Cohort Studies

Publication Title: 
The Spine Journal: Official Journal of the North American Spine Society

BACKGROUND CONTEXT: In 2008, the lack of published evidence prevented the Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders (Neck Pain Task Force [NPTF]) from commenting on the effectiveness of psychological interventions for the management of neck pain. PURPOSE: This study aimed to update findings of the NPTF and evaluate the effectiveness of psychological interventions for the management of neck pain and associated disorders (NAD) or whiplash-associated disorders (WAD). STUDY DESIGN/SETTING: This study used systematic review and best-evidence synthesis.

Author(s): 
Shearer, Heather M.
Carroll, Linda J.
Wong, Jessica J.
Côté, Pierre
Varatharajan, Sharanya
Southerst, Danielle
Sutton, Deborah A.
Randhawa, Kristi A.
Yu, Hainan
Mior, Silvano A.
van der Velde, Gabrielle M.
Nordin, Margareta C.
Stupar, Maja
Taylor-Vaisey, Anne L.
Publication Title: 
Journal of Psychosomatic Research

OBJECTIVE: The objective of the present study is to estimate the economic consequences of somatization disorder and functional somatic syndromes such as fibromyalgia and chronic fatigue syndrome, defined as bodily distress syndrome (BDS), when mindfulness therapy is compared with enhanced treatment as usual. METHODS: A total of 119 BDS patients were randomized to mindfulness therapy or enhanced treatment as usual and compared with 5950 matched controls. Register data were analyzed from 10years before their inclusion to 15-month follow-up.

Author(s): 
Fjorback, Lone Overby
Carstensen, Tina
Arendt, Mikkel
Ornbøl, Eva
Walach, Harald
Rehfeld, Emma
Fink, Per
Publication Title: 
Dermatology (Basel, Switzerland)

BACKGROUND: There is increasing evidence for the extensive use of complementary and alternative medicine (CAM) by patients with psoriasis. Clinical research in the arena of CAM and psoriasis treatment is evolving and includes some randomized controlled trials. OBJECTIVE: To study CAM use among patients with psoriasis attending a dermatology clinic in a major university hospital in northern Israel. Prevalence, reasons for CAM use and its relevance to doctor-patient communication were emphasized.

Author(s): 
Ben-Arye, E.
Ziv, M.
Frenkel, M.
Lavi, I.
Rosenman, D.
Publication Title: 
Pharmacoepidemiology and Drug Safety

PURPOSE: The socioeconomic determinants for drug utilization, especially in children, have not been investigated sufficiently so far. The study's aim was the estimation of prevalences and determinants of conventional, homeopathic and phytotherapeutic drugs and expenditures. METHODS: Population-based data on drug utilization of 3,642 children in two German birth cohorts (GINIplus and LISAplus, 10-year follow-up) were collected using a self-administered questionnaire.

Author(s): 
Italia, Salvatore
Batscheider, Ariane
Heinrich, Joachim
Wenig, Christina
Bauer, Carl Peter
Koletzko, Sibylle
Lehmann, Irina
Herbarth, Olf
von Berg, Andrea
Berdel, Dietrich
Hoffmann, Barbara
Schaaf, Beate
Wolfenstetter, Silke B.
Publication Title: 
Journal of Evidence-Based Complementary & Alternative Medicine

Hering's Law Assessment Tool emerged as a systematic outcome assessment tool following homeopathic intervention. The authors intend to modify it and develop a new tool-Patient Response Assessment Tool after Homeopathic Treatment (PRATHoT)-in chronic cases through Delphi technique for systematic categorization of probable outcomes following individualized homeopathic treatment in chronic cases. The PRATHoT was drafted after literature review and iterative Delphi rounds with multidisciplinary expert panel, setting Fleiss ?

Author(s): 
Saha, Subhranil
Koley, Munmun
Arya, Jogendra Singh
Choubey, Gurudev
Ghosh, Shubhamoy
Ganguly, Subhasish
Gosavi, Tejas
Ghosh, Aloke
Ali, Syed Afsar
Gupta, Neeraj
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

OBJECTIVES: The aim of this study was to implement fasting therapy in an inpatient integrative medicine ward and to evaluate safety, acceptance, and effects on health-related outcomes and lifestyle adherence. DESIGN: This was a prospective observational study with consecutive inpatients over 3 [corrected] years. Inclusion and exclusion criteria for fasting therapy were checked by treating physicians and recommendations given. After receiving full information patients decided whether they would participate in fasting.

Author(s): 
Michalsen, Andreas
Hoffmann, Barbara
Moebus, Susanne
Bäcker, Markus
Langhorst, Jost
Dobos, Gustav J.
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

OBJECTIVE: The purpose of this study was to critically appraise and synthesize evidence on the effectiveness of noninvasive interventions, excluding pharmacological treatments, for musculoskeletal thoracic pain. METHODS: Randomized controlled trials (RCTs), cohort studies, and case-control studies evaluating the effectiveness of noninvasive interventions were eligible. We searched MEDLINE, EMBASE, PsycINFO, and the Cochrane Central Register of Controlled Trials accessed through Ovid Technologies, Inc, and CINAHL Plus with Full Text accessed through EBSCOhost from 1990 to 2015.

Author(s): 
Southerst, Danielle
Marchand, Andrée-Anne
Côté, Pierre
Shearer, Heather M.
Wong, Jessica J.
Varatharajan, Sharanya
Randhawa, Kristi
Sutton, Deborah
Yu, Hainan
Gross, Douglas P.
Jacobs, Craig
Goldgrub, Rachel
Stupar, Maja
Mior, Silvano
Carroll, Linda J.
Taylor-Vaisey, Anne
Publication Title: 
BailliËre's Clinical Rheumatology

It has been recognized that the remarkable decline in infant mortality and the extension in human lifespan involving both developing and developed countries alike, has been influenced by social and economic developments and public health orientated measures (such as clean water and sewerage) rather more than by developments in medical research. However, the identification of important disease risk factors for a number of common conditions such as smoking, solar exposure, dietary fat and alcohol has led to further reductions in disease prevalence and mortality, at least in some countries.

Author(s): 
Muirden, K. D.
Publication Title: 
BMC medical genetics

BACKGROUND: Family studies and heritability estimates provide evidence for a genetic contribution to variation in the human life span. METHODS: We conducted a genome wide association study (Affymetrix 100K SNP GeneChip) for longevity-related traits in a community-based sample. We report on 5 longevity and aging traits in up to 1345 Framingham Study participants from 330 families.

Author(s): 
Lunetta, Kathryn L.
D'Agostino, Ralph B.
Karasik, David
Benjamin, Emelia J.
Guo, Chao-Yu
Govindaraju, Raju
Kiel, Douglas P.
Kelly-Hayes, Margaret
Massaro, Joseph M.
Pencina, Michael J.
Seshadri, Sudha
Murabito, Joanne M.
Publication Title: 
Proceedings of the National Academy of Sciences of the United States of America

Rather than being a passive, haphazard process of wear and tear, lifespan can be modulated actively by components of the insulin/insulin-like growth factor I (IGFI) pathway in laboratory animals. Complete or partial loss-of-function mutations in genes encoding components of the insulin/IGFI pathway result in extension of life span in yeasts, worms, flies, and mice. This remarkable conservation throughout evolution suggests that altered signaling in this pathway may also influence human lifespan.

Author(s): 
Suh, Yousin
Atzmon, Gil
Cho, Mi-Ook
Hwang, David
Liu, Bingrong
Leahy, Daniel J.
Barzilai, Nir
Cohen, Pinchas

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