Age Distribution

Publication Title: 
Journal of the American Geriatrics Society

OBJECTIVES: To assess the cause of death for centenarians' offspring and controls. DESIGN: Cross-sectional study. SETTING: Community-based, nationwide sample. PARTICIPANTS: Family pedigree information was collected on 295 offspring of centenarians (from 106 families with a parent already enrolled in the nationwide New England Centenarian Study) and on 276 controls (from 82 control families) from 1997 to 2000. Controls were individuals whose parents were born in the same year as the centenarians but at least one of whom died at the average life expectancy.

Terry, Dellara F.
Wilcox, Marsha A.
McCormick, Maegan A.
Pennington, JaeMi Y.
Schoenhofen, Emily A.
Andersen, Stacy L.
Perls, Thomas T.
Publication Title: 

As the elderly population is increasing rapidly, there is a lot of scientific interest in clarifying the differential life-style, genetic, biochemical and molecular factors contributing to mortality or exceptional longevity. Within the framework of the ZINCAGE project, 249 old (60-85 years) and nonagenarian Greek subjects (>/=85 years old) were recruited and anthropometrical, blood and biochemical indices as well as blood pressure measurements were obtained.

Kanoni, Stavroula
Dedoussis, George
Manios, Yannis
Malavolta, Marco
Mocchegiani, Eugenio
Publication Title: 

OBJECTIVE: To test whether cholesterol ester transfer protein (CETP) genotype (VV homozygosity for I405V) is associated with preservation of cognitive function in addition to its association with exceptional longevity. METHODS: We studied Ashkenazi Jews with exceptional longevity (n = 158; age 99.2 +/- 0.3 years) for the associations of CETP VV genotype and lipoprotein phenotype, using the Mini-Mental State Examination (MMSE). To confirm the role of CETP in a younger cohort, we studied subjects from the Einstein Aging Study (EAS) for associations between CETP VV and cognitive impairment.

Barzilai, N.
Atzmon, G.
Derby, C. A.
Bauman, J. M.
Lipton, R. B.
Publication Title: 

In the Georgia Centenarian Study (Poon et al., Exceptional Longevity, 2006), centenarian cases and young controls are classified according to three categories (age, ethnic origin, and single nucleotide polymorphisms [SNPs] of candidate longevity genes), where each factor has two possible levels. Here we provide methodologies to determine the minimum sample size needed to detect dependence in 2 x 2 x 2 tables based on Fisher's exact test evaluated exactly or by Markov chain Monte Carlo (MCMC), assuming only the case total L and the control total N are known.

Dai, Jianliang
Li, Li
Kim, Sangkyu
Kimball, Beth
Jazwinski, S. Michal
Arnold, Jonathan
Georgia Centenarian Study
Publication Title: 
Revista EspaÒola De Salud P˙blica

BACKGROUND: Women in the region of Navarra, Spain, have one of the highest life expectancies at birth in Europe. The aim of this study is to assess the completeness of the official mortality statistics of Navarra in 2009 and the impact of the under-registration of deaths on life expectancy estimates.

Moreno-Iribas, Conchi
Guevara, Marcela
DÌaz-Gonz·lez, Jorge
¡lvarez-Arruti, Nerea
Casado, Itziar
Delfrade, Josu
Larumbe, Emilia
Aguirre, Jes˙s
Florist·n, Yugo
Publication Title: 
Human Biology

The purpose of this study was to review published studies on the variability of age at menarche and age at menopause throughout the world, and to identify the main causes for age variation in the timing of these events. We first present a summary table including mean (or median) values of the age at menarche in 67 countries, and of the age at menopause in 26 countries.

Thomas, F.
Renaud, F.
Benefice, E.
de Mee¸s, T.
Guegan, J. F.
Publication Title: 
The Gerontologist

PURPOSE: Prevalence estimates of healthy behaviors and preventive care among older adults have not received sufficient attention, despite important health benefits such as longevity and better quality of life. Moreover, little is known about general population prevalences of older adults' efforts to change behavior, motivations to improve health behaviors, and perceived barriers to change.

Newsom, Jason T.
Kaplan, Mark S.
Huguet, Nathalie
McFarland, Bentson H.
Publication Title: 
The British Journal of Nutrition

Overall dietary patterns have been associated with health and longevity. We used principal component (PC) and cluster analyses to identify the prevailing dietary patterns of 99 744 participants, aged 60 years or older, living in nine European countries and participating in the European Prospective Investigation into Cancer and Nutrition (EPIC-Elderly cohort) and to examine their socio-demographic and lifestyle correlates.

Bamia, Christina
Orfanos, Philippos
Ferrari, Pietro
Overvad, Kim
Hundborg, Heidi H.
Tj¯nneland, Anne
Olsen, Anja
Kesse, Emmanuelle
Boutron-Ruault, Marie-Christine
Clavel-Chapelon, FranÁoise
Nagel, Gabriele
Boffetta, Paolo
Boeing, Heiner
Hoffmann, Kurt
Trichopoulos, Dimitrios
Baibas, Nikos
Psaltopoulou, Theodora
Norat, Teresa
Slimani, Nadia
Palli, Domenico
Krogh, Vittorio
Panico, Salvatore
Tumino, Rosario
Sacerdote, Carlotta
Bueno-de-Mesquita, H. B.
Ocké, Marga C.
Peeters, Petra H.
van Rossum, Caroline T.
QuirÛs, JosÈ-RamÛn
S·nchez, MarÌa-JosÈ
Navarro, Carmen
Barricarte, Aurelio
Dorronsoro, Miren
Berglund, Gˆran
Wirf‰lt, Elisabet
Hallmans, Gˆran
Johansson, Ingegerd
Bingham, Sheila
Khaw, Kay-Tee
Spencer, Elizabeth A.
Roddam, Andrew W.
Riboli, Elio
Trichopoulou, Antonia
Publication Title: 
PloS One

It is often claimed that genes affecting health in old age, such as cardiovascular and Alzheimer diseases, are beyond the reach of natural selection. We show in a simulation study based on known genetic (apolipoprotein E) and non-genetic risk factors (gender, diet, smoking, alcohol, exercise) that, because there is a statistical distribution of ages at which these genes exert their influence on morbidity and mortality, the effects of selection are in fact non-negligible.

Drenos, Fotios
Kirkwood, Thomas B. L.
Publication Title: 
Meat Science

This review starts by introducing the history and underlying culture of meat production and consumption in Japan since early times, and the effects of social change on these parameters. Meat processing in Japan is described, and certain other related papers are also introduced. Automatic machines for meat cutting have been developed by the Japanese food industry and are currently being used throughout the world, particularly in Europe.

Sakata, Ryoichi


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