use, so an alternate solution, using phytotherapy is being sought. The present study attempted to evaluate the antilithiatic properties of Tribulus terrestris commonly called as "gokhru" which is often used in ayurveda to treat various urinary diseases including urolithiasis.

Author(s): 
Aggarwal, A.
Tandon, S.
Singla, S. K.
Tandon, C.
Publication Title: 
Fitoterapia

Several Ayurvedic plants are known to have activity against diverse urinary crystals. The traditional knowledge of Ayurveda, collective clinical experience in arthritis and the earlier experimental studies on urinary crystals led to the selection of three plants, viz. Rotula aquatica, Commiphora wightii Bhandari syn. C.mukul. and Boerhaavia diffusa for screening anticrystal activity against basic calcium phosphate (BCP), calcium pyrophosphate (CPPD) and monosodium urate monohydrate (MSUM). The effects of each plant were assayed on microcrystals in 24-well microplates in vitro.

Author(s): 
Raut, Ashwinikumar A.
Sunder, Sudha
Sarkar, Subrata
Pandita, Nancy S.
Vaidya, Ashok D. B.
Publication Title: 
Urological Research

Most of the drugs administered to stone patients appear to be inappropriate and doing more harm than good to the patients. The objective of this paper is to identify the prevalence of blind chemotherapy among the stone patients and find out the real indication for the drugs administered. Patients who attended the stone clinic for the first time were interviewed to find out what drugs they had been taking before the attendance at the stone clinic. 350 patients consuming specific drugs relevant to stone formation at least for a period of 15 days were selected for a detailed assessment.

Author(s): 
Fazil Marickar, Y. M.
Salim, Abiya
Vijay, Adarsh
Publication Title: 
International Braz J Urol: Official Journal of the Brazilian Society of Urology

PURPOSE: Recurrence and persistent side effects of present day treatment for urolithiasis restrict their use, so an alternate solution, using phytotherapy is being sought. The present study attempted to evaluate the antilithiatic properties of Tribulus terrestris commonly called as "gokhru" which is often used in ayurveda to treat various urinary diseases including urolithiasis.

Author(s): 
Aggarwal, A.
Tandon, S.
Singla, S. K.
Tandon, C.
Publication Title: 
Chinese Journal of Natural Medicines

INTRODUCTION: Cystone is an approved Ayurvedic polyherbal proprietary medicine used in India for various urinary disorders, including urolithiasis. AIM: To evaluate the protective effect of Cystone against hyperoxaluria-induced oxidative stress and calcium oxalate crystal deposition in urolithiasis. METHODS: Ethylene glycol (EG) (0.75%, V/V) in drinking water was given to rats for 28 days to induce urolithiasis with simultaneous treatment of Cystone (500 and 750 mg/kg body weight), and various urinary risk factors of urolithiasis and antioxidant markers were assessed.

Author(s): 
Bodakhe, Kiran S.
Namdeo, Kamta P.
Patra, Kartik C.
Machwal, Lalit
Pareta, Surendra K.
Publication Title: 
Indian Journal of Experimental Biology

Role of herbal drugs and medicinal plant extracts in the successful treatment of urolithiasis, classified as the third most common urinary tract diseases is well documented. Ayurvedic plants and their components mediate antilithogenic effects by altering ionic composition of urine, being diuretic, antioxidant or having antimicrobial activity. Therapeutic peptides and proteins have unique place in pharmaceutical biotechnology due to their critical roles in cell biology.

Author(s): 
Aggarwal, A.
Singla, S. K.
Tandon, C.
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