Vascular Resistance

Publication Title: 
The Journal of Clinical Investigation

Children conceived by assisted reproductive technologies (ART) display a level of vascular dysfunction similar to that seen in children of mothers with preeclamspia. The long-term consequences of ART-associated vascular disorders are unknown and difficult to investigate in healthy children. Here, we found that vasculature from mice generated by ART display endothelial dysfunction and increased stiffness, which translated into arterial hypertension in vivo. Progeny of male ART mice also exhibited vascular dysfunction, suggesting underlying epigenetic modifications.

Rexhaj, Emrush
Paoloni-Giacobino, Ariane
Rimoldi, Stefano F.
Fuster, Daniel G.
Anderegg, Manuel
Somm, Emmanuel
Bouillet, Elisa
Allemann, Yves
Sartori, Claudio
Scherrer, Urs
Publication Title: 
British Medical Journal
Maiolo, A. T.
Porro, G. B.
Granone, F.
Publication Title: 
Journal of Dental Research
Clark, R. E.
Forgione, A. G.
Publication Title: 
The American Journal of Clinical Hypnosis

Forearm arterial flow was measured in 22 healthy first-time blood donors during a 300-ml. blood letting and during the subsequent recovery. Blood pressure (BP) was also taken simultaneously and forearm peripheral resistance calculated. Following a transient BP and flow increase due to tachycardia related to needle insertion, both systolic BP and flow progressively and significantly decreased, while resistance increased. In a further 22 sex- and aged-matched highly hypnotizable subjects, blood donation was simulated by means of verbal hypnotic suggestions.

Casiglia, E.
Mazza, A.
Ginocchio, G.
Onesto, C.
Pessina, A. C.
Rossi, A.
Cavatton, G.
Marotti, A.
Publication Title: 
Journal of Clinical Anesthesia

STUDY OBJECTIVE: The objective of this study was to examine the utility of the transesophageal echo-Doppler device in evaluating hemodynamic changes during laparoscopic cholecystectomy. DESIGN: This was a prospective, controlled, observational open study. SETTING: The study took place in a university hospital. PATIENTS: Twenty patients with ASA physical statuses II and III undergoing laparoscopic cholecystectomy were enrolled into the study. INTERVENTIONS AND MEASUREMENTS: A standardized general anesthetic and surgical technique was used for all patients.

Joshi, Girish P.
Hein, H. A. Tillmann
Mascarenhas, Winston L.
Ramsay, Michael A. E.
Bayer, Ole
Klotz, Patricia
Publication Title: 
Zeitschrift Für Geburtshilfe Und Neonatologie

BACKGROUND: The aim of this study was to determine whether there are any changes in short time variation (STV), foetal movements, and blood flow in the umbilical artery in the trance state. METHODS: Six pregnant patients who had already attended two hypnoreflexogenous birth preparation course units had a standardised hypnosis intervention under cardiotocography (CTG). Using the CTG-Player ((R)) STVs and foetal movements were calculated from the electronically saved CTG traces and evaluated against control CTGs recorded before and after hypnosis.

Reinhard, J.
Hüsken-Janssen, H.
Hatzmann, H.
Schiermeier, S.
Publication Title: 
The International Journal of Clinical and Experimental Hypnosis

The authors detail their multidisciplinary collaboration of cardiologists, physiologists, neurologists, psychologists, engineers, and statisticians in researching the effects of hypnosis on the cardiovascular system and their additions to that incomplete literature. The article details their results and provides guidelines for researchers interested in replicating their research on hypnosis' effect on the cardiovascular system.

Casiglia, Edoardo
Tikhonoff, Valérie
Giordano, Nunzia
Andreatta, Elisa
Regaldo, Giuseppe
Tosello, Maria T.
Rossi, Augusto M.
Bordin, Daniele
Giacomello, Margherita
Facco, Enrico
Publication Title: 
The American Journal of Cardiology

This study reports the physiologic effects of up to 14 months of aerobic exercise in 101 older (greater than 60 years) men and women. After an extensive baseline physiologic assessment (Time 1), in which aerobic capacity and blood lipids were measured, subjects were randomized to an aerobic exercise condition (cycle ergometry, 3 times per week for 1 hour), nonaerobic yoga (2 times per week for 1 hour), or a waiting list nonexercise control group for 4 months, and then underwent a second (Time 2) assessment.

Blumenthal, J. A.
Emery, C. F.
Madden, D. J.
Coleman, R. E.
Riddle, M. W.
Schniebolk, S.
Cobb, F. R.
Sullivan, M. J.
Higginbotham, M. B.
Publication Title: 
Journal of Immunology (Baltimore, Md.: 1950)

The pathogenesis of sepsis is mediated in part by bacterial endotoxin, which stimulates macrophages/monocytes to sequentially release early (e.g., TNF, IL-1, and IFN-gamma) and late (e.g., high mobility group box 1 (HMGB1) protein) proinflammatory cytokines. The recent discovery of HMGB1 as a late mediator of lethal sepsis has prompted investigation for development of new experimental therapeutics.

Li, Wei
Li, Jianhua
Ashok, Mala
Wu, Rongqian
Chen, Dazhi
Yang, Lihong
Yang, Huan
Tracey, Kevin J.
Wang, Ping
Sama, Andrew E.
Wang, Haichao
Publication Title: 
Journal of Hypertension

OBJECTIVE: Input impedance is the frequency-dependent afterload to pulsatile blood flow. Studies of input impedance have been performed as early as the 1960s and have been applied to hypertension (HTN). However, to date, these studies have not been systematically evaluated. This systematic review aims to summarize the literature, interpret existing data from the perspective of impedance theory, and to discuss their potential for generating physiological insights into HTN.

Li, Weihui
Ahn, Andrew C.


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