Vitamin D

Publication Title: 
Evidence Report/Technology Assessment

BACKGROUND: Since the 1997 Dietary Reference Intake (DRI) values for vitamin D and calcium were established new data have become available on their relationship, both individually and combined, to a wide range of health outcomes. The Institute of Medicine/Food and Nutrition Board has constituted a DRI committee to undertake a review of the evidence and potential revision of the current DRI values for these nutrients.

Chung, Mei
Balk, Ethan M.
Brendel, Michael
Ip, Stanley
Lau, Joseph
Lee, Jounghee
Lichtenstein, Alice
Patel, Kamal
Raman, Gowri
Tatsioni, Athina
Terasawa, Teruhiko
Trikalinos, Thomas A.
Publication Title: 
Environmental Health Perspectives

BACKGROUND: Blood lead levels (BLLs) have been shown to increase during periods of high bone turnover such as pregnancy and menopause. OBJECTIVES: We examined the associations between bone turnover and micronutrient intake with BLLs in women 20-85 years of age (n = 2,671) participating in the National Health and Nutrition Examination Survey, 1999-2002. METHODS: Serum bone-specific alkaline phosphatase (BAP) and urinary cross-linked N-telopeptides (NTx) were measured as markers of bone formation and resorption, respectively. Lead was quantified in whole blood.

Jackson, Leila W.
Cromer, Barbara A.
Panneerselvamm, Ashok
Publication Title: 

The role of calcium in the prevention of bone loss in later life has been well established but little data exist on the adequacy of calcium intakes in elderly Australian women. The aim of this study was to compare the dietary intake including calcium of elderly Australian women with the Australian dietary recommendation, and to investigate the prevalence of calcium supplement use in this population. Community-dwelling women aged 70-80 years were randomly recruited using the Electoral Roll for a 2-year protein intervention study in Western Australia.

Meng, Xingqiong
Kerr, Deborah A.
Zhu, Kun
Devine, Amanda
Solah, Vicky
Binns, Colin W.
Prince, Richard L.
Publication Title: 
The American Journal of Clinical Nutrition

BACKGROUND: The Women's Health Initiative (WHI) randomized clinical trial (RCT) of calcium plus vitamin D (CaD) supplements found a 17% excess in urinary tract stone incidence in the supplemented group. This study evaluated whether this risk is modified by participant characteristics. OBJECTIVE: We examined the correlates of urinary tract stone occurrence in the CaD arm of the WHI trial.

Wallace, Robert B.
Wactawski-Wende, Jean
O'Sullivan, Mary Jo
Larson, Joseph C.
Cochrane, Barbara
Gass, Margery
Masaki, Kamal
Publication Title: 
The American Journal of Clinical Nutrition

BACKGROUND: The 2011 Dietary Reference Intakes (DRIs) for vitamin D use 25-hydroxyvitamin D [25(OH)D] concentrations to define vitamin D deficiency (<30 nmol/L), the Estimated Average Requirement (40 nmol/L), and the Recommended Dietary Allowance (RDA; 50 nmol/L). The Canadian population has not yet been assessed according to these recommendations. OBJECTIVE: We determined the prevalence of meeting DRI recommendations and the role of vitamin D supplement use among Canadians aged 6-79 y.

Whiting, Susan J.
Langlois, Kellie A.
Vatanparast, Hassanali
Greene-Finestone, Linda S.
Publication Title: 
Journal of the American Geriatrics Society

OBJECTIVES: To determine the prevalence and correlates of vitamin D insufficiency in black and white older adults. DESIGN: Cross-sectional. SETTING: Health, Aging and Body Composition Study. PARTICIPANTS: Nine hundred seventy-seven black and 1,604 white adults aged 70 to 81. MEASUREMENTS: Logistic regression and classification and regression tree analysis were used to identify correlates of vitamin D insufficiency (25-hydroxyvitamin D (25(OH)D) <30 ng/mL) separately in blacks and whites. RESULTS: The prevalence of 25(OH)D insufficiency was 84% in blacks and 57% in whites.

Shea, M. Kyla
Houston, Denise K.
Tooze, Janet A.
Davis, Cralen C.
Johnson, Mary Ann
Hausman, Dorothy B.
Cauley, Jane A.
Bauer, Douglas C.
Tylavsky, Frances
Harris, Tamara B.
Kritchevsky, Stephen B.
Health, Aging and Body Composition Study
Publication Title: 
The Journal of Nutrition

Vitamin D deficiency has recently been implicated as a possible risk factor in the etiology of numerous diseases, including nonskeletal conditions. In humans, skin synthesis following exposure to UVB is a potent source of vitamin D, but in regions with low UVB, individuals are at risk of vitamin D deficiency. Our objectives were to describe the prevalence of vitamin D deficiency and to investigate determinants of plasma 25-hydroxyvitamin D (25-OHD) concentrations in a high northern latitude country.

Zgaga, Lina
Theodoratou, Evropi
Farrington, Susan M.
Agakov, Felix
Tenesa, Albert
Walker, Marion
Knox, Susan
Wallace, A. Michael
Cetnarskyj, Roseanne
McNeill, Geraldine
Kyle, Janet
Porteous, Mary E.
Dunlop, Malcolm G.
Campbell, Harry
Publication Title: 
The Journal of Nutrition

Statistical modeling of habitual micronutrient intake from food and dietary supplements using short-term measurements is hampered by heterogeneous variances and multimodality. Summing short-term intakes from food and dietary supplements prior to simple correction for within-person variation (first add then shrink) may produce estimates of habitual total micronutrient intake so badly biased as to be smaller than estimates of habitual intake from food sources only.

Verkaik-Kloosterman, Janneke
Dodd, Kevin W.
Dekkers, Arnold L. M.
van 't Veer, Pieter
Ocké, Marga C.
Publication Title: 
Nutrition Journal

BACKGROUND: Seafood intake is associated with beneficial effects for human health. Seafood provides a number of nutrients beyond the traditionally known long chain marine n-3 fatty acids EPA, DPA and DHA, such as protein, vitamin D, iodine, selenium and vitamin B12. Valid assessment of dietary seafood and n-3 supplement intakes are becoming increasingly crucial when giving recommendations to populations as seafood consumption is regarded as an important part of a healthy and balanced diet.

Dahl, Lisbeth
Mæland, Camilla A.
Bjørkkjær, Tormod
Publication Title: 
Breast Cancer Research and Treatment

No studies of dietary vitamin D intake and vitamin D receptor (VDR) have been conducted comparing breast risk among Hispanic women and non-Hispanic white (NHW) women. We investigated the association between vitamin D intake and breast cancer in a population-based case-control study of 1,527 NHW and 791 Hispanic breast cancer cases diagnosed in 1999-2004 in Arizona, New Mexico, Utah, and Colorado, and 1,599 NHW and 922 Hispanic age-matched controls.

Rollison, Dana E.
Cole, Ashley L.
Tung, Ko-Hui
Slattery, Martha L.
Baumgartner, Kathy B.
Byers, Tim
Wolff, Roger K.
Giuliano, Anna R.


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