Muscle Strength

Publication Title: 
Human Movement Science

This study aimed to continue our characterization of finger strength and multi-finger interactions across the lifespan to include those in their 60s and older. Building on our previous study of children, we examined young and elderly adults during isometric finger flexion and extension tasks. Sixteen young and 16 elderly, gender-matched participants produced maximum force using either a single finger or all four fingers in flexion and extension.

Author(s): 
Oliveira, Marcio A.
Hsu, Jeffrey
Park, Jaebum
Clark, Jane E.
Shim, Jae Kun
Publication Title: 
Aging Cell

In mice, monocytes that exhibit a pro-inflammatory profile enter muscle tissue after muscle injury and are crucial for clearance of necrotic tissue and stimulation of muscle progenitor cell proliferation and differentiation. The aim of this study was to test if pro-inflammatory capacity of classically activated (M1) monocytes relates to muscle mass and strength in humans. This study included 191 male and 195 female subjects (mean age 64.2 years (SD 6.4) and 61.9 ± 6.4, respectively) of the Leiden Longevity Study.

Author(s): 
Beenakker, Karel G. M.
Westendorp, Rudi G. J.
de Craen, Anton J. M.
Slagboom, Pieternella E.
van Heemst, Diana
Maier, Andrea B.
Publication Title: 
Current Opinion in Clinical Nutrition and Metabolic Care

PURPOSE OF REVIEW: The role of calorie restriction in humans is controversial. Recently, new data in monkeys and humans have provided new insights into the potential role of calorie restriction in longevity. RECENT FINDINGS: A study in rhesus monkeys showed a reduction in aging-associated mortality. A number of controlled studies have suggested a variety of beneficial effects during studies of 6-12 months in humans. Major negative effects in humans were loss of muscle mass, muscle strength and loss of bone.

Author(s): 
Morley, John E.
Chahla, Elie
Alkaade, Saad
Publication Title: 
The British Journal of Nutrition

The determination of whether increased dietary protein can positively affect health outcomes is hindered by the absence of prospective, randomized trials directly addressing this issue in which all pertinent variables are controlled. Consequently, we can only address the question deductively by considering the support for the rationale underlying the notion of a beneficial effect of increased dietary protein intake. With regard to health outcomes, we have focused on older individuals.

Author(s): 
Wolfe, Robert R.
Publication Title: 
Journal of Neurophysiology

Brief bouts of sublethal ischemia have been shown to protect exposed tissue (ischemic conditioning) and tissues at remote sites (remote ischemic conditioning) against subsequent ischemic challenges. Given that the mechanisms of this protective phenomenon are multifactorial and epigenetic, we postulated that remote limb ischemic conditioning (RLIC) might enhance mechanisms responsible for neural plasticity, and thereby facilitate learning.

Author(s): 
Cherry-Allen, Kendra M.
Gidday, Jeff M.
Lee, Jin-Moo
Hershey, Tamara
Lang, Catherine E.
Publication Title: 
Proceedings of the National Academy of Sciences of the United States of America

Recent studies have identified impairments in neural induction and in striatal and cortical neurogenesis in Huntington's disease (HD) knock-in mouse models and associated embryonic stem cell lines. However, the potential role of these developmental alterations for HD pathogenesis and progression is currently unknown. To address this issue, we used BACHD:CAG-Cre(ERT2) mice, which carry mutant huntingtin (mHtt) modified to harbor a floxed exon 1 containing the pathogenic polyglutamine expansion (Q97).

Author(s): 
Molero, Aldrin E.
Arteaga-Bracho, Eduardo E.
Chen, Christopher H.
Gulinello, Maria
Winchester, Michael L.
Pichamoorthy, Nandini
Gokhan, Solen
Khodakhah, Kamran
Mehler, Mark F.
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

OBJECTIVES: The purpose of this pilot study was to determine whether there are markers that can be used to study the effects of grounding on delayed-onset muscle soreness (DOMS). DESIGN AND SUBJECTS: Eight (8) healthy subjects were exposed to an eccentric exercise that caused DOMS in gastrocnemius muscles of both legs. Four (4) subjects were grounded with electrode patches and patented conductive sheets connected to the earth. Four (4) control subjects were treated identically, except that the grounding systems were not connected to the earth.

Author(s): 
Brown, Dick
Chevalier, Gaétan
Hill, Michael
Publication Title: 
The International Journal of Clinical and Experimental Hypnosis

This preliminary study investigates the combined effect of intensive hypnotherapy and diaphragmatic exercises in the management of stuttering. Fifty-nine clients with stuttering were trained to practice abdominal weightlifting to strengthen their respiratory muscles and to improve their diaphragmatic movements. The weightlifting exercises involved lifting a dumbbell (2.0-4.0 kg) with the abdomen for 2 hours daily for 8 consecutive days. Hypnotherapy was utilized to alleviate anxiety, to boost self-confidence, and to increase motivation for weightlifting exercise.

Author(s): 
Kaya, Yalcin
Alladin, Assen
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

OBJECTIVES: The aim of this study was to determine if aromatherapy acupressure, compared to acupressure alone, was effective in reducing hemiplegic shoulder pain and improving motor power in stroke patients. DESIGN: This work was a randomized, controlled trial. SUBJECTS: Thirty (30) stroke patients with hemiplegic shoulder pain participated in this study. INTERVENTION: Subjects were randomly assigned to either an aromatherapy acupressure group (N = 15) or an acupressure group ( N = 15), with aromatherapy acupressure using lavender, rosemary, and peppermint given only to the former group.

Author(s): 
Shin, Byung-Cheul
Lee, Myeong Soo
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

BACKGROUND: There has been limited study of yoga training as a complementary exercise strategy to manage the symptom of dyspnea in patients with chronic obstructive pulmonary disease (COPD). PURPOSE: The primary purpose of this pilot study was to evaluate a yoga program for its safety, feasibility, and efficacy for decreasing dyspnea intensity (DI) and dyspnea-related distress (DD) in older adults with COPD.

Author(s): 
Donesky-Cuenco, DorAnne
Nguyen, Huong Q.
Paul, Steven
Carrieri-Kohlman, Virginia

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