Publication Title: 
BioMed Research International

Background. Acupuncture might have effectiveness in relieving the symptoms of chronic urticaria. There are currently no systematic reviews of acupuncture for chronic urticaria published in English. Objective. We conducted a systematic review to assess the effectiveness and safety of acupuncture for chronic urticaria. Methods. A systematic review and meta-analysis of randomized, controlled trials were performed. The primary outcome was global symptom improvement. Results. We included 6 studies with 406 participants.

Yao, Qin
Li, Shanshan
Liu, Xiaoxu
Qin, Zongshi
Liu, Zhishun
Publication Title: 
Phytotherapy research: PTR

The effects of topical administration of an alcohol extract of the leaves of an evergreen plant, Terminalia chebula, on the healing of rat dermal wounds, in vivo, was assessed. T. chebula treated wounds healed much faster as indicated by improved rates of contraction and a decreased period of epithelialization. Biochemical studies revealed a significant increase in total protein, DNA and collagen contents in the granulation tissues of treated wounds. The levels of hexosamine and uronic acid in these tissues, also increased upto day 8 post-wounding.

Suguna, Lonchin
Singh, Surjeet
Sivakumar, Pitchumani
Sampath, Padmavathi
Chandrakasan, Gowri
Publication Title: 
International Journal of Molecular Medicine

To evaluate whether an aqueous seed extract of Terminalia chebula Retzius inhibited development of atopy in vivo, we used a 2,4-dinitrofluorobenzene (DNFB)-induced animal model of atopic symptoms to investigate the effects of the extract. We measured CD4+ cell numbers by hematoxylin and eosin (H&E) staining, and determined the expression levels of matrix metalloproteinase (MMP)-9, interleukin (IL)-31, and T-bet genes, in this animal model.

Nam, Dong-Yoon
Lee, Jin-Man
Heo, Jin-Chul
Lee, Sang-Han
Publication Title: 
Pharmaceutical Biology

CONTEXT: The galls of Terminalia chebula Retz. (Combretaceae) frequently appear in many Thai Lanna medicinal plant recipes for promotion of longevity. OBJECTIVE: The objective of this study was to evaluate the skin anti-aging of gel containing niosomes loaded with a semi-purified fraction containing gallic acid from T. chebula galls. METHOD: The semi-purified fraction containing phenolic compounds including gallic acid isolated from T.

Manosroi, Aranya
Jantrawut, Pensak
Akihisa, Toshihiro
Manosroi, Worapaka
Manosroi, Jiradej
Publication Title: 
Forschende Komplementarmedizin (2006)

BACKGROUND: This study aimed to formulate a water-in-oil emulsion (formulation) of Terminalia chebula versus its vehicle (base) as control, and investigate its effects on skin melanin, skin erythema, skin moisture content, and transepidermal water loss (TEWL). MATERIAL AND METHODS: Base containing no active material, and formulation containing 5% concentrated extract of T. chebula, were developed. Different stability parameters were monitored at 8, 25, and 40 °C, as well as 40 °C + 75% relative humidity, for a period of 4 weeks.

Akhtar, Naveed
Khan, Ali B.
Muhammad, Said
Ahmed, Mahmood
Khan, Haji M. Shoaib
Rasool, Fatima
Saeed, Tariq
Publication Title: 
Drug Research

Wound is defined as the loss of breaking cellular and functional continuity of the living tissues. Management of wounds is frequently encountered with different problems. Drug resistance and toxicity hindered the development of synthetic antimicrobial agents with wound healing activity. Many plants with potent pharmacological activities may offer better treatment options viz.

Khan, A. A.
Kumar, V.
Singh, B. K.
Singh, R.
Publication Title: 
Journal of Complementary & Integrative Medicine

BACKGROUND: The aim of this study was to evaluate the efficacy of ethanol extract of Terminalia chebula in the treatment of hot water-induced burn wounds and to compare the results with silver sulfadiazine (SSD) in rats. METHODS: Five groups of ten rats were burned with hot water. Animals were administrated with topical cream at control, normal saline, 5%, 10% T. chebula extracts and standard SSD creams. Several parameters were assessed, including wound area, visual inspection of wound, bacteriology assessment, percentage of wound contraction and histopathological examination.

Nasiri, Ebrahim
Hosseinimehr, Seyed Jalal
Azadbakht, Mohammad
Akbari, Jafar
Enayati-Fard, Reza
Azizi, Sohail
Publication Title: 
Oxidative Medicine and Cellular Longevity

The exposure to ultraviolet radiations (UVR) is the key source of skin sunburn; it may produce harmful entities, reactive oxygen species (ROS), leading to aging. The skin can be treated and protected from the injurious effects of ROS by using various pharmaceutical formulations, such as cream. Cream can be loaded with antioxidants to quench ROS leading to photo-protective effects. Moreover, modern medicines depend on ethnobotanicals for protection or treatment of human diseases. This review article summarizes various in vivo antioxidant studies on herbal creams loaded with phyto-extracts.

Jadoon, Saima
Karim, Sabiha
Bin Asad, Muhammad Hassham Hassan
Akram, Muhammad Rouf
Khan, Abida Kalsoom
Malik, Arif
Chen, Chunye
Murtaza, Ghulam
Publication Title: 
Pharmaceutical Biology

CONTEXT: The fruit of Terminalia chebula Retz. (Combretaceae) has been used for several therapeutic purposes in Thai folk medicines. Currently, the ethanol extracts containing antioxidant compounds have shown the ability to promote collagen synthesis. OBJECTIVE: This purpose of this work was to study the effects of the ethanol extract from T. chebula fruit on the inhibition of cutaneous photodamage. MATERIALS AND METHODS: The viability of human skin fibroblasts after incubation with T.

Yakaew, Swanya
Itsarasook, Khwunjit
Ngoenkam, Jatuporn
Jessadayannamaetha, Arum
Viyoch, Jarupa
Ungsurungsie, Malyn
Publication Title: 
Advances in Experimental Medicine and Biology

It has been shown that human diploid cells from various donor ages can be arrested in an essentially nonmitotic state by reducing the serum concentration of the incubation medium from 10 to 0.5 percent. Cells incubated at this serum level maintained the population distribution that was present when the cells reached confluency. The population, which has 90 percent of the cells in the G1 phase of the division cycle, was not static and exhibited a low level of mitotic activity with prolonged interdivision times.

Dell'Orco, R. T.


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