Vitamin E

Publication Title: 
Biological & Pharmaceutical Bulletin

Artemisinin exerts the antimalarial activity through activation by heme. The hemolysis in malaria results in the elevated levels of plasma heme which may affect the activity of artemisinin. We hypothesized that the extracellular heme would potentiate the antimalarial activity of artemisinin. Hemin (ferric heme) at the pathologic concentrations enhanced the activity of artemisinin against Plasmodium falciparum in vitro and increased the levels of the lipid peroxidation products in the presence of artemisinin.

Author(s): 
Tangnitipong, Sunanta
Thaptimthong, Thitiporn
Srihirun, Sirada
Unchern, Supeenun
Kittikool, Dusadee
Udomsangpetch, Rachanee
Sibmooh, Nathawut
Publication Title: 
BioFactors (Oxford, England)

Natural leaves and flowers containing numerous aroma chemicals are widely used in aromatherapy since ancient times. In addition to their pleasant smells, aroma chemicals might have some beneficial health effects. Aroma extracts, isolated from coffee beans, soybeans, and mung beans by steam distillation under mild conditions (55 degrees C and 85 mm Hg) were examined for their antioxidative activities. The inhibitory effect of these extracts toward hexanal/hexanoic acid conversion was measured in the testing solution over prolonged time periods.

Author(s): 
Lee, K. G.
Mitchell, A.
Shibamoto, T.
Publication Title: 
Annals of Internal Medicine

BACKGROUND: Women commonly use soy products, herbs, and other complementary and alternative medicine (CAM) therapies for menopausal symptoms. Randomized, controlled trials have evaluated the efficacy and short-term safety of these therapies. PURPOSE: To review randomized, controlled trials of CAM therapies for menopausal symptoms in order to better inform practice and guide future research.

Author(s): 
Kronenberg, Fredi
Fugh-Berman, Adriane
Publication Title: 
Journal of Ethnopharmacology

Ayurveda, practised in India, identified a large number of plant components to be used in the diet for the prevention or the delayed development of degenerative disorders. They include some of the commonly used spices, namely pepper and ginger. The Materia Medica includes both naturally occurring and artificially produced salts, as a partial substitute for common salt. Health promoting herbs and spices which are classified pharmacologically as rejuvenating, nourishing, invigorating, cleansing, wound-healing, etc., are used as food additives.

Author(s): 
Shanmugasundaram, K. R.
Ramanujam, S.
Shanmugasundaram, E. R.
Publication Title: 
Annals of Internal Medicine

BACKGROUND: Women commonly use soy products, herbs, and other complementary and alternative medicine (CAM) therapies for menopausal symptoms. Randomized, controlled trials have evaluated the efficacy and short-term safety of these therapies. PURPOSE: To review randomized, controlled trials of CAM therapies for menopausal symptoms in order to better inform practice and guide future research.

Author(s): 
Kronenberg, Fredi
Fugh-Berman, Adriane
Publication Title: 
Phytotherapy research: PTR

The present study was carried out to investigate the antioxidant effect of an ethanolic extract of Coccinia indica leaves, an indigenous plant used in Ayurvedic Medicine in India, in Streptozotocin-diabetic rats. Oral administration of Coccinia indica leaf extract (CLEt) (200 mg/kg body weight) for 45 days resulted in a significant reduction in plasma thiobarbituric acid reactive substances, hydroperoxides, vitamin E and ceruloplasmin. The extract also caused a significant increase in plasma vitamin C and reduced glutathione, which clearly shows the antioxidant property of CLEt.

Author(s): 
Venkateswaran, S.
Pari, L.
Publication Title: 
Fundamental & Clinical Pharmacology

The effect of Pongamia pinnata (an indigenous plant used in Ayurvedic Medicine in India) leaf extract (PPEt) on circulatory lipid peroxidation and antioxidant status was evaluated in ammonium chloride-induced hyperammonemic rats. Enhanced lipid peroxidation in the circulation of ammonium chloride-treated rats was accompanied by a significant decrease in the levels of vitamin A, vitamin C, vitamin E, reduced glutathione (GSH), glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT).

Author(s): 
Essa, M. Mohamed
Subramanian, P.
Publication Title: 
Clinical Hemorheology and Microcirculation

The purpose of this study was to compare the short-term effects of an intensive lifestyle modification (ILM) program on lipid peroxidation and antioxidant systems in patients with coronary artery disease (CAD). Twenty-two patients in the control group continued to receive their conventional treatment with lipid-lowering drugs, whereas 22 patients in the experimental group were assigned to intensive lifestyle modification (ILM) without taking any lipid-lowering agent.

Author(s): 
Jatuporn, Srisakul
Sangwatanaroj, Somkiat
Saengsiri, Aem-Orn
Rattanapruks, Sopida
Srimahachota, Suphot
Uthayachalerm, Wasan
Kuanoon, Wanpen
Panpakdee, Orasa
Tangkijvanich, Pisit
Tosukhowong, Piyaratana
Publication Title: 
Annals of Internal Medicine

BACKGROUND: Women commonly use soy products, herbs, and other complementary and alternative medicine (CAM) therapies for menopausal symptoms. Randomized, controlled trials have evaluated the efficacy and short-term safety of these therapies. PURPOSE: To review randomized, controlled trials of CAM therapies for menopausal symptoms in order to better inform practice and guide future research.

Author(s): 
Kronenberg, Fredi
Fugh-Berman, Adriane
Publication Title: 
Circulation

BACKGROUND: Although diabetes confers an increased propensity toward accelerated atherogenesis, data are lacking on monocyte activity in type 2 diabetic patients with (DM2-MV) and without (DM2) macrovascular disease compared with control subjects.

Author(s): 
Devaraj, S.
Jialal, I.

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