Wounds and Injuries

Publication Title: 
American Journal of Epidemiology

As yoga has gained popularity as a therapeutic intervention, its safety has been questioned in the lay press. Thus, this review aimed to systematically assess and meta-analyze the frequency of adverse events in randomized controlled trials of yoga. MEDLINE/PubMed, Scopus, the Cochrane Library, and IndMED were screened through February 2014. Of 301 identified randomized controlled trials of yoga, 94 (1975-2014; total of 8,430 participants) reported on adverse events.

Cramer, Holger
Ward, Lesley
Saper, Robert
Fishbein, Daniel
Dobos, Gustav
Lauche, Romy
Publication Title: 
Current Opinion in Supportive and Palliative Care

PURPOSE OF REVIEW: Pain is a significant concern in people with chronic wounds. A systematized approach is recommended for the management of wound-associated pain with the objectives to address pain relief, increase function, and restore overall quality of life. RECENT FINDINGS: Combinations of pharmacological agents are often recommended based on varying degree of pain severity, coexisting nociceptive and neuropathic pain, and chronic inflammation related to wound-associated pain.

Woo, Kevin Y.
Abbott, Laura K.
Librach, Lawrence
Publication Title: 
Ostomy/Wound Management

The use of natural medicine by both the general population and the nursing profession is increasing. Also referred to as unconventional, alternative, and complementary, these therapies often are derived from natural sources and facilitate improvements in health and well being by supporting innate healing processes of the body.

Leach, Matthew J.
Publication Title: 
Archives of Surgery (Chicago, Ill.: 1960)

BACKGROUND: The efficacy of homeopathic remedies has remained controversial. The homeopathic remedy most frequently studied in placebo-controlled clinical trials is Arnica montana. OBJECTIVE: To systematically review the clinical efficacy of homeopathic arnica. MATERIALS AND METHODS: Computerized literature searches were performed to retrieve all placebo-controlled studies on the subject. The following databases were searched: MEDLINE, EMBASE, CISCOM, and the Cochrane Library. Data were extracted in a predefined, standardized fashion independently by both authors.

Ernst, E.
Pittler, M. H.
Publication Title: 

Acupuncture is commonly used for pain control, but doubts about its effectiveness and safety remain. This review was aimed at critically evaluating systematic reviews of acupuncture as a treatment of pain and at summarizing reports of serious adverse effects published since 2000. Literature searches were carried out in 11 databases without language restrictions. Systematic reviews were considered for the evaluation of effectiveness and case series or case reports for summarizing adverse events. Data were extracted according to predefined criteria.

Ernst, E.
Lee, Myeong Soo
Choi, Tae-Young
Publication Title: 
Journal of Trauma Nursing: The Official Journal of the Society of Trauma Nurses

Challenges with opioids (e.g., adverse events, misuse and abuse with long-term administration) have led to a renewed emphasis on opioid-sparing multimodal management of trauma pain. To assess the extent to which currently available evidence supports the efficacy and safety of various nonopioid analgesics and techniques to manage trauma pain, a literature search of recently published references was performed. Additional citations were included on the basis of authors' knowledge of the literature.

Sullivan, Denise
Lyons, Mary
Montgomery, Robert
Quinlan-Colwell, Ann
Publication Title: 
Drug Research

Wound is defined as the loss of breaking cellular and functional continuity of the living tissues. Management of wounds is frequently encountered with different problems. Drug resistance and toxicity hindered the development of synthetic antimicrobial agents with wound healing activity. Many plants with potent pharmacological activities may offer better treatment options viz.

Khan, A. A.
Kumar, V.
Singh, B. K.
Singh, R.
Publication Title: 

Borderline personality is a well known concept in psychiatric literature, however, not fully understood as to its very nature. This article presents a short review of hypothesized etiologies of the borderline personality, starting with so called traditional theories, namely, borderline personality as a consolidated personality organization, in which the patient pathologically deals with his or her inner aggression, or with an enduring developmental failure.

Gil, Tsvi E.
Publication Title: 
Proceedings of the National Academy of Sciences of the United States of America

Childhood maltreatment is likely to influence fundamental biological processes and engrave long-lasting epigenetic marks, leading to adverse health outcomes in adulthood. We aimed to elucidate the impact of different early environment on disease-related genome-wide gene expression and DNA methylation in peripheral blood cells in patients with posttraumatic stress disorder (PTSD).

Mehta, Divya
Klengel, Torsten
Conneely, Karen N.
Smith, Alicia K.
Altmann, AndrÈ
Pace, Thaddeus W.
Rex-Haffner, Monika
Loeschner, Anne
Gonik, Mariya
Mercer, Kristina B.
Bradley, Bekh
M¸ller-Myhsok, Bertram
Ressler, Kerry J.
Binder, Elisabeth B.
Publication Title: 
Der Nervenarzt

BACKGROUND: Psychological trauma is considered to be a risk factor for the development of a number of psychiatric disorders. Although 40-90% of the population is exposed to a traumatic event in their lifetime, only a small fraction of individuals will develop a disorder. In recent years, numerous studies described epigenetic changes, such as DNA methylation, histone modifications and non-coding RNA as potential biological mechanisms by which the environment can have long-term effects on an organism.

Pape, J. C.
Binder, E. B.


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