Sleep

Publication Title: 
Nihon Rinsho. Japanese Journal of Clinical Medicine
Author(s): 
Osawa, S.
Publication Title: 
Journal of Women's Health (2002)
Author(s): 
Fossel, Michael
Walker, Richard
Publication Title: 
European Journal of Public Health

BACKGROUND: The aim of the present work was to evaluate various socio-demographic, clinical, lifestyle and psychological characteristics of elderly (> 65 years) and very elderly (> 90 years) individuals without known cardiovascular disease. METHODS: During 2005-7, 1190 elderly (aged > 65) men and women (from Cyprus, Mitilini, Samothraki, Cephalonia, Crete, Lemnos, Corfu and Zakynthos) were randomly enrolled. Socio-demographic, clinical, psychological and lifestyle factors were assessed using standard questionnaires and procedures.

Author(s): 
Tourlouki, Eleni
Polychronopoulos, Evangelos
Zeimbekis, Akis
Tsakountakis, Nikos
Bountziouka, Vassiliki
Lioliou, Eirini
Papavenetiou, Eftichia
Polystipioti, Anna
Metallinos, George
Tyrovolas, Stefanos
Gotsis, Efthimios
Matalas, Antonia-Leda
Lionis, Christos
Panagiotakos, Demosthenes B.
Publication Title: 
PLoS genetics

Organisms perceive changes in their dietary environment and enact a suite of behavioral and metabolic adaptations that can impact motivational behavior, disease resistance, and longevity. However, the precise nature and mechanism of these dietary responses is not known. We have uncovered a novel link between dietary factors and sleep behavior in Drosophila melanogaster.

Author(s): 
Linford, Nancy J.
Chan, Tammy P.
Pletcher, Scott D.
Publication Title: 
Gerontology

Across phyla, aging is associated with reduced sleep duration and efficiency. Both aging and sleep involve complex genetic architecture and diverse cell types and are heavily influenced by diet and environment. Therefore, understanding the molecular mechanisms of age-dependent changes in sleep will require integrative approaches that go beyond examining these two processes independently. The fruit fly, Drosophila melanogaster, provides a genetically amenable system for dissecting the molecular basis of these processes.

Author(s): 
Robertson, Meagan
Keene, Alex C.
Publication Title: 
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

Target of rapamycin inhibition by rapamycin feeding has previously been shown to extend life in genetically heterogeneous mice. To examine whether it similarly affected mouse health, we fed encapsulated rapamycin or a control diet to C57BL/6Nia mice of both sexes starting at 19 months of age. We performed a range of health assessments 6 and 12 months later. Rapamycin feeding significantly reduced mTOR activity in most but not all tissues.

Author(s): 
Zhang, Yiqiang
Bokov, Alex
Gelfond, John
Soto, Vanessa
Ikeno, Yuji
Hubbard, Gene
Diaz, Vivian
Sloane, Lauren
Maslin, Keith
Treaster, Stephen
RÈndon, Samantha
Van Remmen, Holly
Ward, Walter
Javors, Martin
Richardson, Arlan
Austad, Steven N.
Fischer, Kathleen
Publication Title: 
Brain, Behavior, and Immunity

Major depressive disorder (MDD) has been associated with reduced leukocyte telomere length (LTL). It is not known, however, whether psychosocial and behavioral protective factors moderate this association. In the current study, we examine whether multisystem resiliency--defined by healthy emotion regulation, strong social connections, and health behaviors (sleep and exercise)--predicts LTL and mitigates previously demonstrated associations between depression diagnosis and LTL.

Author(s): 
Puterman, Eli
Epel, Elissa S.
Lin, Jue
Blackburn, Elizabeth H.
Gross, James J.
Whooley, Mary A.
Cohen, Beth E.
Publication Title: 
Brain, Behavior, and Immunity

Major depressive disorder (MDD) has been associated with reduced leukocyte telomere length (LTL). It is not known, however, whether psychosocial and behavioral protective factors moderate this association. In the current study, we examine whether multisystem resiliency--defined by healthy emotion regulation, strong social connections, and health behaviors (sleep and exercise)--predicts LTL and mitigates previously demonstrated associations between depression diagnosis and LTL.

Author(s): 
Puterman, Eli
Epel, Elissa S.
Lin, Jue
Blackburn, Elizabeth H.
Gross, James J.
Whooley, Mary A.
Cohen, Beth E.
Publication Title: 
Journal of Biological Regulators and Homeostatic Agents

There is increasing evidence that psychosocial stress can be viewed as a system-wide derangement of cellular homeostasis, with heightened oxidative stress and triggered proinflammatory mechanisms. The aim of this study is twofold: a) to replicate findings that psychological stress increases oxidative damage and b) to determine whether a fermented papaya preparation known to exert significant protective antioxidant properties could buffer such increases in nuclear DNA damage while also inducing epigenetic protective mechanisms.

Author(s): 
Marotta, F.
Naito, Y.
Padrini, F.
Xuewei, X.
Jain, S.
Soresi, V.
Zhou, L.
Catanzaro, R.
Zhong, K.
Polimeni, A.
Chui, D. H.
Publication Title: 
Journal of Psychosomatic Research

OBJECTIVE: Sleep and optimism are important psycho-biological and personality constructs, respectively. However, very little work has examined the causal relationship between them, and none has examined the potential mechanisms operating in the relationship. This study aimed to understand whether sleep quality was a cause or an effect of optimism, and whether depressive mood could explain the relationship.

Author(s): 
Lau, Esther Yuet Ying
Harry Hui, C.
Cheung, Shu-Fai
Lam, Jasmine

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