Immunity

Publication Title: 
Tijdschrift Voor Gerontologie En Geriatrie

Ageing in immune reactivity is described at the level of lymphoid cells, at that of lymphoid organs and organ function, and at that of regulation of cell and organ function. Apart from shifts in numbers of lymphoid cell subpopulations, the decrease in communication capacity between lymphoid cell populations and in binding of invaders (like bacteria) is an important aspect of ageing. These aspects may contribute to the decreased immune reactivity to invaders and the enhanced incidence of immune reactions to self-components (autoimmune reactivity).

Author(s): 
Schuurman, H. J.
Lokhorst, H. M.
Publication Title: 
Best Practice & Research. Clinical Endocrinology & Metabolism

Sex differences in lifespan exist world-wide, with women outliving men by more than a decade in some countries. The gender gap is not a uniquely human phenomenon; most sexually reproducing species examined show sex differences in patterns of ageing, yet a comprehensive explanation does not exist. Here, we discuss how ageing responds to natural selection on traits that arise as a consequence of sexuality.

Author(s): 
Regan, Jennifer C.
Partridge, Linda
Publication Title: 
Best Practice & Research. Clinical Endocrinology & Metabolism

Sex differences in lifespan exist world-wide, with women outliving men by more than a decade in some countries. The gender gap is not a uniquely human phenomenon; most sexually reproducing species examined show sex differences in patterns of ageing, yet a comprehensive explanation does not exist. Here, we discuss how ageing responds to natural selection on traits that arise as a consequence of sexuality.

Author(s): 
Regan, Jennifer C.
Partridge, Linda
Publication Title: 
Federation Proceedings
Author(s): 
Walford, R. L.
Publication Title: 
Geriatrics
Author(s): 
Kent, S.
Publication Title: 
Advances in Experimental Medicine and Biology
Author(s): 
Young, V. R.
Publication Title: 
Terapevticheski? Arkhiv
Author(s): 
Mazharov, M. K.
Publication Title: 
Advances in Experimental Medicine and Biology
Author(s): 
Makinodan, T.
Publication Title: 
Minerva Medica
Author(s): 
Cavalieri, U.
Publication Title: 
Zhonghua Yi Xue Za Zhi
Author(s): 
Zhu, Z. M.

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