Clinical Protocols

Publication Title: 
Systematic Reviews

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders of children and adolescents, with a significant impact on health services and the community in terms of economic and social burdens. The objective of this systematic review will be to evaluate the comparative efficacy and safety of pharmacological and non-pharmacological treatments in children and adolescents with ADHD.

Author(s): 
Catalá-López, Ferrán
Hutton, Brian
Núñez-Beltrán, Amparo
Mayhew, Alain D.
Page, Matthew J.
Ridao, Manuel
Tobías, Aurelio
Catalá, Miguel A.
Tabarés-Seisdedos, Rafael
Moher, David
Publication Title: 
Complementary Therapies in Clinical Practice

A systematic review revealed three small randomised controlled trials of yoga for low back pain, all of which showed effects on back pain that favoured the yoga group. To build on these studies a larger trial, with longer term follow-up, and a number of different yoga teachers delivering the intervention is required. This study protocol describes the details of a randomised controlled trial (RCT) to determine the effectiveness and cost-effectiveness of Yoga for chronic Low Back Pain, which is funded by Arthritis Research Campaign (arc) and is being conducted by the University of York.

Author(s): 
Cox, Helen
Tilbrook, Helen
Aplin, John
Chuang, Ling-Hsiang
Hewitt, Catherine
Jayakody, Shalmini
Semlyen, Anna
Soares, Marta O.
Torgerson, David
Trewhela, Alison
Watt, Ian
Worthy, Gill
Publication Title: 
Systematic Reviews

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders of children and adolescents, with a significant impact on health services and the community in terms of economic and social burdens. The objective of this systematic review will be to evaluate the comparative efficacy and safety of pharmacological and non-pharmacological treatments in children and adolescents with ADHD.

Author(s): 
Catalá-López, Ferrán
Hutton, Brian
Núñez-Beltrán, Amparo
Mayhew, Alain D.
Page, Matthew J.
Ridao, Manuel
Tobías, Aurelio
Catalá, Miguel A.
Tabarés-Seisdedos, Rafael
Moher, David
Publication Title: 
Journal of Clinical Nursing

AIMS AND OBJECTIVES: This study sought to assess the impact of a standardized protocol to maintain nasoenteral tube (NET) patency in patients requiring fluid restriction and identify factors associated with tube patency. BACKGROUND: Nasoenteral tube obstruction may interrupt nutritional support and prohibit drug administration. Balancing NET patency in the context of fluid restriction can be a challenge. DESIGN AND METHODS: The impact of the standardized protocol was assessed by using a quasi-experimental design and an historical control.

Author(s): 
Matsuba, Claudia St
De Gutiérrez, Maria Gr
Whitaker, Iveth Y.
Publication Title: 
Nursing Research

BACKGROUND: Behavior change is integral to the prevention and treatment of many disorders associated with deleterious lifestyles. Rigorous scientific testing of behavior change interventions is an important goal for nursing research. APPROACH: The stage model for behavioral therapy development is recommended as a useful framework for evaluating behavior change strategies. The NIH model specifies three stages from initial testing of novel behavioral therapies to their dissemination in community settings.

Author(s): 
Marcus, Marianne T.
Liehr, Patricia R.
Schmitz, Joy
Moeller, F. Gerald
Swank, Paul
Fine, Micki
Cron, Stanley
Granmayeh, L. Kian
Carroll, Deidra D.
Publication Title: 
BMJ open

INTRODUCTION: Chronic non-cancer pain (CNCP) affects up to 50% of the world's population. It impacts negatively on quality of life; entailing high costs on our medical systems, and translates to economic burden due to work loss. Aetiology of CNCP is complex and multifactorial, embracing the somatosensory, cognitive and affective domains. Opioid analgesia and other invasive interventions are often inadequate for clinical management of CNCP. Recently, mindfulness-based stress reduction (MBSR) has become a popular therapy for various medical conditions, including CNCP.

Author(s): 
Leung, Lawrence
Han, Han
Martin, Mary
Kotecha, Jyoti
Publication Title: 
AACN clinical issues

Patients with severe traumatic brain injury resulting in increased intracranial pressure refractory to first-tier interventions challenge the critical care team. After exhausting these initial interventions, critical care practitioners may utilize barbiturate-induced coma in an attempt to reduce the intracranial pressure. Titrating appropriate levels of barbiturate is imperative. Underdosing the drug may fail to control the intracranial pressure, whereas overdosing may lead to untoward effects such as hypotension and cardiac compromise.

Author(s): 
Bader, Mary Kay
Arbour, Richard
Palmer, Sylvain
Publication Title: 
The Journal of the American Board of Family Practice

BACKGROUND: Sexual problems are common but infrequently diagnosed. They are classified into four major categories: (1) sexual desire disorders, (2) sexual arousal disorders, (3) orgasmic disorders, and (4) sexual pain disorders. METHODS: MEDLINE files from 1966 to the present were searched using the specific sexual dysfunctions as key words along with the general key word "sexual dysfunction" to review the published literature. Additional articles came from the reference lists of dysfunction-specific reviews.

Author(s): 
Halvorsen, J. G.
Metz, M. E.
Publication Title: 
Lancet (London, England)

We tested, under independent conditions, the reproducibility of evidence from two previous trials that homoeopathy differs from placebo. The test model was again homoeopathic immunotherapy. 28 patients with allergic asthma, most of them sensitive to house-dust mite, were randomly allocated to receive either oral homoeopathic immunotherapy to their principal allergen or identical placebo. The test treatments were given as a complement to their unaltered conventional care. A daily visual analogue scale of overall symptom intensity was the outcome measure.

Author(s): 
Reilly, D.
Taylor, M. A.
Beattie, N. G.
Campbell, J. H.
McSharry, C.
Aitchison, T. C.
Carter, R.
Stevenson, R. D.
Publication Title: 
Systematic Reviews

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders of children and adolescents, with a significant impact on health services and the community in terms of economic and social burdens. The objective of this systematic review will be to evaluate the comparative efficacy and safety of pharmacological and non-pharmacological treatments in children and adolescents with ADHD.

Author(s): 
Catalá-López, Ferrán
Hutton, Brian
Núñez-Beltrán, Amparo
Mayhew, Alain D.
Page, Matthew J.
Ridao, Manuel
Tobías, Aurelio
Catalá, Miguel A.
Tabarés-Seisdedos, Rafael
Moher, David

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